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Details on Person UniProt:P07821 fhuC
| Class:Id | ReferenceGeneProduct:9930933 |
|---|---|
| _chainChangeLog | chain:1-265 for 9930933 added on Fri Feb 21 2025 |
| _displayName | UniProt:P07821 fhuC |
| _timestamp | 2025-02-21 19:47:58 |
| chain | chain:1-265 |
| checksum | 2511770D6D9EE772 |
| comment | FUNCTION Part of the ABC transporter complex FhuCDB involved in iron(3+)-hydroxamate import. Responsible for energy coupling to the transport system.CATALYTIC ACTIVITY ATP + H2O + Fe(3+)-hydroxamate complex-[hydroxamate-binding protein]Side 1 = ADP + phosphate + Fe(3+)-hydroxamate complexSide 2 + [hydroxamate-binding protein]Side 1.ACTIVITY REGULATION ATPase activity is inhibited by vanadate.BIOPHYSICOCHEMICAL PROPERTIES The complex is composed of two ATP-binding proteins (FhuC), a transmembrane protein (FhuB) and a solute-binding protein (FhuD) (PubMed:34887516). FhuC interacts with FhuB (PubMed:1551849).SUBCELLULAR LOCATION FhuB mediates the association of FhuC with the cytoplasmic membrane.INDUCTION Induced 1.6-fold by hydroxyurea.SIMILARITY Belongs to the ABC transporter superfamily. Iron (Fe3+)-hydroxamate importer (TC 3.A.1.14.7) family. |
| created | [InstanceEdit:9930926] Stephan, Ralf, 2024-12-07 |
| description | recommendedName: fullName evidence="5"Iron(3+)-hydroxamate import ATP-binding protein FhuC ecNumber evidence="2 4"7.2.2.16 alternativeName: fullName evidence="5"Ferric hydroxamate uptake protein C alternativeName: fullName evidence="5"Ferrichrome transport ATP-binding protein FhuC alternativeName: fullName evidence="5"Iron(III)-hydroxamate import ATP-binding protein FhuC |
| geneName | fhuC b0151 JW0147 |
| identifier | P07821 |
| isSequenceChanged | FALSE |
| keyword | 3D-structure ATP-binding Cell inner membrane Cell membrane Ion transport Iron Iron transport Membrane Nucleotide-binding Reference proteome Translocase Transport |
| modified | [InstanceEdit:9939033] Weiser, Joel, 2025-02-21 |
| name | fhuC |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| secondaryIdentifier | FHUC_ECOLI P77548 |
| sequenceLength | 265 |
| species | [Species:159879] Escherichia coli |
| (referenceEntity) | [EntityWithAccessionedSequence:9930928] FhuC [plasma membrane] [Escherichia coli] |
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No pathways have been reviewed or authored by UniProt:P07821 fhuC (9930933)
