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Details on Person FhuBCD imports FeAer to the cytosol

Class:Id	Reaction:9930911
_displayName	FhuBCD imports FeAer to the cytosol
_doRelease	TRUE
_timestamp	2025-05-21 07:41:39
authored	[InstanceEdit:9930753] Stephan, Ralf, 2024-12-06
catalystActivity	[CatalystActivity:9930900] siderophore-iron transmembrane transporter activity of FhuBCD [plasma membrane]
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:9930926] Stephan, Ralf, 2024-12-07
disease	[Disease:3134792] bacterial infectious disease
edited	[InstanceEdit:9948470] Stephan, Ralf, 2025-05-21
input	[SimpleEntity:9930903] FeAer [periplasmic space] [SimpleEntity:113592] ATP [cytosol]
internalReviewed	[InstanceEdit:9937184] Matthews, Lisa, 2025-01-30
isChimeric	FALSE
literatureReference	[LiteratureReference:9930905] X-ray crystallographic structures of the Escherichia coli periplasmic protein FhuD bound to hydroxamate-type siderophores and the antibiotic albomycin [LiteratureReference:9930894] Iron(III) hydroxamate transport across the cytoplasmic membrane of Escherichia coli [LiteratureReference:9930907] Cryo-EM reveals unique structural features of the FhuCDB Escherichia coli ferrichrome importer
modified	[InstanceEdit:9930993] Stephan, Ralf, 2024-12-08 [InstanceEdit:9931098] Stephan, Ralf, 2024-12-10 [InstanceEdit:9933047] Stephan, Ralf, 2024-12-23 [InstanceEdit:9937183] Stephan, Ralf, 2025-01-30 [InstanceEdit:9948469] Stephan, Ralf, 2025-05-21
name	FhuBCD imports FeAer to the cytosol
output	[SimpleEntity:9930910] FeAer [cytosol] [SimpleEntity:29370] ADP [cytosol] [SimpleEntity:29372] Pi [cytosol]
precedingEvent	[Reaction:9930902] IutA imports FeAer to the periplasm [Homo sapiens] [Reaction:9930941] Aerobactin binds Fe3+ [Homo sapiens]
relatedSpecies	[Species:159879] Escherichia coli
releaseDate	2025-06-18
reviewStatus	[ReviewStatus:9821383] three stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9930949] R-HSA-9930911.1
structureModified	[InstanceEdit:9930993] Stephan, Ralf, 2024-12-08
summation	[Summation:9930932] FhuBCD transports Fe3+:hydroxamate siderophores from the E.c...
(hasEvent)	[Pathway:9638482] Metal ion assimilation from the host [Homo sapiens]
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No pathways have been reviewed or authored by FhuBCD imports FeAer to the cytosol (9930911)