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Details on Person CCNA:CDK1 phosphorylates CDC25B

Class:IdReaction:9929935
_displayNameCCNA:CDK1 phosphorylates CDC25B
_doReleaseTRUE
_timestamp2025-02-28 16:52:30
authored[InstanceEdit:9929941] Orlic-Milacic, Marija, 2024-11-30
catalystActivity[CatalystActivity:9929667] cyclin-dependent protein serine/threonine kinase activity of p-S-CCNA:p-T161-CDK1 [nucleoplasm]
compartment[Compartment:7660] nucleoplasm
created[InstanceEdit:9929941] Orlic-Milacic, Marija, 2024-11-30
edited[InstanceEdit:9932253] Orlic-Milacic, Marija, 2024-12-18
input[EntityWithAccessionedSequence:69734] CDC25B [nucleoplasm] [Homo sapiens]
[SimpleEntity:29358] ATP [nucleoplasm]
isChimericFALSE
literatureReference[LiteratureReference:9929665] Cyclin A/Cdk1 modulates Plk1 activity in prometaphase to regulate kinetochore-microtubule attachment stability
[LiteratureReference:9929937] Phosphorylation of human CDC25B phosphatase by CDK1-cyclin A triggers its proteasome-dependent degradation
modified[InstanceEdit:9932263] Orlic-Milacic, Marija, 2024-12-18
[InstanceEdit:9936323] Orlic-Milacic, Marija, 2025-01-22
[InstanceEdit:9939565] Orlic-Milacic, Marija, 2025-02-28
nameCCNA:CDK1 phosphorylates CDC25B
output[EntityWithAccessionedSequence:9929936] p-S-CDC25B [nucleoplasm] [Homo sapiens]
[SimpleEntity:113582] ADP [nucleoplasm]
precedingEvent
releaseDate2025-03-26
reviewed[InstanceEdit:9936318] Alwakeel, Alan, 2025-01-02
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9929945] R-HSA-9929935.1
summation[Summation:9929942] CCNA2:CDK1 complex was reported to phosphorylate CDC25B in l...
(hasEvent)[Pathway:69273] Cyclin A/B1/B2 associated events during G2/M transition [Homo sapiens]
(replacementInstances)[_Deleted:9953045] Deletion of instance: 69756
[_Deleted:9953047] Deletion of instance: 69754
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No pathways have been reviewed or authored by CCNA:CDK1 phosphorylates CDC25B (9929935)