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Details on Person SDS dimers:PXLP convert L-Ser to PYR and NH4+

Class:IdReaction:9929460
_displayNameSDS dimers:PXLP convert L-Ser to PYR and NH4+
_doReleaseTRUE
_timestamp2025-02-27 17:31:12
authored[InstanceEdit:9929451] D'Eustachio, Peter, 2024-11-25
catalystActivity[CatalystActivity:9929461] L-serine ammonia-lyase activity of PXLP-SDS dimers [cytosol]
catalystActivityReference[CatalystActivityReference:9929448] L-serine ammonia-lyase activity of PXLP-SDS dimers [cytosol] Enzymatic and biochemical properties of a novel human serine dehydratase isoform
compartment[Compartment:70101] cytosol
created[InstanceEdit:9929424] D'Eustachio, Peter, 2024-11-26
crossReference[DatabaseIdentifier:9929435] RHEA:19170
edited[InstanceEdit:9929424] D'Eustachio, Peter, 2024-11-26
input[SimpleEntity:200736] L-Ser [cytosol]
isChimericFALSE
literatureReference[LiteratureReference:9929443] Enzymatic and biochemical properties of a novel human serine dehydratase isoform
[LiteratureReference:9014718] A catalytic mechanism that explains a low catalytic activity of serine dehydratase like-1 from human cancer cells: crystal structure and site-directed mutagenesis studies
modified[InstanceEdit:9929473] D'Eustachio, Peter, 2024-11-26
[InstanceEdit:9930119] D'Eustachio, Peter, 2024-12-02
[InstanceEdit:9939472] D'Eustachio, Peter, 2025-02-27
nameSDS dimers:PXLP convert L-Ser to PYR and NH4+
L-serine => NH4(+) + pyruvate
output[SimpleEntity:31633] NH4+ [cytosol]
[SimpleEntity:29398] PYR [cytosol]
precedingEvent
releaseDate2025-03-26
reviewed[InstanceEdit:9939473] Hill, David P, 2025-02-27
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9929463] R-HSA-9929460.1
summation[Summation:9929432] Both SDS (L-serine dehydratase/L-threonine deaminase) and SD...
(hasEvent)[Pathway:977347] Serine metabolism [Homo sapiens]
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No pathways have been reviewed or authored by SDS dimers:PXLP convert L-Ser to PYR and NH4+ (9929460)