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Details on Person UniProt:Q10L71 VLN2
| Class:Id | ReferenceGeneProduct:9928299 |
|---|---|
| _chainChangeLog | chain:1-966 for 9928299 added on Fri Feb 21 2025 |
| _displayName | UniProt:Q10L71 VLN2 |
| _timestamp | 2025-08-15 22:12:55 |
| chain | chain:1-966 |
| checksum | 8EC0D8CA76E0C6B6 |
| comment | FUNCTION Ca(2+)-regulated actin-binding protein (By similarity). Binds actin microfilaments (MFs). Involved in actin filament bundling, severing and capping. Caps the barbed end of actin filaments and is able to sever them in a calcium-dependent manner. May regulate cell expansion in developing organs. Required for the regulation of plant architecture via the modulation of polar auxin transport and root gravitropism (PubMed:26486445).SUBCELLULAR LOCATION Mostly expressed in growing tissues.DISRUPTION PHENOTYPE Malformed organs, including twisted roots and shoots at the seedling stage, mainly caused by asymmetrical expansion of cells on the opposite sides of an organ. Increased dynamic actin cytoskeleton network. Hypersensitive gravitropic response, faster recycling of PIN2, and altered auxin distribution.SIMILARITY Belongs to the villin/gelsolin family. |
| created | [InstanceEdit:9928314] Naithani, Sushma, 2024-11-13 |
| description | recommendedName: fullName evidence="6"Villin-2 |
| geneName | VLN2 LOC_Os03g24220 Os03g0356700 OSNPB_030356700 |
| identifier | Q10L71 |
| isSequenceChanged | FALSE |
| keyword | Actin capping Actin-binding Auxin signaling pathway Calcium Cytoplasm Cytoskeleton Reference proteome Repeat |
| modified | [InstanceEdit:9928371] Naithani, Sushma, 2024-11-13 [InstanceEdit:9939033] Weiser, Joel, 2025-02-21 [InstanceEdit:9963647] Weiser, Joel, 2025-08-15 |
| name | VLN2 |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| secondaryIdentifier | VLN2_ORYSJ |
| sequenceLength | 966 |
| species | [Species:1250427] Oryza sativa subsp. japonica |
| (referenceEntity) | [EntityWithAccessionedSequence:9928328] VLN2 [cytosol] [Oryza sativa] |
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No pathways have been reviewed or authored by UniProt:Q10L71 VLN2 (9928299)
