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Details on Person UniProt:P77348 mppA
| Class:Id | ReferenceGeneProduct:9927606 |
|---|---|
| _chainChangeLog | signal peptide:1-22 for 9927606 added on Fri Feb 21 2025;chain:23-537 for 9927606 added on Fri Feb 21 2025 |
| _displayName | UniProt:P77348 mppA |
| _timestamp | 2025-02-21 18:58:59 |
| chain | signal peptide:1-22 chain:23-537 |
| checksum | C6A17656836DC3AC |
| comment | FUNCTION Part of the ABC transporter complex MppA-OppBCDF involved in the uptake of the cell wall murein tripeptide L-alanyl-gamma-D-glutamyl-meso-diaminopimelate (PubMed:9495761). Is involved in the recycling of cell wall peptides (PubMed:9495761). Binds the cell wall peptide L-Ala-D-Gly-gamma-meso-diaminopimelic acid (PubMed:21705338, PubMed:9495761). Can also transport ordinary alpha-linked tripeptides such as Pro-Phe-Lys, but with much lower efficiency than OppA (PubMed:9495761). Cannot bind typical tripeptides such as Lys-Glu-Lys, Lys-Lys-Lys or Ala-Ala-Ala (PubMed:21705338).SUBUNIT The complex is composed of two ATP-binding proteins (OppD and OppF), two transmembrane proteins (OppB and OppC) and a solute-binding protein (MppA).SUBCELLULAR LOCATION Belongs to the bacterial solute-binding protein 5 family. |
| created | [InstanceEdit:9927596] Stephan, Ralf, 2024-11-08 |
| description | recommendedName: fullName evidence="4"Periplasmic murein peptide-binding protein MppA alternativeName: fullName evidence="3"Murein peptide permease A |
| geneName | mppA ynaH b1329 JW1322 |
| identifier | P77348 |
| isSequenceChanged | FALSE |
| keyword | 3D-structure Direct protein sequencing Peptide transport Periplasm Protein transport Reference proteome Signal Transport |
| modified | [InstanceEdit:9939033] Weiser, Joel, 2025-02-21 |
| name | mppA |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| secondaryIdentifier | MPPA_ECOLI |
| sequenceLength | 537 |
| species | [Species:159879] Escherichia coli |
| (referenceEntity) | [EntityWithAccessionedSequence:9927605] MppA [periplasmic space] [Escherichia coli] |
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No pathways have been reviewed or authored by UniProt:P77348 mppA (9927606)
