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Details on Person HmA imports heme to periplasm

Class:IdReaction:9927481
_displayNameHmA imports heme to periplasm
_timestamp2025-08-25 12:46:45
authored[InstanceEdit:9927223] Stephan, Ralf, 2024-11-05
catalystActivity[CatalystActivity:9927478] heme transmembrane transporter activity of HmA:TonB:ExbB:ExbD [cell outer membrane]
compartment[Compartment:20798] cell outer membrane
[Compartment:1222638] periplasmic space
[Compartment:876] plasma membrane
created[InstanceEdit:9927472] Stephan, Ralf, 2024-11-06
disease[Disease:3134792] bacterial infectious disease
edited[InstanceEdit:9948470] Stephan, Ralf, 2025-05-21
input[SimpleEntity:917877] heme [extracellular region]
[SimpleEntity:8858135] H+ [periplasmic space]
internalReviewed[InstanceEdit:9937184] Matthews, Lisa, 2025-01-30
isChimericFALSE
literatureReference[LiteratureReference:9927480] Structural and functional diversity of transient heme binding to bacterial proteins
[LiteratureReference:9927475] Haem acquisition is facilitated by a novel receptor Hma and required by uropathogenic Escherichia coli for kidney infection
modified[InstanceEdit:9931098] Stephan, Ralf, 2024-12-10
[InstanceEdit:9933047] Stephan, Ralf, 2024-12-23
[InstanceEdit:9937183] Stephan, Ralf, 2025-01-30
[InstanceEdit:9948469] Stephan, Ralf, 2025-05-21
[InstanceEdit:9949829] Matthews, Lisa, 2025-05-26
[InstanceEdit:9964562] Matthews, Lisa, 2025-08-25
nameHmA imports heme to periplasm
output[SimpleEntity:9927227] heme [periplasmic space]
[SimpleEntity:70106] H+ [cytosol]
precedingEvent
relatedSpecies[Species:159879] Escherichia coli
releaseDate2025-06-18
reviewStatus[ReviewStatus:9821383] three stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9949868] R-HSA-9927481.1
summation[Summation:9927228] The Hma receptor imports heme to the periplasm. Hma is a Ton...
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