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Details on Person MITF-M-dependent ITGA2 gene expression

Class:IdBlackBoxEvent:9926533
_displayNameMITF-M-dependent ITGA2 gene expression
_doReleaseTRUE
_timestamp2024-11-08 15:57:24
authored[InstanceEdit:9927254] Vu, Hong Nhung, 2024-11-05
[InstanceEdit:9927252] Steingrímsson, Eiríkur, 2024-11-05
compartment[Compartment:7660] nucleoplasm
[Compartment:876] plasma membrane
created[InstanceEdit:9926531] Rothfels, Karen, 2024-11-01
edited[InstanceEdit:9927257] Rothfels, Karen, 2024-11-05
input[EntityWithAccessionedSequence:9926325] ITGA2 gene [nucleoplasm] [Homo sapiens]
internalReviewed[InstanceEdit:9927489] Orlic-Milacic, Marija, 2024-11-06
literatureReference[LiteratureReference:140043] Structural basis of collagen recognition by integrin alpha2beta1
[LiteratureReference:9926869] Structure of the integrin alpha2beta1-binding collagen peptide
[LiteratureReference:215881] alpha11beta1 integrin is a receptor for interstitial collagens involved in cell migration and collagen reorganization on mesenchymal nonmuscle cells
[LiteratureReference:9926815] Integrin structure, activation, and interactions
[LiteratureReference:9926881] Targeting integrin pathways: mechanisms and advances in therapy
[LiteratureReference:9926252] MITF reprograms the extracellular matrix and focal adhesion in melanoma
[LiteratureReference:9926271] Enhancer-targeted genome editing selectively blocks innate resistance to oncokinase inhibition
[LiteratureReference:9907019] Transcription factor MITF and remodeller BRG1 define chromatin organisation at regulatory elements in melanoma cells
[LiteratureReference:9857178] Mitf regulation of Dia1 controls melanoma proliferation and invasiveness
[LiteratureReference:9857533] Novel MITF targets identified using a two-step DNA microarray strategy
[LiteratureReference:9926258] Melanoma plasticity and phenotypic diversity: therapeutic barriers and opportunities
modified[InstanceEdit:9926900] Rothfels, Karen, 2024-11-04
[InstanceEdit:9927255] Rothfels, Karen, 2024-11-05
[InstanceEdit:9927258] Rothfels, Karen, 2024-11-05
[InstanceEdit:9927491] Rothfels, Karen, 2024-11-06
[InstanceEdit:9927681] Rothfels, Karen, 2024-11-08
nameMITF-M-dependent ITGA2 gene expression
output[EntityWithAccessionedSequence:57562] ITGA2 [plasma membrane] [Homo sapiens]
precedingEvent
regulatedBy[NegativeGeneExpressionRegulation:9926436] Negative gene expression regulation by 'MITF-M dimer:ITGA2 gene [nucleoplasm]'
regulationReference[RegulationReference:9926461] Negative gene expression regulation by 'MITF-M dimer:ITGA2 gene [nucleoplasm]' MITF reprograms the extracellular matrix and focal adhesion in melanoma
releaseDate2024-12-04
reviewed[InstanceEdit:9927254] Vu, Hong Nhung, 2024-11-05
[InstanceEdit:9927252] Steingrímsson, Eiríkur, 2024-11-05
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9926536] R-HSA-9926533.1
summation[Summation:9926811] ITGA2 encodes integrin alpha-2, an integrin receptor that di...
(hasEvent)[Pathway:9926550] Regulation of MITF-M-dependent genes involved in extracellular matrix, focal adhesion and epithelial-to-mesenchymal transition [Homo sapiens]
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No pathways have been reviewed or authored by MITF-M-dependent ITGA2 gene expression (9926533)