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Details on Person MITF-M-dependent ITGA2 gene expression
Class:Id BlackBoxEvent:9926533
_displayName MITF-M-dependent ITGA2 gene expression
_doRelease TRUE
_timestamp 2024-11-08 15:57:24
authored [InstanceEdit:9927254] Vu, Hong Nhung, 2024-11-05 [InstanceEdit:9927252] Steingrímsson, Eiríkur, 2024-11-05
compartment [Compartment:7660] nucleoplasm [Compartment:876] plasma membrane
created [InstanceEdit:9926531] Rothfels, Karen, 2024-11-01
edited [InstanceEdit:9927257] Rothfels, Karen, 2024-11-05
input [EntityWithAccessionedSequence:9926325] ITGA2 gene [nucleoplasm] [Homo sapiens]
internalReviewed [InstanceEdit:9927489] Orlic-Milacic, Marija, 2024-11-06
literatureReference [LiteratureReference:140043] Structural basis of collagen recognition by integrin alpha2beta1 [LiteratureReference:9926869] Structure of the integrin alpha2beta1-binding collagen peptide [LiteratureReference:215881] alpha11beta1 integrin is a receptor for interstitial collagens involved in cell migration and collagen reorganization on mesenchymal nonmuscle cells [LiteratureReference:9926815] Integrin structure, activation, and interactions [LiteratureReference:9926881] Targeting integrin pathways: mechanisms and advances in therapy [LiteratureReference:9926252] MITF reprograms the extracellular matrix and focal adhesion in melanoma [LiteratureReference:9926271] Enhancer-targeted genome editing selectively blocks innate resistance to oncokinase inhibition [LiteratureReference:9907019] Transcription factor MITF and remodeller BRG1 define chromatin organisation at regulatory elements in melanoma cells [LiteratureReference:9857178] Mitf regulation of Dia1 controls melanoma proliferation and invasiveness [LiteratureReference:9857533] Novel MITF targets identified using a two-step DNA microarray strategy [LiteratureReference:9926258] Melanoma plasticity and phenotypic diversity: therapeutic barriers and opportunities
modified [InstanceEdit:9926900] Rothfels, Karen, 2024-11-04 [InstanceEdit:9927255] Rothfels, Karen, 2024-11-05 [InstanceEdit:9927258] Rothfels, Karen, 2024-11-05 [InstanceEdit:9927491] Rothfels, Karen, 2024-11-06 [InstanceEdit:9927681] Rothfels, Karen, 2024-11-08
name MITF-M-dependent ITGA2 gene expression
output [EntityWithAccessionedSequence:57562] ITGA2 [plasma membrane] [Homo sapiens]
precedingEvent
regulatedBy [NegativeGeneExpressionRegulation:9926436] Negative gene expression regulation by 'MITF-M dimer:ITGA2 gene [nucleoplasm]'
regulationReference [RegulationReference:9926461] Negative gene expression regulation by 'MITF-M dimer:ITGA2 gene [nucleoplasm]' MITF reprograms the extracellular matrix and focal adhesion in melanoma
releaseDate 2024-12-04
reviewed [InstanceEdit:9927254] Vu, Hong Nhung, 2024-11-05 [InstanceEdit:9927252] Steingrímsson, Eiríkur, 2024-11-05
reviewStatus [ReviewStatus:9821382] five stars
species [Species:48887] Homo sapiens
stableIdentifier [StableIdentifier:9926536] R-HSA-9926533.1
summation [Summation:9926811] ITGA2 encodes integrin alpha-2, an integrin receptor that di...
(hasEvent) [Pathway:9926550] Regulation of MITF-M-dependent genes involved in extracellular matrix, focal adhesion and epithelial-to-mesenchymal transition [Homo sapiens]
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No pathways have been reviewed or authored by MITF-M-dependent ITGA2 gene expression (9926533)