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Details on Person MITF-M-dependent BRCA1 gene expression

Class:Id	BlackBoxEvent:9926521
_displayName	MITF-M-dependent BRCA1 gene expression
_doRelease	TRUE
_timestamp	2024-11-08 15:57:03
authored	[InstanceEdit:9927254] Vu, Hong Nhung, 2024-11-05 [InstanceEdit:9927252] Steingr�msson, Eir�kur, 2024-11-05
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9926531] Rothfels, Karen, 2024-11-01
edited	[InstanceEdit:9927257] Rothfels, Karen, 2024-11-05
input	[EntityWithAccessionedSequence:6797612] BRCA1 gene [nucleoplasm] [Homo sapiens]
internalReviewed	[InstanceEdit:9927489] Orlic-Milacic, Marija, 2024-11-06
isChimeric	FALSE
literatureReference	[LiteratureReference:9926229] BRCA1 is a new MITF target gene [LiteratureReference:9854815] Essential role of microphthalmia transcription factor for DNA replication, mitosis and genomic stability in melanoma [LiteratureReference:9857252] Microphthalmia-associated transcription factor controls the DNA damage response and a lineage-specific senescence program in melanomas [LiteratureReference:9730403] MITF-the first 25 years
modified	[InstanceEdit:9927255] Rothfels, Karen, 2024-11-05 [InstanceEdit:9927258] Rothfels, Karen, 2024-11-05 [InstanceEdit:9927492] Rothfels, Karen, 2024-11-06 [InstanceEdit:9927681] Rothfels, Karen, 2024-11-08
name	MITF-M-dependent BRCA1 gene expression
output	[EntityWithAccessionedSequence:50949] BRCA1 [nucleoplasm] [Homo sapiens]
precedingEvent	[Reaction:9926487] MITF-M binds the BRCA1 gene [Homo sapiens] [Reaction:9857375] MITF dimerizes [Homo sapiens]
regulatedBy	[PositiveGeneExpressionRegulation:9926449] Positive gene expression regulation by 'MITF-M dimer:BRCA1 gene [nucleoplasm]'
regulationReference	[RegulationReference:9926463] Positive gene expression regulation by 'MITF-M dimer:BRCA1 gene [nucleoplasm]' Essential role of microphthalmia transcription factor for DNA replication, mitosis and genomic stability in melanoma
releaseDate	2024-12-04
reviewed	[InstanceEdit:9927254] Vu, Hong Nhung, 2024-11-05 [InstanceEdit:9927252] Steingr�msson, Eir�kur, 2024-11-05
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9926547] R-HSA-9926521.1
summation	[Summation:9926308] BRCA1 expression is regulated by the binding of MITF-M dimer...
(hasEvent)	[Pathway:9825895] Regulation of MITF-M-dependent genes involved in DNA replication, damage repair and senescence [Homo sapiens]
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No pathways have been reviewed or authored by MITF-M-dependent BRCA1 gene expression (9926521)