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Details on Person MITF-M binds PXDN gene

Class:IdReaction:9926491
_displayNameMITF-M binds PXDN gene
_doReleaseTRUE
_timestamp2024-11-08 15:55:01
authored[InstanceEdit:9927254] Vu, Hong Nhung, 2024-11-05
[InstanceEdit:9927252] Steingrímsson, Eiríkur, 2024-11-05
compartment[Compartment:7660] nucleoplasm
created[InstanceEdit:9926473] Rothfels, Karen, 2024-11-01
edited[InstanceEdit:9927257] Rothfels, Karen, 2024-11-05
input[Complex:9825710] MITF-M dimer [nucleoplasm] [Homo sapiens]
[EntityWithAccessionedSequence:8961315] PXDN gene [nucleoplasm] [Homo sapiens]
internalReviewed[InstanceEdit:9927489] Orlic-Milacic, Marija, 2024-11-06
isChimericFALSE
literatureReference[LiteratureReference:9926252] MITF reprograms the extracellular matrix and focal adhesion in melanoma
[LiteratureReference:9926847] Peroxidasin is secreted and incorporated into the extracellular matrix of myofibroblasts and fibrotic kidney
[LiteratureReference:9926832] Peroxidasin is essential for endothelial cell survival and growth signaling by sulfilimine crosslink-dependent matrix assembly
[LiteratureReference:9857178] Mitf regulation of Dia1 controls melanoma proliferation and invasiveness
[LiteratureReference:9730403] MITF-the first 25 years
[LiteratureReference:9926258] Melanoma plasticity and phenotypic diversity: therapeutic barriers and opportunities
modified[InstanceEdit:9926900] Rothfels, Karen, 2024-11-04
[InstanceEdit:9927255] Rothfels, Karen, 2024-11-05
[InstanceEdit:9927258] Rothfels, Karen, 2024-11-05
[InstanceEdit:9927491] Rothfels, Karen, 2024-11-06
[InstanceEdit:9927680] Rothfels, Karen, 2024-11-08
nameMITF-M binds PXDN gene
output[Complex:9926386] MITF-M dimer:PXDN gene [nucleoplasm] [Homo sapiens]
precedingEvent
previousReviewStatus[ReviewStatus:9821383] three stars
releaseDate2024-12-04
reviewed[InstanceEdit:9927254] Vu, Hong Nhung, 2024-11-05
[InstanceEdit:9927252] Steingrímsson, Eiríkur, 2024-11-05
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9926501] R-HSA-9926491.1
summation[Summation:9926822] MITF-M binds to the PXDN gene to repress its expression in m...
(hasEvent)[Pathway:9926550] Regulation of MITF-M-dependent genes involved in extracellular matrix, focal adhesion and epithelial-to-mesenchymal transition [Homo sapiens]
(precedingEvent)[BlackBoxEvent:9926520] MITF-M-dependent PXDN gene expression [Homo sapiens]
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No pathways have been reviewed or authored by MITF-M binds PXDN gene (9926491)