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Details on Person UniProt:A0A0D9RP06 YWHAB
| Class:Id | ReferenceGeneProduct:9926294 |
|---|---|
| _displayName | UniProt:A0A0D9RP06 YWHAB |
| _timestamp | 2024-11-01 00:30:11 |
| comment | FUNCTION: Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negative regulator of osteogenesis. Blocks the nuclear translocation of the phosphorylated form (by AKT1) of SRPK2 and antagonizes its stimulatory effect on cyclin D1 expression resulting in blockage of neuronal apoptosis elicited by SRPK2. Negative regulator of signaling cascades that mediate activation of MAP kinases via AKAP13. {ECO:0000256|ARBA:ARBA00037038}. |
| created | [InstanceEdit:9926293] Rothfels, Karen, 2024-11-01 |
| geneName | YWHAB |
| identifier | A0A0D9RP06 |
| keyword | Coiled coil Reference proteome |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| secondaryIdentifier | A0A0D9RP06_CHLSB |
| species | [Species:9603609] Chlorocebus sabaeus |
| (referenceEntity) | [EntityWithAccessionedSequence:9926332] YWHAB [cytosol] [Chlorocebus sabaeus] |
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No pathways have been reviewed or authored by UniProt:A0A0D9RP06 YWHAB (9926294)
