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Details on Person mammary stem cell

Class:Id	Cell:9925889
_displayName	mammary stem cell
_timestamp	2025-05-28 14:39:03
cellType	[CellType:9927435] mammary stem cell
created	[InstanceEdit:9925885] Orlic-Milacic, Marija, 2024-10-28
markerReference	[MarkerReference:9944102] ALDH1A1 [cytosol] ALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome [MarkerReference:9944104] ALDH1A3 [cytosol] Telomerase-immortalized human mammary stem/progenitor cells with ability to self-renew and differentiate [MarkerReference:9944147] ALDH1A3 mRNA [cytosol] Hybrid Stem Cell States: Insights Into the Relationship Between Mammary Development and Breast Cancer Using Single-Cell Transcriptomics [MarkerReference:9942614] CD44 [plasma membrane] Characterization of cell lines derived from breast cancers and normal mammary tissues for the study of the intrinsic molecular subtypes [MarkerReference:9942608] CD44 mRNA [cytosol] Characterization of cell lines derived from breast cancers and normal mammary tissues for the study of the intrinsic molecular subtypes [MarkerReference:9944289] Man,Man9GlucNAc2,p-3S-CDH1 [plasma membrane] Molecular characterization of TGFbeta-induced epithelial-mesenchymal transition in normal finite lifespan human mammary epithelial cells [MarkerReference:9944283] CDH1 mRNA [cytosol] Molecular characterization of TGFbeta-induced epithelial-mesenchymal transition in normal finite lifespan human mammary epithelial cells [MarkerReference:9941888] EPCAM [plasma membrane] Characterization of bipotent mammary epithelial progenitor cells in normal adult human breast tissue [MarkerReference:9944290] EPCAM mRNA [cytosol] Evidence for a stem cell hierarchy in the adult human breast [MarkerReference:9941930] ERBB2 [plasma membrane] Characterization of bipotent mammary epithelial progenitor cells in normal adult human breast tissue [MarkerReference:9941927] ERBB2 mRNA [cytosol] Characterization of cell lines derived from breast cancers and normal mammary tissues for the study of the intrinsic molecular subtypes [MarkerReference:9941903] ITGA6(24-1130) [plasma membrane] Characterization of bipotent mammary epithelial progenitor cells in normal adult human breast tissue [MarkerReference:9941921] ITGA6 mRNA [cytosol] Characterization of cell lines derived from breast cancers and normal mammary tissues for the study of the intrinsic molecular subtypes [MarkerReference:9942795] ITGB1 [plasma membrane] Telomerase-immortalized human mammary stem/progenitor cells with ability to self-renew and differentiate [MarkerReference:9942787] ITGB1 mRNA [cytosol] Characterization of cell lines derived from breast cancers and normal mammary tissues for the study of the intrinsic molecular subtypes [MarkerReference:9941900] KRT5 [cytosol] Characterization of cell lines derived from breast cancers and normal mammary tissues for the study of the intrinsic molecular subtypes [MarkerReference:9941911] KRT5 mRNA [cytosol] Characterization of cell lines derived from breast cancers and normal mammary tissues for the study of the intrinsic molecular subtypes [MarkerReference:9941906] KRT17 mRNA [cytosol] Characterization of cell lines derived from breast cancers and normal mammary tissues for the study of the intrinsic molecular subtypes [MarkerReference:9945352] TP63-2 [nucleoplasm] Telomerase-immortalized human mammary stem/progenitor cells with ability to self-renew and differentiate
modified	[InstanceEdit:9926091] Orlic-Milacic, Marija, 2024-10-30 [InstanceEdit:9927456] Orlic-Milacic, Marija, 2024-11-05 [InstanceEdit:9941867] Orlic-Milacic, Marija, 2025-03-11 [InstanceEdit:9941905] Orlic-Milacic, Marija, 2025-03-11 [InstanceEdit:9941908] Orlic-Milacic, Marija, 2025-03-11 [InstanceEdit:9941914] Orlic-Milacic, Marija, 2025-03-11 [InstanceEdit:9941920] Orlic-Milacic, Marija, 2025-03-11 [InstanceEdit:9941926] Orlic-Milacic, Marija, 2025-03-11 [InstanceEdit:9941933] Orlic-Milacic, Marija, 2025-03-11 [InstanceEdit:9942628] Orlic-Milacic, Marija, 2025-03-18 [InstanceEdit:9942634] Orlic-Milacic, Marija, 2025-03-18 [InstanceEdit:9942644] Orlic-Milacic, Marija, 2025-03-18 [InstanceEdit:9942651] Orlic-Milacic, Marija, 2025-03-18 [InstanceEdit:9942658] Orlic-Milacic, Marija, 2025-03-18 [InstanceEdit:9942798] Orlic-Milacic, Marija, 2025-03-19 [InstanceEdit:9942974] Orlic-Milacic, Marija, 2025-03-19 [InstanceEdit:9943286] Orlic-Milacic, Marija, 2025-03-25 [InstanceEdit:9944119] Orlic-Milacic, Marija, 2025-04-03 [InstanceEdit:9944151] Orlic-Milacic, Marija, 2025-04-03 [InstanceEdit:9944301] Orlic-Milacic, Marija, 2025-04-03 [InstanceEdit:9945356] Orlic-Milacic, Marija, 2025-04-14 [InstanceEdit:9953068] Orlic-Milacic, Marija, 2025-05-28
name	mammary stem cell MaSC/BiP bipotent mammary progenitor cell
organ	[Anatomy:9953066] mammary gland
proteinMarker	[EntityWithAccessionedSequence:71688] ALDH1A1 [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:2980896] ALDH1A3 [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:9933842] Man,Man9GlucNAc2,p-3S-CDH1 [plasma membrane] [Homo sapiens] [EntityWithAccessionedSequence:1031688] CD44 [plasma membrane] [Homo sapiens] [EntityWithAccessionedSequence:375068] EPCAM [plasma membrane] [Homo sapiens] [EntityWithAccessionedSequence:372889] ERBB2 [plasma membrane] [Homo sapiens] [EntityWithAccessionedSequence:204439] ITGA6(24-1130) [plasma membrane] [Homo sapiens] [EntityWithAccessionedSequence:57596] ITGB1 [plasma membrane] [Homo sapiens] [EntityWithAccessionedSequence:446074] KRT5 [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:9945353] TP63-2 [nucleoplasm] [Homo sapiens]
RNAMarker	[EntityWithAccessionedSequence:9944140] ALDH1A3 mRNA [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:9942609] CD44 mRNA [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:9793365] CDH1 mRNA [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:9944287] EPCAM mRNA [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:9941929] ERBB2 mRNA [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:9941923] ITGA6 mRNA [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:9942793] ITGB1 mRNA [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:9941909] KRT5 mRNA [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:9936346] KRT17 mRNA [cytosol] [Homo sapiens]
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9925915] R-HSA-9925889.1
tissue	[Anatomy:9953065] parenchyma of mammary gland
(cell)	[MarkerReference:9941888] EPCAM [plasma membrane] Characterization of bipotent mammary epithelial progenitor cells in normal adult human breast tissue [MarkerReference:9941900] KRT5 [cytosol] Characterization of cell lines derived from breast cancers and normal mammary tissues for the study of the intrinsic molecular subtypes [MarkerReference:9941903] ITGA6(24-1130) [plasma membrane] Characterization of bipotent mammary epithelial progenitor cells in normal adult human breast tissue [MarkerReference:9941904] KRT14 [cytosol] Characterization of cell lines derived from breast cancers and normal mammary tissues for the study of the intrinsic molecular subtypes [MarkerReference:9941906] KRT17 mRNA [cytosol] Characterization of cell lines derived from breast cancers and normal mammary tissues for the study of the intrinsic molecular subtypes [MarkerReference:9941911] KRT5 mRNA [cytosol] Characterization of cell lines derived from breast cancers and normal mammary tissues for the study of the intrinsic molecular subtypes [MarkerReference:9941917] KRT14 mRNA [cytosol] Characterization of cell lines derived from breast cancers and normal mammary tissues for the study of the intrinsic molecular subtypes [MarkerReference:9941921] ITGA6 mRNA [cytosol] Characterization of cell lines derived from breast cancers and normal mammary tissues for the study of the intrinsic molecular subtypes [MarkerReference:9941927] ERBB2 mRNA [cytosol] Characterization of cell lines derived from breast cancers and normal mammary tissues for the study of the intrinsic molecular subtypes [MarkerReference:9941930] ERBB2 [plasma membrane] Characterization of bipotent mammary epithelial progenitor cells in normal adult human breast tissue List all 27 refering instances
(input)	[CellDevelopmentStep:9925879] Mammary stem cell produces myoepithelial/basal progenitor [Homo sapiens] [CellDevelopmentStep:9927428] Mammary stem cell produces hormone receptor negative luminal progenitor cell [Homo sapiens] [CellDevelopmentStep:9960175] Mammary stem cell produces hormone receptor positive luminal progenitor cell [Homo sapiens]
(output)	[CellDevelopmentStep:9925817] Embryonic ectoderm cell produces mammary stem cell [Homo sapiens]
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No pathways have been reviewed or authored by mammary stem cell (9925889)