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Details on Person CD274 mRNA binds miR-34 RISC

Class:IdReaction:9924921
_displayNameCD274 mRNA binds miR-34 RISC
_doReleaseTRUE
_timestamp2025-08-26 07:56:34
authored[InstanceEdit:9964122] Hung, Mien-Chie, Yamaguchi, Hirohito, 2025-08-26
[InstanceEdit:9927358] Tiwari, Krishna, 2024-11-05
compartment[Compartment:70101] cytosol
created[InstanceEdit:9925315] Tiwari, Krishna, 2024-10-16
edited[InstanceEdit:9962761] Gillespie, Marc E, 2025-08-08
input[EntityWithAccessionedSequence:9909617] CD274 mRNA [cytosol] [Homo sapiens]
[DefinedSet:1606685] miR-34 RISC [cytosol] [Homo sapiens]
internalReviewed[InstanceEdit:9929194] D'Eustachio, Peter, 2024-10-18
isChimericFALSE
literatureReference[LiteratureReference:9925014] Tumor suppressor miR-34a targets PD-L1 and functions as a potential immunotherapeutic target in acute myeloid leukemia
[LiteratureReference:9924967] MiR-34a suppresses the proliferation and invasion of gastric cancer by modulating PDL1 in the immune microenvironment
modified[InstanceEdit:9925426] Tiwari, Krishna, 2024-10-16
[InstanceEdit:9929193] Tiwari, Krishna, 2024-11-21
[InstanceEdit:9963582] Gillespie, Marc E, 2025-08-14
[InstanceEdit:9964108] Gillespie, Marc E, 2025-08-19
[InstanceEdit:9964110] Gillespie, Marc E, 2025-08-19
[InstanceEdit:9964120] Gillespie, Marc E, 2025-08-19
[InstanceEdit:9964121] Gillespie, Marc E, 2025-08-19
[InstanceEdit:9964125] Gillespie, Marc E, 2025-08-19
[InstanceEdit:9965199] Matthews, Lisa, 2025-08-26
nameCD274 mRNA binds miR-34 RISC
output[Complex:9925250] CD274 mRNA:miR-34 RISC [cytosol] [Homo sapiens]
precedingEvent
releaseDate2025-09-18
reviewed[InstanceEdit:9964122] Hung, Mien-Chie, Yamaguchi, Hirohito, 2025-08-26
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9925359] R-HSA-9924921.1
summation[Summation:9924885] MicroRNA-34a (miR-34a), a central regulator within the T cel...
(hasEvent)[Pathway:9909620] Regulation of PD-L1(CD274) translation [Homo sapiens]
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No pathways have been reviewed or authored by CD274 mRNA binds miR-34 RISC (9924921)