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Details on Person Circularization of (-)-genomic RNA
Class:Id BlackBoxEvent:9923074
_displayName Circularization of (-)-genomic RNA
_doRelease TRUE
_timestamp 2026-03-03 08:54:55
authored [InstanceEdit:9924070] Stephan, Ralf, 2024-10-07
compartment [Compartment:12045] endoplasmic reticulum membrane
created [InstanceEdit:9923072] Stephan, Ralf, 2024-09-29
disease [Disease:3244610] dengue disease
edited [InstanceEdit:9966335] Stephan, Ralf, 2025-09-18
goBiologicalProcess [GO_BiologicalProcess:8935314] viral genome circularization
input [Complex:9979963] DENV -ssRNA with no secondary structures:RC [endoplasmic reticulum membrane] [Dengue virus type 2]
internalReviewed [InstanceEdit:9925762] Orlic-Milacic, Marija, 2024-10-23
isChimeric FALSE
literatureReference [LiteratureReference:9923533] A 5' RNA element promotes dengue virus RNA synthesis on a circular genome [LiteratureReference:9919995] Molecular Insights into the Flavivirus Replication Complex
modified [InstanceEdit:9923534] Stephan, Ralf, 2024-10-01 [InstanceEdit:9924075] Stephan, Ralf, 2024-10-07 [InstanceEdit:9924077] Stephan, Ralf, 2024-10-07 [InstanceEdit:9924657] Stephan, Ralf, 2024-10-16 [InstanceEdit:9925587] Stephan, Ralf, 2024-10-18 [InstanceEdit:9925765] Stephan, Ralf, 2024-10-24 [InstanceEdit:9954417] Stephan, Ralf, 2025-06-07 [InstanceEdit:9963605] Stephan, Ralf, 2025-08-15 [InstanceEdit:9964203] Stephan, Ralf, 2025-08-20 [InstanceEdit:9966334] Stephan, Ralf, 2025-09-18 [InstanceEdit:9966336] Stephan, Ralf, 2025-09-19 [InstanceEdit:9970207] Stephan, Ralf, 2025-10-29 [InstanceEdit:9970441] Stephan, Ralf, 2025-10-30 [InstanceEdit:9970472] Stephan, Ralf, 2025-10-30 [InstanceEdit:9979964] Stephan, Ralf, 2026-01-23 [InstanceEdit:9980057] Stephan, Ralf, 2026-01-24 [InstanceEdit:9984050] Stephan, Ralf, 2026-03-03
name Circularization of (-)-genomic RNA
output [Complex:9980058] DENV circular genomic -ssRNA:RC [endoplasmic reticulum membrane] [Dengue virus type 2]
precedingEvent
previousReviewStatus [ReviewStatus:9821384] two stars
relatedSpecies [Species:3244621] Dengue virus type 2
releaseDate 2025-12-08
reviewed [InstanceEdit:9966332] Mansur, Daniel Santos, 2025-09-18 [InstanceEdit:9970439] Roque Ascenção, Fernando, 2025-10-29 [InstanceEdit:9984049] Roque Ascenção, Fernando, 2026-03-03
reviewStatus [ReviewStatus:9821382] five stars
species [Species:48887] Homo sapiens
stableIdentifier [StableIdentifier:9923081] R-HSA-9923074.2
structureModified [InstanceEdit:9979964] Stephan, Ralf, 2026-01-23 [InstanceEdit:9980057] Stephan, Ralf, 2026-01-24
summation [Summation:9923514] The 3' and 5' ends of DENV genomic -ssRNA interact via compl...
(hasEvent) [Pathway:9918487] Dengue Virus Genome Translation and Replication [Homo sapiens]
(precedingEvent) [BlackBoxEvent:9923068] NS5 synthesizes plus strand genome [Homo sapiens]
(updatedInstance) [_UpdateTracker:9984570] Update Tracker - [BlackBoxEvent:9923074] Circularization of (-)-genomic RNA - v96:[add_removeInput, add_removeOutput]
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