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Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

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Details on Person NS3 localizes to the mitochondrial matrix

Class:IdBlackBoxEvent:9920575
_displayNameNS3 localizes to the mitochondrial matrix
_doReleaseTRUE
_timestamp2025-10-30 11:50:04
authored[InstanceEdit:9920561] Stephan, Ralf, 2024-09-01
compartment[Compartment:70101] cytosol
[Compartment:5460] mitochondrial matrix
created[InstanceEdit:9920565] Stephan, Ralf, 2024-09-01
disease[Disease:3244610] dengue disease
edited[InstanceEdit:9966335] Stephan, Ralf, 2025-09-18
goBiologicalProcess[GO_BiologicalProcess:9910499] import into the mitochondrion
input[EntityWithAccessionedSequence:3244645] K27polyUb-NS3 [endoplasmic reticulum membrane] [Dengue virus type 2]
internalReviewed[InstanceEdit:9925762] Orlic-Milacic, Marija, 2024-10-23
isChimericFALSE
literatureReference[LiteratureReference:9920581] Mitochondrial Import of Dengue Virus NS3 Protease and Cleavage of GrpEL1, a Cochaperone of Mitochondrial Hsp70
[LiteratureReference:9945287] Differential localization of dengue virus protease affects cell homeostasis and triggers to thrombocytopenia
modified[InstanceEdit:9920810] Stephan, Ralf, 2024-09-04
[InstanceEdit:9924657] Stephan, Ralf, 2024-10-16
[InstanceEdit:9925587] Stephan, Ralf, 2024-10-18
[InstanceEdit:9925761] Stephan, Ralf, 2024-10-23
[InstanceEdit:9945392] Stephan, Ralf, 2025-04-15
[InstanceEdit:9954417] Stephan, Ralf, 2025-06-07
[InstanceEdit:9960009] Stephan, Ralf, 2025-07-04
[InstanceEdit:9963605] Stephan, Ralf, 2025-08-15
[InstanceEdit:9964207] Stephan, Ralf, 2025-08-20
[InstanceEdit:9965549] Stephan, Ralf, 2025-08-30
[InstanceEdit:9966334] Stephan, Ralf, 2025-09-18
[InstanceEdit:9966339] Stephan, Ralf, 2025-09-19
[InstanceEdit:9970207] Stephan, Ralf, 2025-10-29
[InstanceEdit:9970441] Stephan, Ralf, 2025-10-30
[InstanceEdit:9970472] Stephan, Ralf, 2025-10-30
nameNS3 localizes to the mitochondrial matrix
output[EntityWithAccessionedSequence:9920573] NS3 [mitochondrial matrix] [Dengue virus type 2]
precedingEvent
previousReviewStatus[ReviewStatus:9821383] three stars
relatedSpecies[Species:3244621] Dengue virus type 2
releaseDate2025-12-08
reviewed[InstanceEdit:9966332] Mansur, Daniel Santos, 2025-09-18
[InstanceEdit:9970439] Roque Ascenção, Fernando, 2025-10-29
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9920583] R-HSA-9920575.1
structureModified[InstanceEdit:9920810] Stephan, Ralf, 2024-09-04
summation[Summation:9920580] DENV serotype 1 (KX618706) NS3 protein contains a mitochondr...
(hasEvent)[Pathway:9918432] Maturation of DENV proteins [Homo sapiens]
(precedingEvent)[Reaction:9921689] NS3 cleaves GrpEL1 [Homo sapiens]
(replacementInstances)[_Deleted:9965554] Deletion of instance: 9954428
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No pathways have been reviewed or authored by NS3 localizes to the mitochondrial matrix (9920575)
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