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Details on Person Secreted NS1 binds to other cell

Class:IdBlackBoxEvent:9920147
_displayNameSecreted NS1 binds to other cell
_doReleaseTRUE
_timestamp2025-10-30 11:56:32
authored[InstanceEdit:9919049] Stephan, Ralf, 2024-08-19
compartment[Compartment:984] extracellular region
[Compartment:876] plasma membrane
created[InstanceEdit:9920038] Stephan, Ralf, 2024-08-29
disease[Disease:3244610] dengue disease
edited[InstanceEdit:9970471] Stephan, Ralf, 2025-10-30
goBiologicalProcess[GO_BiologicalProcess:1221375] protein localization to plasma membrane
input[Complex:9919955] NS1:HDL [extracellular region] [Homo sapiens]
internalReviewed[InstanceEdit:9925762] Orlic-Milacic, Marija, 2024-10-23
[InstanceEdit:9959999] Matthews, Lisa, 2025-07-04
isChimericFALSE
literatureReference[LiteratureReference:9920076] Secreted NS1 of dengue virus attaches to the surface of cells via interactions with heparan sulfate and chondroitin sulfate E
modified[InstanceEdit:9920561] Stephan, Ralf, 2024-09-01
[InstanceEdit:9924077] Stephan, Ralf, 2024-10-07
[InstanceEdit:9924657] Stephan, Ralf, 2024-10-16
[InstanceEdit:9925705] Stephan, Ralf, 2024-10-22
[InstanceEdit:9925766] Stephan, Ralf, 2024-10-24
[InstanceEdit:9945238] Stephan, Ralf, 2025-04-12
[InstanceEdit:9960000] Stephan, Ralf, 2025-07-04
[InstanceEdit:9960005] Stephan, Ralf, 2025-07-04
[InstanceEdit:9960006] Stephan, Ralf, 2025-07-04
[InstanceEdit:9962306] Stephan, Ralf, 2025-08-03
[InstanceEdit:9963605] Stephan, Ralf, 2025-08-15
[InstanceEdit:9964208] Stephan, Ralf, 2025-08-20
[InstanceEdit:9966338] Stephan, Ralf, 2025-09-19
[InstanceEdit:9970472] Stephan, Ralf, 2025-10-30
nameSecreted NS1 binds to other cell
output[Complex:9920090] NS1 hexamer lipoparticle [plasma membrane] [Dengue virus type 2]
[Complex:265523] spherical HDL [extracellular region] [Homo sapiens]
precedingEvent
previousReviewStatus[ReviewStatus:9821383] three stars
regulatedBy[PositiveRegulation:9837623] Positive regulation by 'HSPGs [plasma membrane]'
regulationReference[RegulationReference:9925710] Positive regulation by 'HSPGs [plasma membrane]' Secreted NS1 of dengue virus attaches to the surface of cells via interactions with heparan sulfate and chondroitin sulfate E
relatedSpecies[Species:3244621] Dengue virus type 2
releaseDate2025-12-08
reviewed[InstanceEdit:9970439] Roque Ascenção, Fernando, 2025-10-29
[InstanceEdit:9970204] Mansur, Daniel Santos, 2025-10-29
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9920194] R-HSA-9920147.1
structureModified[InstanceEdit:9925705] Stephan, Ralf, 2024-10-22
[InstanceEdit:9945238] Stephan, Ralf, 2025-04-12
summation[Summation:9920080] Soluble NS1 binds to the surface of uninfected cells, primar...
(hasEvent)[Pathway:9918481] Dengue Virus-Host Interactions [Homo sapiens]
(precedingEvent)[Reaction:9920623] NS1 binds C4BP [Homo sapiens]
[Reaction:9921198] NS1 binds MMP9 and CTNNB1 [Homo sapiens]
[Reaction:9921202] NS1 binds MMP9 and TJP1 [Homo sapiens]
[Reaction:9921458] NS1 binds TLR4 [Homo sapiens]
[Reaction:9921484] NS1 binds KIR3DL1 [Homo sapiens]
[BlackBoxEvent:9921695] NS1 gets endocytosed [Homo sapiens]
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No pathways have been reviewed or authored by Secreted NS1 binds to other cell (9920147)