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Details on Person UniProt:Q92530 PSMF1
| Class:Id | ReferenceGeneProduct:99144 |
|---|---|
| _chainChangeLog | initiator methionine:1 added on Sat February 7 2015;chain:2-271 added on Sat February 7 2015;initiator methionine:1 for 99144 removed on Fri Nov 03 2023;initiator methionine: for 99144 added on Fri Nov 03 2023;initiator methionine: for 99144 removed on Fri Aug 15 2025;initiator methionine:1 for 99144 added on Fri Aug 15 2025 |
| _displayName | UniProt:Q92530 PSMF1 |
| _timestamp | 2025-08-15 21:02:29 |
| chain | initiator methionine:1 chain:2-271 |
| checksum | C669F8210AFAD727 |
| comment | FUNCTION Plays an important role in control of proteasome function. Inhibits the hydrolysis of protein and peptide substrates by the 20S proteasome. Also inhibits the activation of the proteasome by the proteasome regulatory proteins PA700 and PA28.SUBUNIT Monomer and homodimer. Interacts with FBXO7. Interacts with the 20S proteasome.INTERACTION Belongs to the proteasome inhibitor PI31 family. |
| description | recommendedName: Proteasome inhibitor PI31 subunit shortName: hPI31 |
| geneName | PSMF1 |
| identifier | Q92530 |
| isSequenceChanged | FALSE |
| keyword | 3D-structure Acetylation Cytoplasm Endoplasmic reticulum Methylation Phosphoprotein Proteasome Proteomics identification Reference proteome |
| modified | [InstanceEdit:9836292] Weiser, Joel, 2023-05-25 [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 [InstanceEdit:9926675] Weiser, Joel, 2024-11-03 [InstanceEdit:9963647] Weiser, Joel, 2025-08-15 |
| name | PSMF1 |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| referenceGene | [ReferenceDNASequence:9000785] ENSEMBL:ENSG00000125818 PSMF1 [Homo sapiens] |
| secondaryIdentifier | PSMF1_HUMAN A0AVQ9 D3DVW3 Q9H4I1 |
| sequenceLength | 271 |
| species | [Species:48887] Homo sapiens |
| (referenceEntity) | [EntityWithAccessionedSequence:68818] PSMF1 [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:174308] PSMF1 [nucleoplasm] [Homo sapiens] |
| [Change default viewing format] | |
No pathways have been reviewed or authored by UniProt:Q92530 PSMF1 (99144)
