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Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

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Details on Person Diagram of Mycobacterium tuberculosis biological processes

Class:IdPathwayDiagram:991381
_displayNameDiagram of Mycobacterium tuberculosis biological processes
_timestamp2025-08-18 08:39:18
created[InstanceEdit:991382] Jassal, B, 2010-11-04
height1184
modified[InstanceEdit:5545611] Matthews, Lisa, 2014-05-22
[InstanceEdit:8949389] D'Eustachio, Peter, 2016-11-22
[InstanceEdit:8960447] Jassal, Bijay, 2017-02-02
[InstanceEdit:9635554] Pardo, Agustin, 2019-02-05
[InstanceEdit:9635555] Pardo, Agustin, 2019-02-05
[InstanceEdit:9635623] Pardo, Agustin, 2019-02-06
[InstanceEdit:9636648] Pardo, Agustin, 2019-02-13
[InstanceEdit:9637573] Jassal, Bijay, 2019-02-19
[InstanceEdit:9637599] Pardo, Agustin, 2019-02-19
[InstanceEdit:9637670] Pardo, Agustin, 2019-02-19
[InstanceEdit:9644788] Jassal, Bijay, 2019-04-23
[InstanceEdit:9644814] D'Eustachio, Peter, 2019-04-24
[InstanceEdit:9645116] Wu, G, 2019-05-03
[InstanceEdit:9688536] Matthews, Lisa, 2020-05-14
[InstanceEdit:9689734] Jassal, Bijay, 2020-05-21
[InstanceEdit:9699036] Matthews, Lisa, 2020-09-09
[InstanceEdit:9717544] Jassal, Bijay, 2021-03-11
[InstanceEdit:9962930] Stephan, Ralf, 2025-08-12
[InstanceEdit:9963931] Stephan, Ralf, 2025-08-18
representedPathway[Pathway:870392] Mycobacterium tuberculosis biological processes [Mycobacterium tuberculosis]
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id="340" reactomeId="936619" position="1822 665" bounds="1802 654 41 22" textPosition="1803 654"> <Properties> <displayName>CysO</displayName> </Properties> </org.gk.render.RenderableProtein> <org.gk.render.RenderableProtein id="341" reactomeId="936718" position="2042 724" bounds="2001 713 82 22" textPosition="2005 713"> <Properties> <displayName>CysO-COSH</displayName> </Properties> <NodeAttachments> <org.gk.render.RenderableFeature relativeX="0.21951219512195122" relativeY="0.0" label="SH" trackId="0" reactomeId="936680" /> </NodeAttachments> </org.gk.render.RenderableProtein> <org.gk.render.RenderableProtein id="342" reactomeId="936744" position="1940 671" bounds="1920 660 41 22" textPosition="1921 660"> <Properties> <displayName>MoeZ</displayName> </Properties> </org.gk.render.RenderableProtein> <org.gk.render.RenderableChemical id="345" reactomeId="936706" position="2119 758" bounds="2087 743 65 30" textPosition="2096 747"> <Properties> <displayName>O-P-Ser</displayName> 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<org.gk.render.RenderableComplex id="352" reactomeId="936637" position="2190 882" bounds="2153 871 74 22" textPosition="2158 871" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>Mec-Zn++</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableChemical id="354" reactomeId="29356" position="1420 965" bounds="1399 950 43 30" textPosition="1404 954" /> <org.gk.render.RenderableChemical id="355" reactomeId="936600" position="1416 1022" bounds="1388 1007 57 30" textPosition="1393 1011"> <Properties> <displayName>CYSTA</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableChemical id="356" reactomeId="936714" position="1650 1022" bounds="1617 1007 67 30" textPosition="1622 1011"> <Properties> <displayName>2OBUTA</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableChemical id="357" reactomeId="29382" position="1571 1033" bounds="1550 1018 42 30" textPosition="1555 1022"> <Properties> <displayName>NH3</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableComplex id="358" reactomeId="937193" position="1503 937" bounds="1466 914 74 46" textPosition="1468 924" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>PXLP-K208-MetB dimer</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableChemical id="537" reactomeId="870330" position="2622 212" bounds="2605 197 34 30" textPosition="2609 201"> <Properties> <displayName>I1P</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableComplex id="538" reactomeId="879258" position="2489 158" bounds="2452 147 75 22" textPosition="2457 147" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>Ino1-Zn2+</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableChemical id="540" reactomeId="30537" position="2369 213" bounds="2349 198 40 30" textPosition="2354 202" /> <org.gk.render.RenderableChemical id="543" reactomeId="162756" position="2653 284" bounds="2608 269 91 30" textPosition="2617 273"> <Properties> <displayName>UDP-GlcNAc</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableChemical id="544" reactomeId="29356" position="2941 161" bounds="2920 146 43 30" textPosition="2925 150" /> <org.gk.render.RenderableChemical id="545" reactomeId="879263" position="2932 274" bounds="2883 259 98 30" textPosition="2893 263"> <Properties> <displayName>GlcNAc-Ins-P</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableProtein id="546" reactomeId="879291" position="2784 166" bounds="2763 155 42 22" textPosition="2764 155"> <Properties> <displayName>MshA</displayName> </Properties> </org.gk.render.RenderableProtein> <org.gk.render.RenderableChemical id="548" reactomeId="110096" position="2940 215" bounds="2920 200 41 30" textPosition="2925 204"> <Properties> <displayName>UDP</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableChemical id="551" reactomeId="29356" position="3028 222" bounds="3007 207 43 30" textPosition="3012 211" /> <org.gk.render.RenderableChemical id="552" reactomeId="879332" position="3271 271" bounds="3229 256 84 30" textPosition="3237 260"> <Properties> <displayName>GlcNAc-Ins</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableChemical id="553" reactomeId="29372" position="3245 225" bounds="3232 210 27 30" textPosition="3236 214" /> <org.gk.render.RenderableProtein id="554" reactomeId="879317" position="3135 217" bounds="3115 206 40 22" textPosition="3117 206"> <Properties> <displayName>ImpC</displayName> </Properties> </org.gk.render.RenderableProtein> <org.gk.render.RenderableChemical id="557" reactomeId="879264" position="2384 442" bounds="2360 427 48 30" textPosition="2366 431"> <Properties> <displayName>GlcNI</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableChemical id="558" reactomeId="113592" position="2457 369" bounds="2437 354 40 30" textPosition="2441 358" /> <org.gk.render.RenderableChemical id="559" reactomeId="879313" position="2688 443" bounds="2662 428 52 30" textPosition="2666 432"> <Properties> <displayName>DAMT</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableComplex id="560" reactomeId="879241" position="2527 382" bounds="2486 371 82 22" textPosition="2490 371" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>MshC-Zn2+</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableChemical id="562" reactomeId="111707" position="2392 378" bounds="2366 363 52 30" textPosition="2373 367"> <Properties> <displayName>L-Cys</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableChemical id="564" reactomeId="76577" position="2690 398" bounds="2669 383 42 30" textPosition="2673 387"> <Properties> <displayName>AMP</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableChemical id="566" reactomeId="111294" position="2609 490" bounds="2593 475 33 30" textPosition="2597 479" /> <org.gk.render.RenderableChemical id="569" reactomeId="879289" position="3069 442" bounds="3048 427 42 30" textPosition="3052 431" lineColor="255 0 0" isForDisease="true"> <Properties> <displayName>MSH</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableProtein id="570" reactomeId="879286" position="2889 382" bounds="2868 371 42 22" textPosition="2869 371"> <Properties> <displayName>MshD</displayName> </Properties> </org.gk.render.RenderableProtein> <org.gk.render.RenderableChemical id="572" reactomeId="76183" position="2792 393" bounds="2760 378 64 30" textPosition="2768 382" /> <org.gk.render.RenderableChemical id="574" reactomeId="76194" position="2985 402" bounds="2953 387 64 30" textPosition="2960 391"> <Properties> <displayName>CoA-SH</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableChemical id="577" reactomeId="29356" position="3306 347" bounds="3285 332 43 30" textPosition="3290 336" /> <org.gk.render.RenderableComplex id="578" reactomeId="879260" position="3198 475" bounds="3161 464 74 22" textPosition="3165 464" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>mca:Zn2+</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableChemical id="580" reactomeId="29416" position="3270 622" bounds="3231 607 78 30" textPosition="3240 611"> <Properties> <displayName>CH3COO-</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableChemical id="583" reactomeId="29356" position="3016 495" bounds="2995 480 43 30" textPosition="3000 484" /> <org.gk.render.RenderableEntitySet id="586" reactomeId="879233" position="3119 605" bounds="3077 587 85 36" textPosition="3081 587"> <Properties> <displayName>Electrophilic substrate</displayName> </Properties> </org.gk.render.RenderableEntitySet> <org.gk.render.RenderableEntitySet id="587" reactomeId="879246" position="3071 745" bounds="3006 720 130 50" textPosition="3011 720"> <Properties> <displayName>Electrophilic substrate-mycothiol conjugate</displayName> </Properties> </org.gk.render.RenderableEntitySet> <org.gk.render.RenderableChemical id="590" reactomeId="29356" position="2960 675" bounds="2939 660 43 30" textPosition="2944 664" /> <org.gk.render.RenderableEntitySet id="591" reactomeId="879237" position="2520 747" bounds="2466 722 109 50" textPosition="2471 722"> <Properties> <displayName>Electrophilic substance-mercapturic acid</displayName> </Properties> </org.gk.render.RenderableEntitySet> <org.gk.render.RenderableChemical id="595" reactomeId="879250" position="3351 482" bounds="3325 467 52 30" textPosition="3331 471"> <Properties> <displayName>CH2O</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableChemical id="596" reactomeId="879271" position="3543 498" bounds="3518 483 50 30" textPosition="3523 487"> <Properties> <displayName>FMYC</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableChemical id="599" reactomeId="73473" position="3573 441" bounds="3547 426 52 30" textPosition="3553 430"> <Properties> <displayName>NADH</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableChemical id="601" reactomeId="29360" position="3343 407" bounds="3317 392 53 30" textPosition="3323 396" /> <org.gk.render.RenderableChemical id="603" reactomeId="70106" position="3564 399" bounds="3547 384 35 30" textPosition="3552 388" /> <org.gk.render.RenderableChemical id="608" reactomeId="29356" position="3592 549" bounds="3571 534 43 30" textPosition="3576 538" /> <org.gk.render.RenderableChemical id="609" reactomeId="29460" position="3545 723" bounds="3514 708 63 30" textPosition="3520 712"> <Properties> <displayName>HCOOH</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableChemical id="611" reactomeId="70106" position="3481 700" bounds="3464 685 35 30" textPosition="3469 689" /> <org.gk.render.RenderableChemical id="619" reactomeId="879252" position="3069 303" bounds="3044 288 50 30" textPosition="3048 292" lineColor="255 0 0" isForDisease="true"> <Properties> <displayName>MSSM</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableChemical id="620" reactomeId="879326" position="2992 349" bounds="2977 334 30 30" textPosition="2983 338"> <Properties> <displayName>e-</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableChemical id="622" reactomeId="70106" position="3127 349" bounds="3110 334 35 30" textPosition="3115 338" /> <org.gk.render.RenderableProtein id="624" reactomeId="879285" position="3198 379" bounds="3184 368 29 22" textPosition="3185 368"> <Properties> <displayName>Mtr</displayName> </Properties> </org.gk.render.RenderableProtein> <org.gk.render.RenderableChemical id="627" reactomeId="29366" position="3212 421" bounds="3182 406 60 30" textPosition="3188 410" /> <org.gk.render.RenderableChemical id="629" reactomeId="70106" position="3215 324" bounds="3198 309 35 30" textPosition="3203 313" /> <org.gk.render.RenderableChemical id="631" reactomeId="29364" position="3166 296" bounds="3137 281 59 30" textPosition="3143 285"> <Properties> <displayName>NADPH</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableProtein id="632" reactomeId="1222293" position="998 705" bounds="965 694 66 22" textPosition="968 694"> <Properties> <displayName>TrxA(ox.)</displayName> </Properties> <NodeAttachments> <org.gk.render.RenderableFeature relativeX="0.24242424242424243" relativeY="0.0" label="SS" trackId="0" reactomeId="1222593" /> </NodeAttachments> </org.gk.render.RenderableProtein> <org.gk.render.RenderableComplex id="633" reactomeId="1222283" position="3434 383" bounds="3396 372 76 22" textPosition="3398 372" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>MscR:Zn2+</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableChemical id="637" reactomeId="70106" position="1091 620" bounds="1074 605 35 30" textPosition="1079 609" /> <org.gk.render.RenderableChemical id="638" reactomeId="8949384" position="2476 482" bounds="2449 467 54 30" textPosition="2454 471"> <Properties> <displayName>AcCyS</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableChemical id="639" reactomeId="8960276" position="1583 417" bounds="1523 402 120 30" textPosition="1531 406"> <Properties> <displayName>glucanotrehalose</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableChemical id="647" reactomeId="29356" position="1625 478" bounds="1604 463 43 30" textPosition="1609 467" /> <org.gk.render.RenderableChemical id="649" reactomeId="113592" position="2346 974" bounds="2326 959 40 30" textPosition="2330 963" /> <org.gk.render.RenderableChemical id="650" reactomeId="30495" position="2311 916" bounds="2287 901 48 30" textPosition="2293 905"> <Properties> <displayName>LCFA</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableChemical id="651" reactomeId="9635506" position="2613 914" bounds="2558 892 111 44" textPosition="2566 896"> <Properties> <displayName>LCFA adenylate ester</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableEntitySet id="652" reactomeId="9635422" position="2609 837" bounds="2553 824 112 26" textPosition="2560 826"> <Properties> <displayName>FadD26, FadD28</displayName> </Properties> </org.gk.render.RenderableEntitySet> <org.gk.render.RenderableChemical id="654" reactomeId="111294" position="2538 980" bounds="2522 965 33 30" textPosition="2526 969" /> <org.gk.render.RenderableChemical id="656" reactomeId="70106" position="2340 858" bounds="2323 843 35 30" textPosition="2328 847" /> <org.gk.render.RenderableProtein id="658" reactomeId="9635425" position="3140 1049" bounds="3122 1038 36 22" textPosition="3122 1038"> <Properties> <displayName>Pks5</displayName> </Properties> </org.gk.render.RenderableProtein> <org.gk.render.RenderableComplex id="659" reactomeId="9635481" position="2942 914" bounds="2893 896 98 36" textPosition="2896 896" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>Pks5:LCFA adenylate ester</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableChemical id="667" reactomeId="9635466" position="3100 1002" bounds="3059 987 82 30" textPosition="3068 991"> <Properties> <displayName>S-MM-CoA</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableChemical id="668" reactomeId="113528" position="3205 983" bounds="3184 968 43 30" textPosition="3189 972"> <Properties> <displayName>CO2</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableChemical id="669" reactomeId="29356" position="3309 867" bounds="3288 852 43 30" textPosition="3293 856" /> <org.gk.render.RenderableComplex id="670" reactomeId="9635456" position="3398 908" bounds="3340 897 116 22" textPosition="3344 897" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>Pks5:mycocerosyl</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableChemical id="673" reactomeId="70106" position="2952 974" bounds="2935 959 35 30" textPosition="2940 963" /> <org.gk.render.RenderableChemical id="675" reactomeId="29366" position="3235 841" bounds="3205 826 60 30" textPosition="3211 830" /> <org.gk.render.RenderableChemical id="677" reactomeId="29364" position="3007 1002" bounds="2978 987 59 30" textPosition="2984 991" /> <org.gk.render.RenderableChemical id="679" reactomeId="76194" position="3290 954" bounds="3258 939 64 30" textPosition="3265 943" /> <org.gk.render.RenderableChemical id="681" reactomeId="9635427" position="3460 863" bounds="3418 848 85 30" textPosition="3426 852"> <Properties> <displayName>phthiocerol</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableChemical id="682" reactomeId="9635426" position="3691 910" bounds="3672 895 39 30" textPosition="3673 899" /> <org.gk.render.RenderableProtein id="683" reactomeId="9635441" position="3584 833" bounds="3561 822 46 22" textPosition="3562 822"> <Properties> <displayName>PapA5</displayName> </Properties> </org.gk.render.RenderableProtein> <org.gk.render.RenderableChemical id="689" reactomeId="76577" position="2842 851" bounds="2821 836 42 30" textPosition="2825 840" /> <org.gk.render.RenderableChemical id="691" reactomeId="70106" position="2852 973" bounds="2835 958 35 30" textPosition="2840 962"> <Properties> <displayName>H+</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableChemical id="693" reactomeId="9637592" position="3858 911" bounds="3835 896 46 30" textPosition="3840 900"> <Properties> <displayName>PDIM</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableProtein id="694" reactomeId="9637594" position="3775 834" bounds="3749 823 52 22" textPosition="3751 823"> <Properties> <displayName>MmpL7</displayName> </Properties> </org.gk.render.RenderableProtein> <org.gk.render.RenderableCompartment id="697" reactomeId="1222574" position="2001 613" bounds="132 51 3738 1125" textPosition="3735 83" bgColor="250 240 240" lineColor="255 153 102" insets="158 80 3679 1057"> <Properties> <displayName>cell wall</displayName> </Properties> <Components> <Component id="1" /> <Component id="693" /> <Component id="172" /> </Components> </org.gk.render.RenderableCompartment> <org.gk.render.RenderableProtein id="698" reactomeId="936682" position="1809 827" bounds="1754 816 111 22" textPosition="1760 816"> <Properties> <displayName>PXLP-K65-CysK2</displayName> </Properties> <NodeAttachments> <org.gk.render.RenderableFeature relativeX="0.15315315315315314" relativeY="0.0" label="PP" trackId="0" reactomeId="9644809" /> </NodeAttachments> </org.gk.render.RenderableProtein> <org.gk.render.RenderableChemical id="709" reactomeId="70106" position="1541 229" bounds="1524 214 35 30" textPosition="1529 218" /> <org.gk.render.RenderableChemical id="710" reactomeId="9962426" position="833 322" bounds="810 307 47 31" textPosition="813 311"> <Properties> <displayName>3DHQ</displayName> </Properties> </org.gk.render.RenderableChemical> </Nodes> <Edges> <org.gk.render.RenderableReaction id="2" reactomeId="964912" points="454 296, 454 296, 454 296" position="454 296" lineWidth="1.0"> <Inputs> <Input id="3" points="354 261" /> <Input id="4" points="372 374" /> <Input id="5" points="363 313" /> </Inputs> <Outputs> <Output id="6" points="529 271" /> <Output id="7" points="571 327" /> </Outputs> <Catalysts> <Catalyst id="8" points="454 259" /> </Catalysts> <Properties> <displayName>DHAP from Ery4P and PEP</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="9" reactomeId="964914" points="644 260, 684 260, 727 261" position="684 260" lineWidth="1.0"> <Inputs> <Input id="6" points="608 260" /> <Input id="47" points="623 241" /> </Inputs> <Outputs> <Output id="7" points="604 324" /> <Output id="10" points="771 243" /> <Output id="13" points="830 260" /> <Output id="710" points="807 308" /> </Outputs> <Catalysts> <Catalyst id="14" points="683 214" /> </Catalysts> <Properties> <displayName>DHQ from DAHP dephosphorylation</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="15" reactomeId="964851" points="860 322, 939 322, 987 322" position="939 322" lineWidth="1.0"> <Inputs> <Input id="710" /> </Inputs> <Outputs> <Output id="16" points="1103 322" /> <Output id="17" points="1025 297" /> </Outputs> <Catalysts> <Catalyst id="18" points="939 281" /> </Catalysts> <Properties> <displayName>Dehydratation of DHQ yields DHS</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="19" reactomeId="964842" points="1121 422, 1049 422, 993 422" position="1049 422" lineWidth="1.0"> <Inputs> <Input id="16" points="1132 340" /> <Input id="20" points="1170 388" /> <Input id="51" points="1180 422" /> </Inputs> <Outputs> <Output id="21" points="899 422" /> <Output id="22" points="964 443" /> </Outputs> <Catalysts> <Catalyst id="23" points="1049 396" /> </Catalysts> <Properties> <displayName>Shikimate results from hydration of DHS</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="24" reactomeId="964939" points="812 474, 739 474, 666 474" position="739 474" lineWidth="1.0"> <Inputs> <Input id="25" points="846 489" /> <Input id="21" points="856 440" /> </Inputs> <Outputs> <Output id="26" points="632 450" /> <Output id="27" points="567 475" /> </Outputs> <Catalysts> <Catalyst id="28" points="739 447" /> </Catalysts> <Properties> <displayName>Phosphorylation of shikimate</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="29" reactomeId="964886" points="449 523, 449 564, 449 603" position="449 564" lineWidth="1.0"> <Inputs> <Input id="4" points="367 410" /> <Input id="27" points="513 488" /> </Inputs> <Outputs> <Output id="30" points="495 627" /> <Output id="31" points="409 640" /> </Outputs> <Catalysts> <Catalyst id="32" points="425 564" /> </Catalysts> <Properties> <displayName>EPSP from shikimate 3-phosphate</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="33" reactomeId="964884" points="559 644, 610 644, 655 644" position="610 644" lineWidth="1.0"> <Inputs> <Input id="30" /> </Inputs> <Outputs> <Output id="34" points="759 644" /> <Output id="35" points="747 597" /> </Outputs> <Catalysts> <Catalyst id="36" points="610 620" /> </Catalysts> <Properties> <displayName>Dephosphorylation of EPSP yields chorismate</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="56" reactomeId="868622" points="1410 274, 1457 274, 1511 274" position="1457 274" lineWidth="1.0"> <Inputs> <Input id="57" points="1340 242" /> <Input id="58" points="1367 292" /> </Inputs> <Outputs> <Output id="60" points="1591 274" /> <Output id="59" points="1533 292" /> <Output id="709" points="1531 247" /> </Outputs> <Catalysts> <Catalyst id="61" points="1455 240" /> </Catalysts> <Properties> <displayName>Glucose is transferred from UDP-glucose onto glucose-6-phosphate</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="62" reactomeId="868608" points="1694 333, 1731 333, 1773 333" position="1731 333" lineWidth="1.0"> <Inputs> <Input id="63" points="1668 348" /> <Input id="60" points="1644 296" /> </Inputs> <Outputs> <Output id="64" points="1828 310" /> <Output id="65" points="1819 359" /> </Outputs> <Catalysts> <Catalyst id="66" points="1730 259" /> </Catalysts> <Properties> <displayName>Trehalose-6-phosphate is hydrolyzed to trehalose</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="68" reactomeId="868709" points="1875 182, 1874 216, 1874 260" position="1874 216" lineWidth="1.0"> <Inputs> <Input id="69" /> </Inputs> <Outputs> <Output id="64" /> </Outputs> <Catalysts> <Catalyst id="70" points="1851 215" /> </Catalysts> <Properties> <displayName>Maltose is converted to trehalose</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="72" reactomeId="868658" points="1403 417, 1460 416, 1520 416" position="1460 416" lineWidth="1.0"> <Inputs> <Input id="73" /> </Inputs> <Outputs> <Output id="639" /> </Outputs> <Catalysts> <Catalyst id="75" points="1460 373" /> </Catalysts> <Properties> <displayName>1,4-alpha-glucan is converted to glucanotrehalose</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="77" reactomeId="868657" points="1692 443, 1751 443, 1926 443" position="1751 443" lineWidth="1.0"> <Inputs> <Input id="639" points="1646 431" /> <Input id="647" points="1650 466" /> </Inputs> <Outputs> <Output id="64" points="1882 310" /> <Output id="79" points="1981 378" /> </Outputs> <Catalysts> <Catalyst id="80" points="1750 411" /> </Catalysts> <Properties> <displayName>Glucanotrehalose is hydrolyzed to 1,4-alpha-glucan and trehalose</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="172" reactomeId="936667" points="155 732, 155 731, 215 814" position="155 731" lineWidth="1.0"> <Inputs> <Input id="173" points="203 729" /> <Input id="174" points="93 642" /> </Inputs> <Outputs> <Output id="175" /> </Outputs> <Properties> <displayName>sulfate binds to SubI outside the membrane</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="176" reactomeId="936631" points="320 857, 344 911, 414 911" position="344 911" lineWidth="1.0"> <Inputs> <Input id="177" points="338 837" /> <Input id="178" points="303 814" /> <Input id="175" points="277 845" /> </Inputs> <Outputs> <Output id="179" points="530 911" /> <Output id="173" points="243 728, 414 729" /> <Output id="180" points="468 846" /> <Output id="181" points="470 880" /> </Outputs> <Catalysts> <Catalyst id="182" points="274 909" /> </Catalysts> <Properties> <displayName>sulfate uptake in the cytosol</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="183" reactomeId="936729" points="670 909, 712 909, 761 910" position="712 909" lineWidth="1.0"> <Inputs> <Input id="179" points="600 910" /> <Input id="184" points="619 871" /> </Inputs> <Outputs> <Output id="185" points="850 939" /> <Output id="186" points="866 852" /> </Outputs> <Catalysts> <Catalyst id="187" points="711 874" /> </Catalysts> <Properties> <displayName>sulfate is activated to APS</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="189" reactomeId="936583" points="1067 841, 1134 842, 1182 842" position="1134 842" lineWidth="1.0"> <Inputs> <Input id="190" points="1038 895" /> <Input id="191" points="1000 863" /> <Input id="192" points="1003 892" /> <Input id="186" points="911 841" /> </Inputs> <Outputs> <Output id="193" points="1266 818" /> <Output id="194" points="1268 780" /> <Output id="195" points="1221 866" /> <Output id="196" points="1319 842" /> <Output id="198" stoichiometry="2" points="1273 862" /> </Outputs> <Catalysts> <Catalyst id="187" points="710 818, 710 784, 1133 785" /> </Catalysts> <Properties> <displayName>APS is phosphorylated to PAPS</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="201" reactomeId="936659" points="1345 922, 1345 962, 1280 963" position="1345 962" lineWidth="1.0"> <Inputs> <Input id="202" points="1372 901" /> <Input id="196" points="1344 861" /> </Inputs> <Outputs> <Output id="203" points="1204 933" /> <Output id="186" points="899 860, 977 962" /> </Outputs> <Catalysts> <Catalyst id="204" points="1168 1075" /> </Catalysts> <Properties> <displayName>PAPS is dephosphorylated to APS</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="307" reactomeId="936655" points="949 661, 999 661, 1043 673" position="999 661" lineWidth="1.0"> <Inputs> <Input id="308" points="911 643" /> <Input id="186" points="893 824" /> </Inputs> <Outputs> <Output id="632" points="1013 691" /> <Output id="311" points="1077 690" /> <Output id="309" points="1106 662" /> <Output id="637" stoichiometry="2" points="1077 638" /> </Outputs> <Catalysts> <Catalyst id="312" points="999 614" /> </Catalysts> <Properties> <displayName>sulfite results from reduction of APS</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="315" reactomeId="936703" points="1262 658, 1318 659, 1365 659" position="1318 659" lineWidth="1.0"> <Inputs> <Input id="309" points="1170 658" /> <Input id="316" stoichiometry="6" points="1208 616" /> <Input id="314" stoichiometry="6" points="1181 687" /> </Inputs> <Outputs> <Output id="317" stoichiometry="3" points="1400 632" /> <Output id="318" stoichiometry="6" points="1420 659" /> <Output id="319" points="1426 705" /> </Outputs> <Catalysts> <Catalyst id="320" points="1318 623" /> </Catalysts> <Properties> <displayName>sulfite is reduced to sulfide</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="322" reactomeId="936615" points="1556 660, 1604 660, 1646 660" position="1604 660" lineWidth="1.0"> <Inputs> <Input id="323" points="1536 680" /> <Input id="324" points="1531 641" /> </Inputs> <Outputs> <Output id="325" points="1684 634" /> <Output id="326" points="1681 678" /> </Outputs> <Catalysts> <Catalyst id="327" points="1604 607" /> </Catalysts> <Properties> <displayName>acetylation of serine</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="330" reactomeId="936642" points="1525 768, 1525 814, 1525 887" position="1525 814" lineWidth="1.0"> <Inputs> <Input id="326" points="1681 705" /> <Input id="319" points="1472 736" /> </Inputs> <Outputs> <Output id="331" points="1605 957" /> <Output id="332" points="1578 900" /> </Outputs> <Catalysts> <Catalyst id="333" points="1493 814" /> </Catalysts> <Properties> <displayName>deacetylation of O-acetylserine and sulfhydrylation using CysK1</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="336" reactomeId="936745" points="1714 776, 1714 828, 1714 890" position="1714 828" lineWidth="1.0"> <Inputs> <Input id="326" points="1714 711" /> <Input id="319" points="1472 727" /> </Inputs> <Outputs> <Output id="331" points="1638 957" /> <Output id="332" points="1662 901" /> </Outputs> <Catalysts> <Catalyst id="698" points="1751 827" /> </Catalysts> <Properties> <displayName>deacetylation of O-acetylserine and sulfhydrylation using CysK2</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="339" reactomeId="936590" points="1892 724, 1939 724, 1998 724" position="1939 724" lineWidth="1.0"> <Inputs> <Input id="340" points="1835 679" /> <Input id="319" points="1472 723" /> </Inputs> <Outputs> <Output id="341" /> </Outputs> <Catalysts> <Catalyst id="342" points="1939 685" /> </Catalysts> <Properties> <displayName>sulfur transfer to carrier protein</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="344" reactomeId="936665" points="2042 814, 2042 850, 2042 888" position="2042 850" lineWidth="1.0"> <Inputs> <Input id="341" points="2042 738" /> <Input id="345" points="2098 776" /> </Inputs> <Outputs> <Output id="346" points="1952 931" /> <Output id="347" points="2042 927" /> </Outputs> <Catalysts> <Catalyst id="348" points="2011 850" /> </Catalysts> <Properties> <displayName>OPS is added to the carrier sulfide</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="350" reactomeId="936747" points="2147 937, 2191 938, 2191 975" position="2191 938" lineWidth="1.0"> <Inputs> <Input id="351" points="2119 915" /> <Input id="347" points="2094 939" /> </Inputs> <Outputs> <Output id="331" points="1651 975" /> <Output id="340" points="1821 651, 1821 618, 1924 618, 2237 724, 2237 975" /> </Outputs> <Catalysts> <Catalyst id="352" points="2190 896" /> </Catalysts> <Properties> <displayName>cleavage of L-cysteine from carrier protein</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="353" reactomeId="937192" points="1471 988, 1503 988, 1532 988" position="1503 988" lineWidth="1.0"> <Inputs> <Input id="354" points="1445 974" /> <Input id="355" points="1440 1004" /> </Inputs> <Outputs> <Output id="356" points="1614 1012" /> <Output id="331" points="1593 978" /> <Output id="357" points="1558 1015" /> </Outputs> <Catalysts> <Catalyst id="358" points="1503 963" /> </Catalysts> <Properties> <displayName>Cysteine from cystathionine and vice versa</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="536" reactomeId="879331" points="2392 212, 2485 211, 2602 211" position="2485 211" lineWidth="1.0"> <Inputs> <Input id="540" /> </Inputs> <Outputs> <Output id="537" /> </Outputs> <Catalysts> <Catalyst id="538" points="2488 172" /> </Catalysts> <Properties> <displayName>glucose-6-phosphate is converted to inositol-1-phosphate</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="542" reactomeId="879298" points="2728 212, 2783 213, 2837 213" position="2783 213" lineWidth="1.0"> <Inputs> <Input id="537" points="2642 212" /> <Input id="543" points="2668 266" /> </Inputs> <Outputs> <Output id="544" points="2917 171" /> <Output id="545" points="2908 256" /> <Output id="548" points="2917 214" /> </Outputs> <Catalysts> <Catalyst id="546" points="2783 180" /> </Catalysts> <Properties> <displayName>acetylglucosamine is transferred from UDP-GlcNAc onto inositol-1-phosphate</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="550" reactomeId="879274" points="3083 273, 3134 272, 3187 273" position="3134 272" lineWidth="1.0"> <Inputs> <Input id="551" points="3044 240" /> <Input id="545" points="2984 273" /> </Inputs> <Outputs> <Output id="552" points="3226 272" /> <Output id="553" points="3229 236" /> </Outputs> <Catalysts> <Catalyst id="554" points="3134 231" /> </Catalysts> <Properties> <displayName>acetylglucosamine-inositol-phosphate is dephosphorylated</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="556" reactomeId="879319" points="2476 443, 2528 443, 2562 443" position="2528 443" lineWidth="1.0"> <Inputs> <Input id="557" points="2411 442" /> <Input id="558" points="2460 387" /> <Input id="562" points="2411 396" /> </Inputs> <Outputs> <Output id="559" points="2659 443" /> <Output id="564" points="2666 405" /> <Output id="566" points="2594 472" /> </Outputs> <Catalysts> <Catalyst id="560" points="2527 396" /> </Catalysts> <Properties> <displayName>glucosaminyl-inositol and cysteine are ligated to desacetylmycothiol</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="568" reactomeId="879248" points="2825 443, 2889 442, 2949 442" position="2889 442" lineWidth="1.0"> <Inputs> <Input id="559" points="2717 443" /> <Input id="572" points="2801 411" /> </Inputs> <Outputs> <Output id="569" points="3045 442" /> <Output id="574" points="2971 420" /> </Outputs> <Catalysts> <Catalyst id="570" points="2889 396" /> </Catalysts> <Properties> <displayName>desacetylmycothiol is acetylated to mycothiol using acetyl-CoA</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="576" reactomeId="879327" points="3270 428, 3270 477, 3270 564" position="3270 477" lineWidth="1.0"> <Inputs> <Input id="552" points="3270 289" /> <Input id="577" points="3299 365" /> </Inputs> <Outputs> <Output id="557" points="2384 460, 2389 562" /> <Output id="580" points="3270 604" /> </Outputs> <Catalysts> <Catalyst id="578" points="3238 476" /> </Catalysts> <Properties> <displayName>acetylglucosamine-inositol is deacetylated by Mca</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="582" reactomeId="879281" points="2957 494, 2957 549, 2425 548" position="2957 549" lineWidth="1.0"> <Inputs> <Input id="569" points="3045 451" /> <Input id="583" points="2992 494" /> </Inputs> <Outputs> <Output id="557" points="2389 460" /> <Output id="638" points="2464 500" /> </Outputs> <Catalysts> <Catalyst id="578" points="3171 489, 3021 549" /> </Catalysts> <Properties> <displayName>mycothiol is cleaved to acetylcysteine and glucosaminylinositol</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="585" reactomeId="879273" points="3068 659, 3068 659, 3070 714" position="3068 659" lineWidth="1.0" reactionType="Association"> <Inputs> <Input id="569" points="3068 460" /> <Input id="586" points="3102 629" /> </Inputs> <Outputs> <Output id="587" /> </Outputs> <Properties> <displayName>mycothiol conjugates with electrophilic xenobiotic</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="589" reactomeId="879311" points="2840 703, 2764 703, 2663 703" position="2764 703" lineWidth="1.0"> <Inputs> <Input id="590" points="2936 680" /> <Input id="587" points="3000 733" /> </Inputs> <Outputs> <Output id="591" points="2581 730" /> <Output id="557" points="2381 460, 2366 574" /> </Outputs> <Catalysts> <Catalyst id="578" points="3177 489" /> </Catalysts> <Properties> <displayName>mycothiol S-conjugate is cleaved into mercapturic acid and GlcN-Ins</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="594" reactomeId="879245" points="3388 441, 3434 441, 3480 441" position="3434 441" lineWidth="1.0"> <Inputs> <Input id="569" points="3093 441" /> <Input id="595" points="3364 464" /> <Input id="601" points="3362 425" /> </Inputs> <Outputs> <Output id="596" points="3526 480" /> <Output id="599" points="3544 441" /> <Output id="603" points="3544 407" /> </Outputs> <Catalysts> <Catalyst id="633" points="3434 397" /> </Catalysts> <Properties> <displayName>mycothiol binds formaldehyde and is dehydrogenated</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="607" reactomeId="879293" points="3543 595, 3543 649, 3545 649" position="3543 649" lineWidth="1.0"> <Inputs> <Input id="596" points="3543 516" /> <Input id="608" points="3576 567" /> </Inputs> <Outputs> <Output id="569" points="3093 451" /> <Output id="609" points="3545 705" /> <Output id="611" points="3502 686" /> </Outputs> <Properties> <displayName>formylmycothiol hydrolyzes into mycothiol and formate</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="618" reactomeId="879266" points="3068 424, 3068 381, 3068 348" position="3068 381" lineWidth="1.0"> <Inputs> <Input id="569" stoichiometry="2" /> </Inputs> <Outputs> <Output id="619" points="3068 321" /> <Output id="620" stoichiometry="2" points="3010 348" /> <Output id="622" stoichiometry="2" points="3107 348" /> </Outputs> <Properties> <displayName>mycothiol is oxidized to mycothione</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="623" reactomeId="879322" points="3163 338, 3163 377, 3163 413" position="3163 377" lineWidth="1.0"> <Inputs> <Input id="619" points="3097 312" /> <Input id="629" points="3195 328" /> <Input id="631" points="3164 314" /> </Inputs> <Outputs> <Output id="569" stoichiometry="2" points="3093 435" /> <Output id="627" points="3179 416" /> </Outputs> <Catalysts> <Catalyst id="624" points="3181 378" /> </Catalysts> <Properties> <displayName>mycothione is reduced to mycothiol</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="648" reactomeId="9635480" points="2401 916, 2442 915, 2479 913" position="2442 915" lineWidth="1.0"> <Inputs> <Input id="649" stoichiometry="2" points="2360 956" /> <Input id="650" stoichiometry="2" points="2338 916" /> <Input id="656" stoichiometry="2" points="2355 876" /> </Inputs> <Outputs> <Output id="651" stoichiometry="2" points="2555 913" /> <Output id="654" stoichiometry="2" points="2524 962" /> </Outputs> <Catalysts> <Catalyst id="652" points="2547 836, 2442 836" /> </Catalysts> <Properties> <displayName>FadD26, FadD28 transfer adenylyl group to a LCFA</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="666" reactomeId="9635452" points="3066 909, 3131 908, 3173 908" position="3131 908" lineWidth="1.0"> <Inputs> <Input id="673" stoichiometry="3" points="2973 964" /> <Input id="677" stoichiometry="2" points="3016 984" /> <Input id="667" points="3094 984" /> <Input id="659" stoichiometry="2" points="2994 912" /> </Inputs> <Outputs> <Output id="668" points="3198 965" /> <Output id="669" points="3285 873" /> <Output id="670" stoichiometry="2" points="3337 908" /> <Output id="675" stoichiometry="2" points="3221 859" /> <Output id="679" points="3255 941" /> </Outputs> <Catalysts> <Catalyst id="659" points="2975 893, 3063 849" /> </Catalysts> <Properties> <displayName>Pks5 transforms LFCA adenylate ester to mycocerosyl</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="680" reactomeId="9635440" points="3544 909, 3584 909, 3624 909" position="3584 909" lineWidth="1.0"> <Inputs> <Input id="681" points="3487 881" /> <Input id="670" stoichiometry="2" points="3459 908" /> </Inputs> <Outputs> <Output id="658" stoichiometry="2" points="3161 1049, 3477 1049" /> <Output id="682" points="3669 909" /> </Outputs> <Catalysts> <Catalyst id="683" points="3584 847" /> </Catalysts> <Properties> <displayName>PapA5 transforms mycocerosyl to PDIM</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="657" reactomeId="9635428" points="2731 913, 2776 913, 2818 913" position="2776 913" lineWidth="1.0"> <Inputs> <Input id="651" stoichiometry="2" points="2672 913" /> <Input id="658" stoichiometry="2" points="3119 1048, 2778 1046" /> </Inputs> <Outputs> <Output id="659" stoichiometry="2" points="2890 913" /> <Output id="689" stoichiometry="2" points="2836 869" /> <Output id="691" stoichiometry="2" points="2843 955" /> </Outputs> <Catalysts> <Catalyst id="652" points="2671 836, 2777 836" /> </Catalysts> <Properties> <displayName>FadD26, FadD28 transfer LCFA adenylate ester to Pks5</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="692" reactomeId="9637589" points="3714 910, 3777 911, 3832 911" position="3777 911" lineWidth="1.0"> <Inputs> <Input id="682" /> </Inputs> <Outputs> <Output id="693" /> </Outputs> <Catalysts> <Catalyst id="694" points="3775 848" /> </Catalysts> <Properties> <displayName>MmpL7 transports PDIM from the cytosol to the cell wall</displayName> </Properties> </org.gk.render.RenderableReaction> </Edges> <Pathways /> </Process>
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No pathways have been reviewed or authored by Diagram of Mycobacterium tuberculosis biological processes (991381)
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