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Details on Person OqxA is a transport protein of the Resistance-Nodulation-Cel...

Class:IdSummation:9913667
_displayNameOqxA is a transport protein of the Resistance-Nodulation-Cel...
_timestamp2024-07-04 08:27:18
created[InstanceEdit:9913677] Stephan, Ralf, 2024-06-17
modified[InstanceEdit:9915003] Stephan, Ralf, 2024-07-01
[InstanceEdit:9915279] Stephan, Ralf, 2024-07-04
textOqxA is a transport protein of the Resistance-Nodulation-Cell Division (RND) superfamily which localizes to the plasma membrane. Members of the RND superfamily all probably catalyze substrate efflux via an H+ antiport mechanism, utilizing the proton-motive force (reviewed in Nikaido, 2018). The oqxA gene has been found on plasmids of fluoroquinolone-resistant E.coli, and the protein exports a wide variety of antimicrobials (Hansen et al., 2004; Hansen et al., 2007; reviewed in Ruiz et al., 2012; Shariati et al., 2022).
(summation)[Reaction:9913672] OqxA exports fluoroquinolones [Homo sapiens]
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