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Query author contributions in Reactome

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Details on Person UniProt:Q06323 PSME1

Class:IdReferenceGeneProduct:99136
_chainChangeLogchain:1-249 added on Fri February 6 2015
_displayNameUniProt:Q06323 PSME1
_timestamp2024-11-03 20:07:10
chainchain:1-249
checksum5E27727E5A0B0AAB
commentFUNCTION Implicated in immunoproteasome assembly and required for efficient antigen processing. The PA28 activator complex enhances the generation of class I binding peptides by altering the cleavage pattern of the proteasome.SUBUNIT Heterodimer of PSME1 and PSME2, which forms a hexameric ring. PSME1 can form homoheptamers.INTERACTION By IFNG/IFN-gamma.SIMILARITY Belongs to the PA28 family.
descriptionrecommendedName: Proteasome activator complex subunit 1 alternativeName: 11S regulator complex subunit alpha shortName: REG-alpha alternativeName: Activator of multicatalytic protease subunit 1 alternativeName: Interferon gamma up-regulated I-5111 protein shortName: IGUP I-5111 alternativeName: Proteasome activator 28 subunit alpha shortName: PA28a shortName: PA28alpha
geneNamePSME1
IFI5111
identifierQ06323
isSequenceChangedFALSE
keyword3D-structure
Alternative splicing
Direct protein sequencing
Proteasome
Proteomics identification
Reference proteome
modified[InstanceEdit:143527] Schmidt, EE, 2004-11-12 07:45:10
[InstanceEdit:217385] Schmidt, EE, 2008-03-27 06:23:53
[InstanceEdit:354386] Schmidt, EE, 2008-06-18 04:45:12
[InstanceEdit:384350] Kanapin, AA, 2008-11-26 14:00:39
[InstanceEdit:392885] Kanapin, AA, 2009-03-09 12:07:18
[InstanceEdit:400710] Schmidt, EE, 2009-03-25 05:33:35
[InstanceEdit:423310] Kanapin, AA
[InstanceEdit:435478] Kanapin, AA
[InstanceEdit:435871] Kanapin, AA
[InstanceEdit:447347] Kanapin, AA
[InstanceEdit:525883] Kanapin, AA
[InstanceEdit:613449] Kanapin, AA
[InstanceEdit:797602] Kanapin, AA
[InstanceEdit:937368] Yung, CK
[InstanceEdit:1042053] Yung, CK
[InstanceEdit:1220657] Yung, CK
[InstanceEdit:1300696] Yung, CK
[InstanceEdit:1301627] Yung, CK
[InstanceEdit:1551960] Weiser, JD
[InstanceEdit:1995863] Weiser, JD
[InstanceEdit:2132304] Weiser, JD
[InstanceEdit:2265580] Weiser, JD
[InstanceEdit:2587579] Weiser, JD
[InstanceEdit:3132113] Weiser, JD
[InstanceEdit:4341137] Weiser, JD
[InstanceEdit:5433710] Weiser, JD
[InstanceEdit:5618415] Weiser, JD
[InstanceEdit:5634237] Weiser, JD
[InstanceEdit:5673015] Weiser, JD
[InstanceEdit:8987656] Weiser, JD
[InstanceEdit:9037114] Weiser, JD
[InstanceEdit:9637257] Weiser, JD
[InstanceEdit:9676415] Weiser, JD
[InstanceEdit:9715482] Weiser, JD
[InstanceEdit:9852000] Weiser, Joel, 2023-11-03
[InstanceEdit:9926675] Weiser, Joel, 2024-11-03
namePSME1
referenceDatabase[ReferenceDatabase:2] UniProt
referenceGene[ReferenceDNASequence:8962410] ENSEMBL:ENSG00000092010 PSME1 [Homo sapiens]
secondaryIdentifierPSME1_HUMAN
A6NJG9
H0YNE3
Q6IBM2
Q9UEF4
sequenceLength249
species[Species:48887] Homo sapiens
(isoformParent)[ReferenceIsoform:8977573] UniProt:Q06323-1 PSME1 [Homo sapiens]
[ReferenceIsoform:8977574] UniProt:Q06323-2 PSME1 [Homo sapiens]
[ReferenceIsoform:8977575] UniProt:Q06323-3 PSME1 [Homo sapiens]
(referenceEntity)[EntityWithAccessionedSequence:68812] PSME1 [cytosol] [Homo sapiens]
[EntityWithAccessionedSequence:174320] PSME1 [nucleoplasm] [Homo sapiens]
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No pathways have been reviewed or authored by UniProt:Q06323 PSME1 (99136)