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Query author contributions in Reactome

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Details on Person Diagram of Metal ion assimilation from the host

Class:IdPathwayDiagram:9911634
_displayNameDiagram of Metal ion assimilation from the host
_timestamp2025-08-25 12:46:43
created[InstanceEdit:9911640] Stephan, Ralf, 2024-06-03
height943
modified[InstanceEdit:9911686] Stephan, Ralf, 2024-06-04
[InstanceEdit:9911796] Stephan, Ralf, 2024-06-06
[InstanceEdit:9914244] Stephan, Ralf, 2024-06-22
[InstanceEdit:9925969] Stephan, Ralf, 2024-10-29
[InstanceEdit:9927056] Stephan, Ralf, 2024-11-04
[InstanceEdit:9927223] Stephan, Ralf, 2024-11-05
[InstanceEdit:9927472] Stephan, Ralf, 2024-11-06
[InstanceEdit:9927596] Stephan, Ralf, 2024-11-08
[InstanceEdit:9927925] Stephan, Ralf, 2024-11-09
[InstanceEdit:9927940] Stephan, Ralf, 2024-11-09
[InstanceEdit:9927947] Stephan, Ralf, 2024-11-10
[InstanceEdit:9928038] Stephan, Ralf, 2024-11-11
[InstanceEdit:9928210] Stephan, Ralf, 2024-11-12
[InstanceEdit:9930753] Stephan, Ralf, 2024-12-06
[InstanceEdit:9930993] Stephan, Ralf, 2024-12-08
[InstanceEdit:9931008] Stephan, Ralf, 2024-12-08
[InstanceEdit:9931072] Stephan, Ralf, 2024-12-09
[InstanceEdit:9937182] Stephan, Ralf, 2025-01-30
[InstanceEdit:9949696] Matthews, Lisa, 2025-05-26
[InstanceEdit:9961769] Stephan, Ralf, 2025-07-26
[InstanceEdit:9962929] Stephan, Ralf, 2025-08-12
[InstanceEdit:9964562] Matthews, Lisa, 2025-08-25
representedPathway[Pathway:9638482] Metal ion assimilation from the host [Homo sapiens]
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470" bounds="1651 455 27 31" textPosition="1651 459" /> <org.gk.render.RenderableChemical id="837" reactomeId="8858135" position="1757 251" bounds="1744 238 27 27" textPosition="1744 240" /> <org.gk.render.RenderableEntitySet id="838" reactomeId="9931069" position="1720 133" bounds="1680 122 80 23" textPosition="1695 116" /> <org.gk.render.RenderableChemical id="852" reactomeId="113592" position="1589 458" bounds="1569 443 41 31" textPosition="1574 447"> <Properties> <displayName>ATP</displayName> </Properties> </org.gk.render.RenderableChemical> <org.gk.render.RenderableEntitySet id="853" reactomeId="9931015" position="1553 563" bounds="1513 552 80 23" textPosition="1528 546" /> <org.gk.render.RenderableChemical id="854" reactomeId="29370" position="1564 494" bounds="1544 479 40 31" textPosition="1548 483" /> <org.gk.render.RenderableComplex id="855" reactomeId="9931052" position="1687 561" bounds="1658 550 58 23" textPosition="1658 551" bgColor="204 255 255" hideComponents="true"> <Properties> <displayName>FecBCDE</displayName> </Properties> </org.gk.render.RenderableComplex> <org.gk.render.RenderableChemical id="857" reactomeId="29372" position="1595 518" bounds="1584 509 23 19" textPosition="1586 508" /> </Nodes> <Edges> <org.gk.render.RenderableReaction id="3" reactomeId="9911595" points="196 425, 195 425, 195 423" position="195 425" lineWidth="1.0" isForDisease="true" lineColor="255 0 0"> <Inputs> <Input id="4" points="197 469" /> <Input id="8" points="119 375" /> </Inputs> <Outputs> <Output id="9" points="146 460" /> <Output id="5" points="195 370" /> </Outputs> <Catalysts> <Catalyst id="6" points="161 425" /> </Catalysts> <Properties> <displayName>EntS transports enterobactin from cytosol to periplasmic space</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="7" reactomeId="9911600" points="194 337, 191 218, 215 153" position="191 218" lineWidth="1.0" isForDisease="true" lineColor="255 0 0"> <Inputs> <Input id="5" /> </Inputs> <Outputs> <Output id="10" /> </Outputs> <Catalysts> <Catalyst id="11" points="255 278" /> </Catalysts> <Properties> <displayName>Efflux pump complexes transport enterobactin from periplasmic space to extracellular region</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="15" reactomeId="9911601" points="286 110, 339 109, 380 110" position="339 109" lineWidth="1.0" isForDisease="true" lineColor="255 0 0"> <Inputs> <Input id="16" points="253 95" /> <Input id="10" points="262 116" /> </Inputs> <Outputs> <Output id="17" stoichiometry="5" points="430 88" /> <Output id="18" points="416 128" /> </Outputs> <Properties> <displayName>Enterobactin binds Fe3+</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="19" reactomeId="9911602" points="476 219, 475 218, 475 220" position="475 218" lineWidth="1.0" isForDisease="true" lineColor="255 0 0"> <Inputs> <Input id="18" points="448 159" /> <Input id="783" points="524 234" /> </Inputs> <Outputs> <Output id="20" points="476 259" /> <Output id="785" points="558 431, 541 315" /> </Outputs> <Catalysts> <Catalyst id="781" points="565 290" /> </Catalysts> <Properties> <displayName>FepA:TonB:ExbB:ExbD transports ferrienterobactin from the extracellular region to the periplasmic space</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="22" reactomeId="9911597" points="480 317, 480 317, 480 342" position="480 317" lineWidth="1.0" isForDisease="true" lineColor="255 0 0" reactionType="Association"> <Inputs> <Input id="23" points="435 308" /> <Input id="20" points="478 299" /> </Inputs> <Outputs> <Output id="24" /> </Outputs> <Properties> <displayName>Ferrienterobactin binds to FepB</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="28" reactomeId="9911603" points="479 422, 479 423, 480 423" position="479 423" lineWidth="1.0" isForDisease="true" lineColor="255 0 0"> <Inputs> <Input id="39" points="417 450" /> <Input id="24" points="479 383" /> </Inputs> <Outputs> <Output id="29" points="480 465" /> <Output id="32" points="513 438" /> <Output id="40" points="518 475" /> <Output id="23" points="418 322" /> </Outputs> <Catalysts> <Catalyst id="786" points="437 424" /> </Catalysts> <Properties> <displayName>FepC:FepD:FepG transports ferrienterobactin from the periplasmic space to the cytosol</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="41" reactomeId="9911599" points="481 577, 482 595, 482 620" position="482 595" lineWidth="1.0" isForDisease="true" lineColor="255 0 0"> <Inputs> <Input id="29" points="480 505" /> <Input id="42" stoichiometry="3" points="447 553" /> <Input id="46" points="520 555" /> </Inputs> <Outputs> <Output id="43" points="460 655" /> <Output id="44" stoichiometry="2" points="534 667" /> </Outputs> <Catalysts> <Catalyst id="45" points="526 595" /> </Catalysts> <Properties> <displayName>Fes hydrolyses ferrienterobactin to DHBS</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="47" reactomeId="9911594" points="588 111, 612 112, 635 112" position="612 112" lineWidth="1.0" isForDisease="true" lineColor="255 0 0"> <Inputs> <Input id="48" points="552 128" /> <Input id="50" points="553 95" /> </Inputs> <Outputs> <Output id="49" points="667 126" /> <Output id="55" points="667 93" /> </Outputs> <Properties> <displayName>Ybt binds Fe3+</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="56" reactomeId="9911605" points="828 219, 828 220, 827 220" position="828 220" lineWidth="1.0" isForDisease="true" lineColor="255 0 0"> <Inputs> <Input id="726" points="826 204" /> <Input id="60" points="774 236" /> </Inputs> <Outputs> <Output id="733" points="833 290" /> <Output id="62" points="731 451" /> </Outputs> <Catalysts> <Catalyst id="72" points="739 291" /> </Catalysts> <Properties> <displayName>FyuA transports Ybt:Fe/Cu from extracellular space to the periplasm</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="76" reactomeId="9911596" points="1687 810, 1683 810, 1683 809" position="1687 810" lineWidth="1.0" isForDisease="true" lineColor="255 0 0"> <Inputs> <Input id="87" points="1608 811" /> <Input id="77" points="1720 803" /> </Inputs> <Outputs> <Output id="78" points="1581 775" /> <Output id="88" points="1560 842" /> <Output id="741" points="1598 859" /> </Outputs> <Catalysts> <Catalyst id="79" points="1685 836" /> </Catalysts> <Activators> <Activator id="86" points="1641 862" /> </Activators> <Properties> <displayName>FeoAB transports Fe2+ from periplasmic space to the cytosol</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="90" reactomeId="9911598" points="1720 794, 1687 784, 1581 772" position="1687 784" lineWidth="1.0" isForDisease="true" lineColor="255 0 0"> <Inputs> <Input id="77" /> </Inputs> <Outputs> <Output id="78" /> </Outputs> <Catalysts> <Catalyst id="98" points="1687 751" /> </Catalysts> <Properties> <displayName>EfeUOB transport Fe2+ from periplasmic space to the cytosol</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="99" reactomeId="9926936" points="1281 116, 1315 116, 1359 114" position="1315 116" lineWidth="1.0" isForDisease="true" lineColor="255 0 0" reactionType="Uncertain Process"> <Inputs> <Input id="100" points="1254 100" /> <Input id="101" points="1210 124" /> </Inputs> <Outputs> <Output id="116" stoichiometry="4" points="1491 135" /> <Output id="104" points="1479 52" /> <Output id="103" points="1458 96" /> </Outputs> <Catalysts> <Catalyst id="105" points="1250 43" /> </Catalysts> <Properties> <displayName>EspC(54-1018) cleaves hemoglobin</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="110" reactomeId="9927009" points="1272 137, 1314 141, 1350 141" position="1314 141" lineWidth="1.0" isForDisease="true" lineColor="255 0 0" reactionType="Uncertain Process"> <Inputs> <Input id="101" points="1210 129" /> <Input id="112" points="1204 167" /> <Input id="100" points="1243 109" /> </Inputs> <Outputs> <Output id="116" stoichiometry="2" points="1491 139" /> <Output id="104" points="1486 52" /> <Output id="113" points="1378 153" /> <Output id="103" points="1458 104" /> </Outputs> <Catalysts> <Catalyst id="112" points="1224 180, 1314 178" /> </Catalysts> <Properties> <displayName>Hbp(53-1100) cleaves hemoglobin</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="129" reactomeId="9927224" points="1519 214, 1519 214, 1521 215" position="1519 214" lineWidth="1.0" isForDisease="true" lineColor="255 0 0"> <Inputs> <Input id="116" points="1517 158" /> <Input id="135" points="1431 273" /> </Inputs> <Outputs> <Output id="130" points="1465 307" /> <Output id="133" points="1535 441" /> </Outputs> <Catalysts> <Catalyst id="131" points="1285 306" /> </Catalysts> <Properties> <displayName>ChuA imports heme to periplasm</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="184" reactomeId="9927609" points="1346 357, 1347 358, 1368 373" position="1347 358" lineWidth="1.0" isForDisease="true" lineColor="255 0 0" reactionType="Association"> <Inputs> <Input id="185" points="1335 353" /> <Input id="130" points="1435 329" /> </Inputs> <Outputs> <Output id="186" /> </Outputs> <Properties> <displayName>PBP binds heme</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="204" reactomeId="9927930" points="1388 422, 1388 425, 1389 425" position="1388 425" lineWidth="1.0" isForDisease="true" lineColor="255 0 0"> <Inputs> <Input id="186" points="1388 412" /> <Input id="205" points="1309 477" /> </Inputs> <Outputs> <Output id="185" points="1324 353, 1329 403" /> <Output id="206" points="1374 498" /> <Output id="207" points="1464 462" /> <Output id="210" points="1435 486" /> </Outputs> <Catalysts> <Catalyst id="208" points="1432 424" /> </Catalysts> <Properties> <displayName>DppBCDF transports heme to cytosol</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="245" reactomeId="9927945" points="334 530, 303 542, 264 548" position="303 542" lineWidth="1.0" isForDisease="true" lineColor="255 0 0" reactionType="Uncertain Process"> <Inputs> <Input id="29" stoichiometry="2" points="457 491" /> <Input id="246" points="316 506" /> </Inputs> <Outputs> <Output id="4" stoichiometry="2" points="216 508" /> <Output id="247" points="170 581" /> <Output id="251" stoichiometry="2" points="239 621" /> <Output id="256" points="154 536" /> </Outputs> <Catalysts> <Catalyst id="248" points="342 564" /> </Catalysts> <Inhibitors> <Inhibitor id="249" points="309 605" /> </Inhibitors> <Properties> <displayName>YqjH reduces FeEnt</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="257" reactomeId="9928035" points="1685 646, 1685 646, 1685 648" position="1685 646" lineWidth="1.0" isForDisease="true" lineColor="255 0 0"> <Inputs> <Input id="258" points="1631 658" /> <Input id="259" points="1712 626" /> </Inputs> <Outputs> <Output id="261" points="1654 626" /> <Output id="265" points="1663 681" /> <Output id="267" points="1623 688" /> </Outputs> <Catalysts> <Catalyst id="263" points="1685 606" /> </Catalysts> <Properties> <displayName>ZnuABC transports Zn2+ to cytosol</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="721" reactomeId="9928204" points="875 78, 856 78, 831 78" position="856 78" lineWidth="1.0" isForDisease="true" lineColor="255 0 0"> <Inputs> <Input id="722" points="899 66" /> <Input id="725" points="899 91" /> </Inputs> <Outputs> <Output id="723" points="817 90" /> <Output id="55" points="704 84" /> </Outputs> <Properties> <displayName>Ybt binds Cu2+</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.EntitySetAndMemberLink id="727" points="807 137, 821 169" position="814 153" lineWidth="0.5" lineColor="0 0 0"> <Inputs> <Input id="723" /> </Inputs> <Outputs> <Output id="726" /> </Outputs> </org.gk.render.EntitySetAndMemberLink> <org.gk.render.EntitySetAndMemberLink id="728" points="726 145, 797 169" position="761 157" lineWidth="0.5" lineColor="0 0 0"> <Inputs> <Input id="49" /> </Inputs> <Outputs> <Output id="726" /> </Outputs> </org.gk.render.EntitySetAndMemberLink> <org.gk.render.RenderableReaction id="735" reactomeId="9928256" points="786 426, 788 424, 787 425" position="788 424" lineWidth="1.0" isForDisease="true" lineColor="255 0 0"> <Inputs> <Input id="736" points="761 486" /> <Input id="733" points="829 325" /> </Inputs> <Outputs> <Output id="737" points="825 477" /> <Output id="738" points="792 527" /> <Output id="89" points="870 451" /> </Outputs> <Catalysts> <Catalyst id="739" points="843 424" /> </Catalysts> <Properties> <displayName>YbtPQ transports Ybt:Fe/Cu to the cytosol</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="745" reactomeId="9930941" points="1036 136, 1034 136, 1036 134" position="1034 136" lineWidth="1.0" isForDisease="true" lineColor="255 0 0"> <Inputs> <Input id="746" points="1061 118" /> <Input id="749" points="1016 118" /> </Inputs> <Outputs> <Output id="747" points="1068 153" /> <Output id="751" stoichiometry="3" points="991 165" /> </Outputs> <Properties> <displayName>Aerobactin binds Fe3+</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="752" reactomeId="9930902" points="1093 216, 1095 217, 1095 220" position="1095 217" lineWidth="1.0" isForDisease="true" lineColor="255 0 0"> <Inputs> <Input id="747" points="1092 190" /> <Input id="756" points="1130 233" /> </Inputs> <Outputs> <Output id="753" points="1095 290" /> <Output id="758" points="1019 435" /> </Outputs> <Catalysts> <Catalyst id="754" points="998 292" /> </Catalysts> <Properties> <displayName>IutA imports FeAer to the periplasm</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="762" reactomeId="9930911" points="1096 423, 1096 423, 1095 425" position="1096 423" lineWidth="1.0" isForDisease="true" lineColor="255 0 0"> <Inputs> <Input id="765" points="1043 479" /> <Input id="753" points="1096 327" /> </Inputs> <Outputs> <Output id="767" points="1136 460" /> <Output id="763" points="1097 503" /> <Output id="769" points="1160 450" /> </Outputs> <Catalysts> <Catalyst id="764" points="1131 423" /> </Catalysts> <Properties> <displayName>FhuBCD imports FeAer to the cytosol</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="831" reactomeId="9931043" points="1721 218, 1717 220, 1716 220" position="1717 220" lineWidth="1.0" isForDisease="true" lineColor="255 0 0"> <Inputs> <Input id="838" points="1720 151" /> <Input id="837" points="1741 238" /> </Inputs> <Outputs> <Output id="832" points="1732 387" /> <Output id="835" points="1669 452, 1685 407" /> </Outputs> <Catalysts> <Catalyst id="833" points="1658 291" /> </Catalysts> <Properties> <displayName>FecA:TonB:ExbB:ExbD imports Fe3+-citrates to periplasm</displayName> </Properties> </org.gk.render.RenderableReaction> <org.gk.render.RenderableReaction id="851" reactomeId="9931048" points="1691 507, 1687 509, 1687 509" position="1687 509" lineWidth="1.0" isForDisease="true" lineColor="255 0 0"> <Inputs> <Input id="852" points="1613 467" /> <Input id="832" points="1729 422" /> </Inputs> <Outputs> <Output id="853" points="1581 546" /> <Output id="854" points="1587 496" /> <Output id="857" points="1610 516" /> </Outputs> <Catalysts> <Catalyst id="855" points="1687 547" /> </Catalysts> <Properties> <displayName>FecBCDE imports Fe3+-citrates to cytosol</displayName> </Properties> </org.gk.render.RenderableReaction> </Edges> <Pathways /> </Process>
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