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Details on Person FepA:TonB:ExbB:ExbD transports ferrienterobactin from the extracellular region to the periplasmic space

Class:Id	Reaction:9911602
_displayName	FepA:TonB:ExbB:ExbD transports ferrienterobactin from the extracellular region to the periplasmic space
_doRelease	TRUE
_timestamp	2025-05-21 07:41:04
authored	[InstanceEdit:9638337] Stephan, Ralf, 2019-02-21
catalystActivity	[CatalystActivity:9638408] ferric-enterobactin transmembrane transporter activity of FepA:TonB:ExbB:ExbD [cell outer membrane]
compartment	[Compartment:984] extracellular region [Compartment:1222638] periplasmic space [Compartment:20798] cell outer membrane
created	[InstanceEdit:9911604] Stephan, Ralf, 2024-06-03
disease	[Disease:3134792] bacterial infectious disease
edited	[InstanceEdit:9948470] Stephan, Ralf, 2025-05-21
input	[SimpleEntity:9638324] FeEnt [extracellular region] [SimpleEntity:8858135] H+ [periplasmic space]
internalReviewed	[InstanceEdit:9915005] Gillespie, Marc E, 2024-07-02 [InstanceEdit:9917579] Gillespie, Marc E, 2024-08-08 [InstanceEdit:9937184] Matthews, Lisa, 2025-01-30
isChimeric	FALSE
literatureReference	[LiteratureReference:9638323] Evidence of ball-and-chain transport of ferric enterobactin through FepA
modified	[InstanceEdit:9911640] Stephan, Ralf, 2024-06-03 [InstanceEdit:9915006] Stephan, Ralf, 2024-07-02 [InstanceEdit:9915160] Stephan, Ralf, 2024-07-03 [InstanceEdit:9917580] Stephan, Ralf, 2024-08-08 [InstanceEdit:9931008] Stephan, Ralf, 2024-12-08 [InstanceEdit:9931098] Stephan, Ralf, 2024-12-10 [InstanceEdit:9933047] Stephan, Ralf, 2024-12-23 [InstanceEdit:9937183] Stephan, Ralf, 2025-01-30 [InstanceEdit:9948469] Stephan, Ralf, 2025-05-21
name	FepA:TonB:ExbB:ExbD transports ferrienterobactin from the extracellular region to the periplasmic space
output	[SimpleEntity:9638419] FeEnt [periplasmic space] [SimpleEntity:70106] H+ [cytosol]
precedingEvent	[Reaction:9911601] Enterobactin binds Fe3+ [Homo sapiens] [Reaction:9911600] Efflux pump complexes transport enterobactin from periplasmic space to extracellular region [Homo sapiens]
previousReviewStatus	[ReviewStatus:9821380] one star
relatedSpecies	[Species:159879] Escherichia coli
releaseDate	2025-06-18
reviewStatus	[ReviewStatus:9821383] three stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9911608] R-HSA-9911602.1
structureModified	[InstanceEdit:9931008] Stephan, Ralf, 2024-12-08
summation	[Summation:9638315] Ferrienterobactin receptor (FepA) imports ferrienterobactin ...
(hasEvent)	[Pathway:9638334] Iron assimilation using enterobactin [Homo sapiens]
(precedingEvent)	[Reaction:9911597] Ferrienterobactin binds to FepB [Homo sapiens]
(replacementInstances)	[_Deleted:9911633] Deletion of instance: 9638362
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No pathways have been reviewed or authored by FepA:TonB:ExbB:ExbD transports ferrienterobactin from the extracellular region to the periplasmic space (9911602)