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Details on Person Fes hydrolyses ferrienterobactin to DHBS

Class:Id	Reaction:9911599
_displayName	Fes hydrolyses ferrienterobactin to DHBS
_doRelease	TRUE
_timestamp	2025-05-21 07:41:31
authored	[InstanceEdit:9638337] Stephan, Ralf, 2019-02-21
catalystActivity	[CatalystActivity:9638417] enterochelin esterase activity of Fes [cytosol]
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:9911604] Stephan, Ralf, 2024-06-03
crossReference	[DatabaseIdentifier:9907523] RHEA:30112
disease	[Disease:3134792] bacterial infectious disease
edited	[InstanceEdit:9948470] Stephan, Ralf, 2025-05-21
input	[SimpleEntity:29356] H2O [cytosol] [SimpleEntity:29356] H2O [cytosol] [SimpleEntity:29356] H2O [cytosol] [SimpleEntity:9638381] FeEnt [cytosol] [SimpleEntity:70106] H+ [cytosol]
internalReviewed	[InstanceEdit:9915005] Gillespie, Marc E, 2024-07-02 [InstanceEdit:9917579] Gillespie, Marc E, 2024-08-08
isChimeric	FALSE
literatureReference	[LiteratureReference:9638423] Enterochelin system of iron transport in Escherichia coli: mutations affecting ferric-enterochelin esterase [LiteratureReference:9638339] Overexpression and purification of ferric enterobactin esterase from Escherichia coli. Demonstration of enzymatic hydrolysis of enterobactin and its iron complex
modified	[InstanceEdit:9911640] Stephan, Ralf, 2024-06-03 [InstanceEdit:9915006] Stephan, Ralf, 2024-07-02 [InstanceEdit:9915160] Stephan, Ralf, 2024-07-03 [InstanceEdit:9917580] Stephan, Ralf, 2024-08-08 [InstanceEdit:9931098] Stephan, Ralf, 2024-12-10 [InstanceEdit:9933047] Stephan, Ralf, 2024-12-23 [InstanceEdit:9948469] Stephan, Ralf, 2025-05-21
name	Fes hydrolyses ferrienterobactin to DHBS
output	[SimpleEntity:9907527] Fe(III)-DHBS [cytosol] [SimpleEntity:9638386] DHBS [cytosol] [SimpleEntity:9638386] DHBS [cytosol]
precedingEvent	[Reaction:9911603] FepC:FepD:FepG transports ferrienterobactin from the periplasmic space to the cytosol [Homo sapiens] [Reaction:9911597] Ferrienterobactin binds to FepB [Homo sapiens]
relatedSpecies	[Species:159879] Escherichia coli
releaseDate	2025-06-18
reviewStatus	[ReviewStatus:9821383] three stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9911615] R-HSA-9911599.1
summation	[Summation:9638416] Enterochelin esterase (Fes) hydrolyzes Fe3+-enterobactin, re...
(hasEvent)	[Pathway:9638334] Iron assimilation using enterobactin [Homo sapiens]
(replacementInstances)	[_Deleted:9911630] Deletion of instance: 9638397
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