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Details on Person Rora,b,c, Ep300, Ppargc1a bind Bmal1 (Arntl) gene

Class:IdReaction:9911575
_displayNameRora,b,c, Ep300, Ppargc1a bind Bmal1 (Arntl) gene
_doReleaseTRUE
_timestamp2025-02-18 21:11:51
authored[InstanceEdit:9911579] May, Bruce, 2024-06-01
compartment[Compartment:7660] nucleoplasm
created[InstanceEdit:9911579] May, Bruce, 2024-06-01
edited[InstanceEdit:9911579] May, Bruce, 2024-06-01
input[EntityWithAccessionedSequence:556805] Ep300 [nucleoplasm] [Mus musculus]
[EntityWithAccessionedSequence:556791] Ppargc1a [nucleoplasm] [Mus musculus]
[EntityWithAccessionedSequence:5663253] Arntl gene [nucleoplasm] [Mus musculus]
[DefinedSet:9911565] Rora,b,c [nucleoplasm] [Mus musculus]
internalReviewed[InstanceEdit:9936833] Matthews, Lisa, 2025-01-27
isChimericFALSE
literatureReference[LiteratureReference:1368104] RORalpha regulates the expression of genes involved in lipid homeostasis in skeletal muscle cells: caveolin-3 and CPT-1 are direct targets of ROR
[LiteratureReference:508661] Bidirectional role of orphan nuclear receptor RORalpha in clock gene transcriptions demonstrated by a novel reporter assay system
[LiteratureReference:508721] Differential control of Bmal1 circadian transcription by REV-ERB and ROR nuclear receptors
[LiteratureReference:508641] The orphan nuclear receptor RORalpha regulates circadian transcription of the mammalian core-clock Bmal1
[LiteratureReference:549438] A functional genomics strategy reveals Rora as a component of the mammalian circadian clock
[LiteratureReference:879778] A transcription factor response element for gene expression during circadian night
[LiteratureReference:9911573] RORĪ³ directly regulates the circadian expression of clock genes and downstream targets in vivo
modified[InstanceEdit:9931548] May, Bruce, 2024-12-12
[InstanceEdit:9932107] May, Bruce, 2024-12-17
[InstanceEdit:9933409] May, Bruce, 2024-12-29
[InstanceEdit:9935064] May, Bruce, 2025-01-12
[InstanceEdit:9936865] May, Bruce, 2025-01-27
[InstanceEdit:9938391] May, Bruce, 2025-02-14
[InstanceEdit:9938517] May, Bruce, 2025-02-17
[InstanceEdit:9938697] May, Bruce, 2025-02-18
nameRora,b,c, Ep300, Ppargc1a bind Bmal1 (Arntl) gene
output[Complex:9911567] Rora,b,c:Coactivator:Bmal1 gene (update) [nucleoplasm] [Mus musculus]
previousReviewStatus[ReviewStatus:9821383] three stars
releaseDate2025-03-26
reviewed[InstanceEdit:9938389] Sancar, Aziz, 2025-02-14
[InstanceEdit:9938694] Albrecht, Urs, 2025-02-18
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48892] Mus musculus
stableIdentifier[StableIdentifier:9911588] R-MMU-9911575.1
summation[Summation:9931511] Rora, Rorb, or Rorc binds two ROR responsive elements (RREs,...
(inferredFrom)[Reaction:9911560] RORA,B,C, EP300, PPARGC1A, NRIP1 bind BMAL1 (ARNTL) gene [Homo sapiens]
(replacementInstances)[_Deleted:9939528] Deletion of instance: 1368101
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No pathways have been reviewed or authored by Rora,b,c, Ep300, Ppargc1a bind Bmal1 (Arntl) gene (9911575)
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