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Details on Person KPC-2 hydrolyzes cephalothin

Class:IdReaction:9911515
_displayNameKPC-2 hydrolyzes cephalothin
_doReleaseTRUE
_timestamp2025-05-21 07:43:52
authored[InstanceEdit:9637715] Stephan, Ralf, 2019-02-19
catalystActivity[CatalystActivity:9638720] beta-lactamase activity of KPC-2 [cytosol]
compartment[Compartment:70101] cytosol
created[InstanceEdit:9911521] Stephan, Ralf, 2024-06-01
crossReference[DatabaseIdentifier:9909432] RHEA:20402
disease[Disease:3134792] bacterial infectious disease
edited[InstanceEdit:9948470] Stephan, Ralf, 2025-05-21
input[SimpleEntity:29356] H2O [cytosol]
[ChemicalDrug:9638906] cephalothin [cytosol]
internalReviewed[InstanceEdit:9915005] Gillespie, Marc E, 2024-07-02
[InstanceEdit:9917579] Gillespie, Marc E, 2024-08-08
isChimericFALSE
literatureReference[LiteratureReference:9638712] Carbapenem-resistant strain of Klebsiella oxytoca harboring carbapenem-hydrolyzing beta-lactamase KPC-2
modified[InstanceEdit:9911544] Stephan, Ralf, 2024-06-01
[InstanceEdit:9915006] Stephan, Ralf, 2024-07-02
[InstanceEdit:9917580] Stephan, Ralf, 2024-08-08
[InstanceEdit:9931098] Stephan, Ralf, 2024-12-10
[InstanceEdit:9933047] Stephan, Ralf, 2024-12-23
[InstanceEdit:9948469] Stephan, Ralf, 2025-05-21
nameKPC-2 hydrolyzes cephalothin
output[SimpleEntity:9638731] substituted β-amino acid [cytosol]
relatedSpecies[Species:9638647] Klebsiella pneumoniae
releaseDate2025-06-18
reviewStatus[ReviewStatus:9821383] three stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9911532] R-HSA-9911515.1
summation[Summation:9638738] In addition to penicillins and many cephalosporins, carbapen...
(hasEvent)[Pathway:9913143] Antimicrobial resistance [Homo sapiens]
(replacementInstances)[_Deleted:9911546] Deletion of instance: 9638692
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No pathways have been reviewed or authored by KPC-2 hydrolyzes cephalothin (9911515)