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Details on Person acrA:acrB:tolC transports azithromycin from the periplasm to the extracellular region

Class:Id	Reaction:9911305
_displayName	acrA:acrB:tolC transports azithromycin from the periplasm to the extracellular region
_timestamp	2024-05-28 08:26:03
catalystActivity	[CatalystActivity:9911306] porin activity of AcrA:AcrB:TolC [cell outer membrane]
compartment	[Compartment:1222638] periplasmic space [Compartment:20798] cell outer membrane [Compartment:984] extracellular region
created	[InstanceEdit:9911302] Stephan, Ralf, 2024-05-28
input	[ChemicalDrug:9911188] azithromycin [periplasmic space]
isChimeric	FALSE
literatureReference	[LiteratureReference:9639435] AcrA is a highly asymmetric protein capable of spanning the periplasm [LiteratureReference:9911195] Structure, Assembly, and Function of Tripartite Efflux and Type 1 Secretion Systems in Gram-Negative Bacteria
name	acrA:acrB:tolC transports azithromycin from the periplasm to the extracellular region
output	[ChemicalDrug:9639439] azithromycin [extracellular region]
precedingEvent	[Reaction:9639434] acrA:acrB:tolC transports azithromycin from the cytosol to the periplasm [Escherichia coli]
species	[Species:159879] Escherichia coli
stableIdentifier	[StableIdentifier:9911308] R-ECO-9911305.1
summation	[Summation:9911307] The tripartite efflux system acrA:acrB:tolC is the predomina...
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No pathways have been reviewed or authored by acrA:acrB:tolC transports azithromycin from the periplasm to the extracellular region (9911305)