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Details on Person ELANE cleaves NOTCH2NLA

Class:IdBlackBoxEvent:9911236
_displayNameELANE cleaves NOTCH2NLA
_doReleaseTRUE
_timestamp2024-10-24 17:44:19
authored[InstanceEdit:9911795] Orlic-Milacic, Marija, 2024-06-05
catalystActivity[CatalystActivity:9911491] serine-type endopeptidase activity of ELANE:NOTCH2NLA [extracellular region]
compartment[Compartment:984] extracellular region
created[InstanceEdit:9911235] Orlic-Milacic, Marija, 2024-05-27
edited[InstanceEdit:9925757] Orlic-Milacic, Marija, 2024-10-23
input[Complex:9911480] ELANE:NOTCH2NLA [extracellular region] [Homo sapiens]
internalReviewed[InstanceEdit:9919303] Matthews, Lisa, 2024-06-17
isChimericFALSE
literatureReference[LiteratureReference:9911328] A novel notch protein, N2N, targeted by neutrophil elastase and implicated in hereditary neutropenia
modified[InstanceEdit:9911333] Orlic-Milacic, Marija, 2024-05-28
[InstanceEdit:9911497] Orlic-Milacic, Marija, 2024-05-31
[InstanceEdit:9919306] Orlic-Milacic, Marija, 2024-08-20
[InstanceEdit:9925743] Orlic-Milacic, Marija, 2024-10-22
[InstanceEdit:9925767] Orlic-Milacic, Marija, 2024-10-24
nameELANE cleaves NOTCH2NLA
output[EntityWithAccessionedSequence:1602474] ELANE [extracellular region] [Homo sapiens]
[EntityWithAccessionedSequence:9911493] NOTCH2NLA(1-?) [extracellular region] [Homo sapiens]
[EntityWithAccessionedSequence:9911490] NOTCH2NLA(?-236) [extracellular region] [Homo sapiens]
precedingEvent
previousReviewStatus[ReviewStatus:9821383] three stars
releaseDate2024-12-04
reviewed[InstanceEdit:9925739] Heide, Michael, 2024-10-25
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9911238] R-HSA-9911236.1
structureModified[InstanceEdit:9911497] Orlic-Milacic, Marija, 2024-05-31
summation[Summation:9911492]

ELANE (also known as ELA2 or NE), a human neutrophil elas...

(hasEvent)[Pathway:9911233] Expression of NOTCH2NL genes [Homo sapiens]
(precedingEvent)[NegativePrecedingEvent:9911794] Futile Cycle: ELANE cleaves NOTCH2NLA
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No pathways have been reviewed or authored by ELANE cleaves NOTCH2NLA (9911236)