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Details on Person Definitive endoderm cell produces dorsal foregut endoderm cell

Class:Id	CellDevelopmentStep:9911210
_displayName	Definitive endoderm cell produces dorsal foregut endoderm cell
_doRelease	TRUE
_timestamp	2024-11-04 15:47:30
authored	[InstanceEdit:9925562] Orlic-Milacic, Marija, 2024-10-17
created	[InstanceEdit:9911209] Orlic-Milacic, Marija, 2024-05-27
edited	[InstanceEdit:9926782] Orlic-Milacic, Marija, 2024-11-04
input	[Cell:9911207] definitive endoderm cell [Homo sapiens]
internalReviewed	[InstanceEdit:9926066] May, Bruce, 2024-10-28
isChimeric	FALSE
literatureReference	[LiteratureReference:9921765] FGF2 specifies hESC-derived definitive endoderm into foregut/midgut cell lineages in a concentration-dependent manner [LiteratureReference:9921554] FGF4 and retinoic acid direct differentiation of hESCs into PDX1-expressing foregut endoderm in a time- and concentration-dependent manner [LiteratureReference:9909322] Development of the human pancreas from foregut to endocrine commitment
modified	[InstanceEdit:9921634] Orlic-Milacic, Marija, 2024-09-12 [InstanceEdit:9921767] Orlic-Milacic, Marija, 2024-09-13 [InstanceEdit:9921784] Orlic-Milacic, Marija, 2024-09-13 [InstanceEdit:9921975] Orlic-Milacic, Marija, 2024-09-17 [InstanceEdit:9921977] Orlic-Milacic, Marija, 2024-09-17 [InstanceEdit:9926901] Orlic-Milacic, Marija, 2024-11-04
name	Definitive endoderm cell produces dorsal foregut endoderm cell
output	[Cell:9907637] dorsal foregut endoderm cell [Homo sapiens]
precedingEvent	[CellDevelopmentStep:9911208] Definitive endoderm cell produces ventral foregut endoderm cell [Homo sapiens]
previousReviewStatus	[ReviewStatus:9821383] three stars
regulatedBy	[PositiveRegulation:9757507] Positive regulation by 'FGF2(10-155) [extracellular region]' [PositiveRegulation:9921563] Positive regulation by 'FGF4 [extracellular region]' [PositiveRegulation:9921566] Positive regulation by 'atRA [extracellular region]'
releaseDate	2024-12-04
requiredInputComponent	[EntityWithAccessionedSequence:446178] RARB [nucleoplasm] [Homo sapiens]
reviewed	[InstanceEdit:9926069] Li, Nancy T, 2024-10-30
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9911223] R-HSA-9911210.1
structureModified	[InstanceEdit:9921634] Orlic-Milacic, Marija, 2024-09-12 [InstanceEdit:9921767] Orlic-Milacic, Marija, 2024-09-13 [InstanceEdit:9921784] Orlic-Milacic, Marija, 2024-09-13
summation	[Summation:9921754] The formation of foregut endoderm cells from definitive e...
(hasEvent)	[CellLineagePath:9937080] Developmental Lineage of Multipotent Pancreatic Progenitor Cells [Homo sapiens]
(precedingEvent)	[CellDevelopmentStep:9909325] Dorsal foregut endoderm cell produces duodeno-pancreatic endoderm cell [Homo sapiens]
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No pathways have been reviewed or authored by Definitive endoderm cell produces dorsal foregut endoderm cell (9911210)