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Details on Person definitive endoderm cell

Class:Id	Cell:9911207
_displayName	definitive endoderm cell
_timestamp	2024-11-11 21:53:24
cellType	[CellType:9907635] endodermal cell
created	[InstanceEdit:9911209] Orlic-Milacic, Marija, 2024-05-27
markerReference	[MarkerReference:9921110] CER1 [exocytic vesicle] Secreted cerberus1 as a marker for quantification of definitive endoderm differentiation of the pluripotent stem cells [MarkerReference:9921127] CER1 mRNA [cytosol] Efficient differentiation of human embryonic stem cells to definitive endoderm [MarkerReference:9921104] CXCR4 [plasma membrane] Efficient differentiation of human embryonic stem cells to definitive endoderm [MarkerReference:9921134] CXCR4 mRNA [cytosol] Efficient differentiation of human embryonic stem cells to definitive endoderm [MarkerReference:9921105] FOXA2 [nucleoplasm] Efficient differentiation of human embryonic stem cells to definitive endoderm [MarkerReference:9921146] FOXA2 mRNA [cytosol] Efficient differentiation of human embryonic stem cells to definitive endoderm [MarkerReference:9921404] FOXA3 mRNA [cytosol] Activin and BMP4 synergistically promote formation of definitive endoderm in human embryonic stem cells [MarkerReference:9921357] GATA4 [nucleoplasm] Establishment of endoderm progenitors by SOX transcription factor expression in human embryonic stem cells [MarkerReference:9921350] GATA4 mRNA [cytosol] Establishment of endoderm progenitors by SOX transcription factor expression in human embryonic stem cells [MarkerReference:9927540] GATA6 [nucleoplasm] GATA6 is essential for endoderm formation from human pluripotent stem cells [MarkerReference:9921351] GATA6 mRNA [cytosol] Establishment of endoderm progenitors by SOX transcription factor expression in human embryonic stem cells [MarkerReference:9921420] GSC mRNA [cytosol] Efficient differentiation of human embryonic stem cells to definitive endoderm [MarkerReference:9921434] HHEX mRNA [cytosol] Efficient and directive generation of two distinct endoderm lineages from human ESCs and iPSCs by differentiation stage-specific SOX17 transduction [MarkerReference:9921377] HNF4A mRNA [cytosol] Establishment of endoderm progenitors by SOX transcription factor expression in human embryonic stem cells [MarkerReference:9921432] LEFTY1 mRNA [cytosol] Single-Cell RNA-Sequencing-Based CRISPRi Screening Resolves Molecular Drivers of Early Human Endoderm Development [MarkerReference:9921438] MIXL1 mRNA [cytosol] Efficient differentiation of human embryonic stem cells to definitive endoderm [MarkerReference:9921367] SOX17 [nucleoplasm] Efficient differentiation of human embryonic stem cells to definitive endoderm [MarkerReference:9921361] SOX17 mRNA [cytosol] Efficient differentiation of human embryonic stem cells to definitive endoderm [MarkerReference:9921436] OTX2 mRNA [cytosol] Distinct gene expression signatures in human embryonic stem cells differentiated towards definitive endoderm at single-cell level
modified	[InstanceEdit:9921145] Orlic-Milacic, Marija, 2024-09-05 [InstanceEdit:9921148] Orlic-Milacic, Marija, 2024-09-05 [InstanceEdit:9921356] Orlic-Milacic, Marija, 2024-09-09 [InstanceEdit:9921360] Orlic-Milacic, Marija, 2024-09-09 [InstanceEdit:9921375] Orlic-Milacic, Marija, 2024-09-09 [InstanceEdit:9921381] Orlic-Milacic, Marija, 2024-09-09 [InstanceEdit:9921406] Orlic-Milacic, Marija, 2024-09-09 [InstanceEdit:9921429] Orlic-Milacic, Marija, 2024-09-09 [InstanceEdit:9921444] Orlic-Milacic, Marija, 2024-09-09 [InstanceEdit:9927544] Orlic-Milacic, Marija, 2024-11-07 [InstanceEdit:9928160] Orlic-Milacic, Marija, 2024-11-11
name	definitive endoderm cell
proteinMarker	[EntityWithAccessionedSequence:9921118] CER1 [exocytic vesicle] [Homo sapiens] [EntityWithAccessionedSequence:2980772] CXCR4 [plasma membrane] [Homo sapiens] [EntityWithAccessionedSequence:211275] FOXA2 [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:400553] GATA4 [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:452902] GATA6 [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:5625834] SOX17 [nucleoplasm] [Homo sapiens]
RNAMarker	[EntityWithAccessionedSequence:9921130] CER1 mRNA [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:9921116] CXCR4 mRNA [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:9921122] FOXA2 mRNA [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:9921400] FOXA3 mRNA [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:9921346] GATA4 mRNA [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:9921354] GATA6 mRNA [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:9921422] GSC mRNA [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:9915042] HHEX mRNA [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:9921379] HNF4A mRNA [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:9921439] LEFTY1 mRNA [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:9921435] MIXL1 mRNA [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:9921433] OTX2 mRNA [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:9921364] SOX17 mRNA [cytosol] [Homo sapiens]
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9911222] R-HSA-9911207.1
tissue	[Anatomy:9928158] endoderm
(cell)	[MarkerReference:9921104] CXCR4 [plasma membrane] Efficient differentiation of human embryonic stem cells to definitive endoderm [MarkerReference:9921105] FOXA2 [nucleoplasm] Efficient differentiation of human embryonic stem cells to definitive endoderm [MarkerReference:9921110] CER1 [exocytic vesicle] Secreted cerberus1 as a marker for quantification of definitive endoderm differentiation of the pluripotent stem cells [MarkerReference:9921127] CER1 mRNA [cytosol] Efficient differentiation of human embryonic stem cells to definitive endoderm [MarkerReference:9921134] CXCR4 mRNA [cytosol] Efficient differentiation of human embryonic stem cells to definitive endoderm [MarkerReference:9921146] FOXA2 mRNA [cytosol] Efficient differentiation of human embryonic stem cells to definitive endoderm [MarkerReference:9921350] GATA4 mRNA [cytosol] Establishment of endoderm progenitors by SOX transcription factor expression in human embryonic stem cells [MarkerReference:9921351] GATA6 mRNA [cytosol] Establishment of endoderm progenitors by SOX transcription factor expression in human embryonic stem cells [MarkerReference:9921357] GATA4 [nucleoplasm] Establishment of endoderm progenitors by SOX transcription factor expression in human embryonic stem cells [MarkerReference:9921361] SOX17 mRNA [cytosol] Efficient differentiation of human embryonic stem cells to definitive endoderm List all 19 refering instances
(input)	[CellDevelopmentStep:9911208] Definitive endoderm cell produces ventral foregut endoderm cell [Homo sapiens] [CellDevelopmentStep:9911210] Definitive endoderm cell produces dorsal foregut endoderm cell [Homo sapiens] [CellDevelopmentStep:9911214] Definitive endoderm cell produces ventral foregut endoderm cell [Homo sapiens]
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No pathways have been reviewed or authored by definitive endoderm cell (9911207)