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Details on Person Clone of 5205682 Parkin promotes the ubiquitination of mitochondrial substrates, that is replaced by 9834070

Class:IdReaction:9910582
_displayNameClone of 5205682 Parkin promotes the ubiquitination of mitochondrial substrates, that is replaced by 9834070
_timestamp2024-05-15 20:06:35
catalystActivity[CatalystActivity:5205689] ubiquitin-protein transferase activity of PRKN:PINK1 [mitochondrial outer membrane]
compartment[Compartment:17906] mitochondrial outer membrane
created[InstanceEdit:9910583] Shamovsky, Veronica, 2024-05-15
input[EntityWithAccessionedSequence:1267988] VDAC1 [mitochondrial outer membrane] [Homo sapiens]
[EntityWithAccessionedSequence:5205688] MTERFD1 [mitochondrial outer membrane] [Homo sapiens]
[EntityWithAccessionedSequence:992745] MFN1 [mitochondrial outer membrane] [Homo sapiens]
[EntityWithAccessionedSequence:992714] MFN2 [mitochondrial outer membrane] [Homo sapiens]
[DefinedSet:113595] Ub [cytosol] [Homo sapiens]
[DefinedSet:113595] Ub [cytosol] [Homo sapiens]
[DefinedSet:113595] Ub [cytosol] [Homo sapiens]
[DefinedSet:113595] Ub [cytosol] [Homo sapiens]
[DefinedSet:113595] Ub [cytosol] [Homo sapiens]
[DefinedSet:113595] Ub [cytosol] [Homo sapiens]
[DefinedSet:113595] Ub [cytosol] [Homo sapiens]
[DefinedSet:113595] Ub [cytosol] [Homo sapiens]
[DefinedSet:113595] Ub [cytosol] [Homo sapiens]
[DefinedSet:113595] Ub [cytosol] [Homo sapiens]
[DefinedSet:113595] Ub [cytosol] [Homo sapiens]
[DefinedSet:113595] Ub [cytosol] [Homo sapiens]
isChimericFALSE
literatureReference[LiteratureReference:5205654] Mitochondrial accumulation of polyubiquitinated proteins and differential regulation of apoptosis by polyubiquitination sites Lys-48 and -63
nameClone of 5205682 Parkin promotes the ubiquitination of mitochondrial substrates, that is replaced by 9834070
output[EntityWithAccessionedSequence:5205630] K48polyUb-MTERFD1 [mitochondrial outer membrane] [Homo sapiens]
[EntityWithAccessionedSequence:5205624] K48polyUb-VDAC1 [mitochondrial outer membrane] [Homo sapiens]
[EntityWithAccessionedSequence:5205679] K48polyUb-MFN1 [mitochondrial outer membrane] [Homo sapiens]
[EntityWithAccessionedSequence:5205668] K48polyUb-MFN2 [mitochondrial outer membrane] [Homo sapiens]
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9910585] R-HSA-9910582.1
summation[Summation:9910580] This events is a clone of 5* event of 'Parkin promotes the u...
(hasEvent)[Pathway:5205685] PINK1-PRKN Mediated Mitophagy [Homo sapiens]
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No pathways have been reviewed or authored by Clone of 5205682 Parkin promotes the ubiquitination of mitochondrial substrates, that is replaced by 9834070 (9910582)