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Details on Person AP-1 binding to CD274 gene

Class:Id	Reaction:9909610
_displayName	AP-1 binding to CD274 gene
_doRelease	TRUE
_timestamp	2025-08-26 07:55:56
authored	[InstanceEdit:9964122] Hung, Mien-Chie, Yamaguchi, Hirohito, 2025-08-26 [InstanceEdit:9927358] Tiwari, Krishna, 2024-11-05
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9909599] Tiwari, Krishna, 2024-05-14
edited	[InstanceEdit:9962761] Gillespie, Marc E, 2025-08-08
input	[EntityWithAccessionedSequence:9701419] CD274 gene [nucleoplasm] [Homo sapiens] [CandidateSet:9909605] AP-1 [nucleoplasm] [Homo sapiens]
internalReviewed	[InstanceEdit:9914713] D'Eustachio, Peter, 2024-06-26
isChimeric	FALSE
literatureReference	[LiteratureReference:9911992] Constitutive AP-1 activity and EBV infection induce PD-L1 in Hodgkin lymphomas and posttransplant lymphoproliferative disorders: implications for targeted therapy [LiteratureReference:9911838] RAS-Mitogen-Activated Protein Kinase Signal Is Required for Enhanced PD-L1 Expression in Human Lung Cancers
modified	[InstanceEdit:9909704] Tiwari, Krishna, 2024-05-14 [InstanceEdit:9911970] Tiwari, Krishna, 2024-06-06 [InstanceEdit:9918017] Tiwari, Krishna, 2024-08-14 [InstanceEdit:9929193] Tiwari, Krishna, 2024-11-21 [InstanceEdit:9963582] Gillespie, Marc E, 2025-08-14 [InstanceEdit:9964108] Gillespie, Marc E, 2025-08-19 [InstanceEdit:9964110] Gillespie, Marc E, 2025-08-19 [InstanceEdit:9964120] Gillespie, Marc E, 2025-08-19 [InstanceEdit:9964121] Gillespie, Marc E, 2025-08-19 [InstanceEdit:9964125] Gillespie, Marc E, 2025-08-19 [InstanceEdit:9965199] Matthews, Lisa, 2025-08-26
name	AP-1 binding to CD274 gene
output	[Complex:9909601] AP-1:CD274 gene [nucleoplasm] [Homo sapiens]
precedingEvent	[Reaction:450292] Formation of Activated Protein 1 (AP-1) complex. cFOS/c-JUN heterodimer. [Homo sapiens] [Reaction:168136] Activated JNKs phosphorylate c-JUN [Homo sapiens] [Reaction:450325] c-FOS activation by phospho ERK1/2 [Homo sapiens]
previousReviewStatus	[ReviewStatus:9821383] three stars
releaseDate	2025-09-18
reviewed	[InstanceEdit:9964122] Hung, Mien-Chie, Yamaguchi, Hirohito, 2025-08-26
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9909695] R-HSA-9909610.1
structureModified	[InstanceEdit:9918017] Tiwari, Krishna, 2024-08-14
summation	[Summation:9911967] AP-1 (Activator Protein-1, a heterodimer of FOS and JUN fami...
(hasEvent)	[Pathway:9909649] Regulation of PD-L1(CD274) transcription [Homo sapiens]
(precedingEvent)	[BlackBoxEvent:9909623] CD274 Transcription [Homo sapiens]
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No pathways have been reviewed or authored by AP-1 binding to CD274 gene (9909610)