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Details on Person Negative gene expression regulation by 'BHLHE40 dimer [nucleoplasm]'

Class:Id	NegativeGeneExpressionRegulation:9909568
_displayName	Negative gene expression regulation by 'BHLHE40 dimer [nucleoplasm]'
_timestamp	2024-05-14 04:45:10
activity	[GO_MolecularFunction:2266139] DNA-binding transcription repressor activity, RNA polymerase II-specific
created	[InstanceEdit:9909554] May, Bruce, 2024-05-14
regulator	[Complex:9909555] BHLHE40 dimer [nucleoplasm] [Homo sapiens]
(regulatedBy)	[BlackBoxEvent:879770] Expression of DEC2 (BHLHE41, BHLHB3) [Homo sapiens] [BlackBoxEvent:879798] Expression of DEC1 (BHLHE40, BHLHB2) [Homo sapiens] [BlackBoxEvent:9909561] Phosphorylated BMAL1:CLOCK,NPAS2 and coactivators positively regulate expression of Period-1 (PER1) [Homo sapiens] [BlackBoxEvent:9909566] Expression of DEC2 (BHLHE41, BHLHB3) (update) [Homo sapiens] [BlackBoxEvent:9909567] Expression of DEC1 (BHLHE40, BHLHB2) (update) [Homo sapiens]
(regulation)	[RegulationReference:9909559] Negative gene expression regulation by 'BHLHE40 dimer [nucleoplasm]' DEC1 negatively regulates the expression of DEC2 through binding to the E-box in the proximal promoter [RegulationReference:9909562] Negative gene expression regulation by 'BHLHE40 dimer [nucleoplasm]' Functional analysis of the basic helix-loop-helix transcription factor DEC1 in circadian regulation. Interaction with BMAL1
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No pathways have been reviewed or authored by Negative gene expression regulation by 'BHLHE40 dimer [nucleoplasm]' (9909568)