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Details on Person Formation of Cry:Per:Kinase complex

Class:Id	BlackBoxEvent:9909360
_displayName	Formation of Cry:Per:Kinase complex
_doRelease	TRUE
_timestamp	2025-02-18 21:04:57
authored	[InstanceEdit:9909380] May, Bruce, 2024-05-13
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:9909380] May, Bruce, 2024-05-13
edited	[InstanceEdit:9909380] May, Bruce, 2024-05-13
input	[DefinedSet:508702] Csnk1d,Csnk1e [cytosol] [Mus musculus] [EntityWithAccessionedSequence:508663] Per1 [cytosol] [Mus musculus] [EntityWithAccessionedSequence:508621] Per2 [cytosol] [Mus musculus] [EntityWithAccessionedSequence:9909383] Per3 [cytosol] [Mus musculus] [EntityWithAccessionedSequence:508637] Cry1 [cytosol] [Mus musculus] [EntityWithAccessionedSequence:508614] Cry2 [cytosol] [Mus musculus]
internalReviewed	[InstanceEdit:9936833] Matthews, Lisa, 2025-01-27
isChimeric	FALSE
literatureReference	[LiteratureReference:549540] mCRY1 and mCRY2 are essential components of the negative limb of the circadian clock feedback loop [LiteratureReference:508611] Essential roles of CKIdelta and CKIepsilon in the mammalian circadian clock [LiteratureReference:508630] Nuclear entry of the circadian regulator mPER1 is controlled by mammalian casein kinase I epsilon [LiteratureReference:508629] Direct association between mouse PERIOD and CKIepsilon is critical for a functioning circadian clock [LiteratureReference:421281] The circadian regulatory proteins BMAL1 and cryptochromes are substrates of casein kinase Iepsilon [LiteratureReference:5663106] Molecular assembly of the period-cryptochrome circadian transcriptional repressor complex [LiteratureReference:9909363] Macromolecular Assemblies of the Mammalian Circadian Clock [LiteratureReference:9909390] Analysis of mammalian circadian clock protein complexes over a circadian cycle [LiteratureReference:9920677] Cyclin-dependent kinase 5 (CDK5) regulates the circadian clock [LiteratureReference:549411] Analysis of clock proteins in mouse SCN demonstrates phylogenetic divergence of the circadian clockwork and resetting mechanisms [LiteratureReference:879801] Light-independent role of CRY1 and CRY2 in the mammalian circadian clock
modified	[InstanceEdit:9920763] May, Bruce, 2024-09-03 [InstanceEdit:9930079] May, Bruce, 2024-12-02 [InstanceEdit:9933409] May, Bruce, 2024-12-29 [InstanceEdit:9935064] May, Bruce, 2025-01-12 [InstanceEdit:9936865] May, Bruce, 2025-01-27 [InstanceEdit:9938453] May, Bruce, 2025-02-14 [InstanceEdit:9938517] May, Bruce, 2025-02-17 [InstanceEdit:9938697] May, Bruce, 2025-02-18
name	Formation of Cry:Per:Kinase complex
output	[Complex:9909387] Cry1:Cry2:Per1:Per2:Per3:Csnk1e,Csnk1d [cytosol] [Mus musculus]
previousReviewStatus	[ReviewStatus:9821383] three stars
releaseDate	2025-03-26
reviewed	[InstanceEdit:9938389] Sancar, Aziz, 2025-02-14 [InstanceEdit:9938694] Albrecht, Urs, 2025-02-18
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48892] Mus musculus
stableIdentifier	[StableIdentifier:9909421] R-MMU-9909360.1
summation	[Summation:9930074] Cryptochrome (Cry1, Cry2) proteins, Period (Per1, Per2, Per3...
(inferredFrom)	[BlackBoxEvent:9909392] Formation of CRY:PER:Kinase complex [Homo sapiens]
(replacementInstances)	[_Deleted:9939516] Deletion of instance: 1856952
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No pathways have been reviewed or authored by Formation of Cry:Per:Kinase complex (9909360)