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Details on Person primary multipotent pancreatic progenitor cell

Class:Id	Cell:9909323
_displayName	primary multipotent pancreatic progenitor cell
_timestamp	2024-11-11 21:59:15
cellType	[CellType:9909343] progenitor cell
created	[InstanceEdit:9909311] Orlic-Milacic, Marija, 2024-05-07
markerReference	[MarkerReference:9909338] FOXA2 [nucleoplasm] FGF4 and retinoic acid direct differentiation of hESCs into PDX1-expressing foregut endoderm in a time- and concentration-dependent manner [MarkerReference:9921561] FOXA2 mRNA [cytosol] FGF4 and retinoic acid direct differentiation of hESCs into PDX1-expressing foregut endoderm in a time- and concentration-dependent manner [MarkerReference:9922028] GATA4 [nucleoplasm] Development of the human pancreas from foregut to endocrine commitment [MarkerReference:9922014] GATA4 mRNA [cytosol] Charting cellular identity during human in vitro β-cell differentiation [MarkerReference:9922006] GATA6 mRNA [cytosol] TEAD and YAP regulate the enhancer network of human embryonic pancreatic progenitors [MarkerReference:9922044] HNF1B [nucleoplasm] Modeling HNF1B-associated monogenic diabetes using human iPSCs reveals an early stage impairment of the pancreatic developmental program [MarkerReference:9922032] HNF1B mRNA [cytosol] TEAD and YAP regulate the enhancer network of human embryonic pancreatic progenitors [MarkerReference:9909341] NKX6-1 [nucleoplasm] Development of the human pancreas from foregut to endocrine commitment [MarkerReference:9922029] NKX6-1 mRNA [cytosol] The Role of ARX in Human Pancreatic Endocrine Specification [MarkerReference:9921636] ONECUT1 [nucleoplasm] FGF4 and retinoic acid direct differentiation of hESCs into PDX1-expressing foregut endoderm in a time- and concentration-dependent manner [MarkerReference:9921578] ONECUT1 mRNA [cytosol] FGF4 and retinoic acid direct differentiation of hESCs into PDX1-expressing foregut endoderm in a time- and concentration-dependent manner [MarkerReference:9909340] PDX1 [nucleoplasm] Development of the human pancreas from foregut to endocrine commitment [MarkerReference:9921550] PDX1 mRNA [cytosol] FGF4 and retinoic acid direct differentiation of hESCs into PDX1-expressing foregut endoderm in a time- and concentration-dependent manner [MarkerReference:9922040] PTF1A mRNA [cytosol] TEAD and YAP regulate the enhancer network of human embryonic pancreatic progenitors [MarkerReference:9909342] SOX9 [nucleoplasm] Development of the human pancreas from foregut to endocrine commitment [MarkerReference:9921564] SOX9 mRNA [cytosol] FGF4 and retinoic acid direct differentiation of hESCs into PDX1-expressing foregut endoderm in a time- and concentration-dependent manner
modified	[InstanceEdit:9909344] Orlic-Milacic, Marija, 2024-05-10 [InstanceEdit:9921939] Orlic-Milacic, Marija, 2024-09-14 [InstanceEdit:9922036] Orlic-Milacic, Marija, 2024-09-18 [InstanceEdit:9922037] Orlic-Milacic, Marija, 2024-09-18 [InstanceEdit:9922043] Orlic-Milacic, Marija, 2024-09-18 [InstanceEdit:9922053] Orlic-Milacic, Marija, 2024-09-18 [InstanceEdit:9928165] Orlic-Milacic, Marija, 2024-11-11
name	primary multipotent pancreatic progenitor cell
proteinMarker	[EntityWithAccessionedSequence:211275] FOXA2 [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:400553] GATA4 [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:3004721] HNF1B [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:210765] NKX6-1 [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:210782] ONECUT1 [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:211179] PDX1 [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:3214954] SOX9 [nucleoplasm] [Homo sapiens]
RNAMarker	[EntityWithAccessionedSequence:9921122] FOXA2 mRNA [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:9921346] GATA4 mRNA [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:9921354] GATA6 mRNA [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:9922017] HNF1B mRNA [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:9922021] NKX6-1 mRNA [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:9921574] ONECUT1 mRNA [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:9921553] PDX1 mRNA [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:9922038] PTF1A mRNA [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:9921562] SOX9 mRNA [cytosol] [Homo sapiens]
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9909327] R-HSA-9909323.1
tissue	[Anatomy:9928163] pancreatic epithelial bud
(cell)	[MarkerReference:9909338] FOXA2 [nucleoplasm] FGF4 and retinoic acid direct differentiation of hESCs into PDX1-expressing foregut endoderm in a time- and concentration-dependent manner [MarkerReference:9909340] PDX1 [nucleoplasm] Development of the human pancreas from foregut to endocrine commitment [MarkerReference:9909341] NKX6-1 [nucleoplasm] Development of the human pancreas from foregut to endocrine commitment [MarkerReference:9909342] SOX9 [nucleoplasm] Development of the human pancreas from foregut to endocrine commitment [MarkerReference:9921550] PDX1 mRNA [cytosol] FGF4 and retinoic acid direct differentiation of hESCs into PDX1-expressing foregut endoderm in a time- and concentration-dependent manner [MarkerReference:9921561] FOXA2 mRNA [cytosol] FGF4 and retinoic acid direct differentiation of hESCs into PDX1-expressing foregut endoderm in a time- and concentration-dependent manner [MarkerReference:9921564] SOX9 mRNA [cytosol] FGF4 and retinoic acid direct differentiation of hESCs into PDX1-expressing foregut endoderm in a time- and concentration-dependent manner [MarkerReference:9921578] ONECUT1 mRNA [cytosol] FGF4 and retinoic acid direct differentiation of hESCs into PDX1-expressing foregut endoderm in a time- and concentration-dependent manner [MarkerReference:9921636] ONECUT1 [nucleoplasm] FGF4 and retinoic acid direct differentiation of hESCs into PDX1-expressing foregut endoderm in a time- and concentration-dependent manner [MarkerReference:9922006] GATA6 mRNA [cytosol] TEAD and YAP regulate the enhancer network of human embryonic pancreatic progenitors List all 16 refering instances
(input)	[CellDevelopmentStep:9909347] Primary multipotent pancreatic progenitor cell produces pancreatic tip progenitor cell [Homo sapiens] [CellDevelopmentStep:9910607] Primary multipotent pancreatic progenitor cell produces trunk bipotent pancreatic progenitor cell [Homo sapiens]
(output)	[CellDevelopmentStep:9909305] Duodeno-pancreatic endoderm cell produces primary multipotent pancreatic progenitor cell [Homo sapiens] [CellDevelopmentStep:9911206] Hepato-pancreatic endoderm cell produces primary multipotent pancreatic progenitor cell [Homo sapiens] [CellDevelopmentStep:9911215] Ventral foregut endoderm cell produces primary multipotent pancreatic progenitor cell [Homo sapiens]
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No pathways have been reviewed or authored by primary multipotent pancreatic progenitor cell (9909323)