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Details on Person HK1 phosphorylates Mannose to Man6P

Class:Id	Reaction:9909159
_displayName	HK1 phosphorylates Mannose to Man6P
_doRelease	TRUE
_timestamp	2024-05-21 17:11:19
authored	[InstanceEdit:9909163] D'Eustachio, Peter, 2024-04-29
catalystActivity	[CatalystActivity:9909168] mannokinase activity of HK1 [cytosol]
catalystActivityReference	[CatalystActivityReference:9909171] mannokinase activity of HK1 [cytosol] EFFECT OF DIETARY CARBOHYDRATE AND GLUCOKINASE AND MANNOKINASE ACTIVITIES OF VARIOUS RAT TISSUES
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:9909163] D'Eustachio, Peter, 2024-04-29
crossReference	[DatabaseIdentifier:9909170] RHEA:11029
edited	[InstanceEdit:9909163] D'Eustachio, Peter, 2024-04-29
input	[SimpleEntity:113592] ATP [cytosol] [SimpleEntity:429579] Man [cytosol]
internalReviewed	[InstanceEdit:9909162] D'Eustachio, Peter, 2024-04-29
isChimeric	FALSE
literatureReference	[LiteratureReference:9909166] Mannose metabolism and the demonstration of mannokinase and phosphomannoisomerase activities in the lactating rat mammary gland [LiteratureReference:9909165] EFFECT OF DIETARY CARBOHYDRATE AND GLUCOKINASE AND MANNOKINASE ACTIVITIES OF VARIOUS RAT TISSUES
modified	[InstanceEdit:9909178] D'Eustachio, Peter, 2024-04-29 [InstanceEdit:9910565] D'Eustachio, Peter, 2024-05-15 [InstanceEdit:9910842] D'Eustachio, Peter, 2024-05-21
name	HK1 phosphorylates Mannose to Man6P ATP + D-mannose => ADP + D-mannose 6-phosphate + H(+)
output	[SimpleEntity:29370] ADP [cytosol] [SimpleEntity:70106] H+ [cytosol] [SimpleEntity:532562] Man6P [cytosol]
precedingEvent	[Reaction:429567] Co-transport (influx) of glucose/mannose and Na+ ions by SGLT4 [Homo sapiens] [Reaction:8876283] SLC5A10 cotransports Na+ with Man, Fru from extracellular region to cytosol [Homo sapiens]
previousReviewStatus	[ReviewStatus:9821383] three stars
releaseDate	2024-06-15
reviewed	[InstanceEdit:9910566] Hill, David P, 2024-05-15
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9909177] R-HSA-9909159.1
summation	[Summation:9909164] Cytosolic hexokinase 1 (HK1) catalyzes the phosphorylation o...
(hasEvent)	[Pathway:446205] Synthesis of GDP-mannose [Homo sapiens]
(precedingEvent)	[Reaction:446201] PMM1,2 isomerise Man6P to Man1P [Homo sapiens]
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No pathways have been reviewed or authored by HK1 phosphorylates Mannose to Man6P (9909159)