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Details on Person Based on a mouse study, the outer ring of the spermatoprotea...

Class:IdSummation:9908782
_displayNameBased on a mouse study, the outer ring of the spermatoprotea...
_timestamp2024-04-24 03:44:40
created[InstanceEdit:9908788] Orlic-Milacic, Marija, 2024-04-23
literatureReference[LiteratureReference:9908754] Characterization of the testis-specific proteasome subunit α4s in mammals
[LiteratureReference:9908766] Proteasome complexes experience profound structural and functional rearrangements throughout mammalian spermatogenesis
modified[InstanceEdit:9908906] Orlic-Milacic, Marija, 2024-04-24
textBased on a mouse study, the outer ring of the spermatoproteasome 20S core particle (20S sCP), whose alpha-4 (PSMA7) subunit is replaced with the spermatoproteasome-specific subunit alpha-4s (PSMA8), interacts with the inner beta ring composed of canonical beta subunits (Uechi et al. 2014). As the role of the PSMG1:PSMG2 complex in the context of spermatoproteasome has not been examined and as spermatoproteasomes were shown to interact with significantly less POMP than canonical proteasomes (Zivkovic et al. 2022: bovine model system), these three proteins are not shown as components of half-spermatoproteasomes.
(summation)[BlackBoxEvent:9908775] Formation of the inner ring of the 20S spermatoproteasome core particle [Homo sapiens]
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