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Details on Person Formation of the Spliceosomal E complex containing Alternative Splicing Factor

Class:Id	BlackBoxEvent:9908308
_displayName	Formation of the Spliceosomal E complex containing Alternative Splicing Factor
_timestamp	2024-04-20 21:23:38
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9908293] May, Bruce, 2024-04-20
input	[Complex:71917] U1 snRNP [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:53517] DHX9 [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:72043] SUGP1 [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:3900136] DDX5 [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:6814858] SRRT [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:8865928] SF1 [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:8867890] PRPF40A [nucleoplasm] [Homo sapiens] [Complex:9770256] U2AF [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:9770250] RBM25 [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:9770254] RBM39 [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:8985564] RBM7 [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:9770258] LUC7L3 [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:9770246] HTATSF1 [nucleoplasm] [Homo sapiens] [EntityWithAccessionedSequence:8865888] SRRM2 [nucleoplasm] [Homo sapiens] [DefinedSet:9908313] Alternative Splicing Factor:pre-mRNA:CBC: RNA pol II [nucleoplasm] [Homo sapiens]
literatureReference	[LiteratureReference:72109] Protein composition of human prespliceosomes isolated by a tobramycin affinity-selection method. [LiteratureReference:72117] Large-scale proteomic analysis of the human spliceosome. [LiteratureReference:8850757] Functional mammalian spliceosomal complex E contains SMN complex proteins in addition to U1 and U2 snRNPs [LiteratureReference:8865895] Dynamic protein-protein interaction wiring of the human spliceosome [LiteratureReference:8865896] Mammalian splicing factor SF1 interacts with SURP domains of U2 snRNP-associated proteins [LiteratureReference:9770231] Association of U2 snRNP with the spliceosomal complex E [LiteratureReference:9770219] Functional association of U2 snRNP with the ATP-independent spliceosomal complex E [LiteratureReference:9771902] A compensatory base change in U1 snRNA suppresses a 5' splice site mutation [LiteratureReference:9771897] Crystal structure of human U1 snRNP, a small nuclear ribonucleoprotein particle, reveals the mechanism of 5' splice site recognition [LiteratureReference:9771907] Noncanonical registers and base pairs in human 5' splice-site selection [LiteratureReference:9773571] A cooperative interaction between U2AF65 and mBBP/SF1 facilitates branchpoint region recognition [LiteratureReference:9818109] Structure of a transcribing RNA polymerase II-U1 snRNP complex
name	Formation of the Spliceosomal E complex containing Alternative Splicing Factor
output	[Complex:9908303] Alternative Splicing Factor:pre-mRNA:Spliceosomal E complex [nucleoplasm] [Homo sapiens]
precedingEvent	[Reaction:9700862] NOVA1 binds intron of pre-mRNA [Homo sapiens]
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9908339] R-HSA-9908308.1
(hasEvent)	[Pathway:9939002] Alternative splicing of pre-RNA with Alternative Splicing Factor bound to intron [Homo sapiens]
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