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Details on Person Components of the proteasome 19S regulatory particle (19S RP...
| Class:Id | Summation:9908005 |
|---|---|
| _displayName | Components of the proteasome 19S regulatory particle (19S RP... |
| _timestamp | 2024-04-26 23:20:38 |
| created | [InstanceEdit:9908006] Orlic-Milacic, Marija, 2024-04-18 |
| literatureReference | [LiteratureReference:9907904] Molecular architecture and assembly of the eukaryotic proteasome [LiteratureReference:9908541] In-depth Analysis of the Lid Subunits Assembly Mechanism in Mammals |
| modified | [InstanceEdit:9908543] Orlic-Milacic, Marija, 2024-04-22 [InstanceEdit:9908897] Orlic-Milacic, Marija, 2024-04-23 [InstanceEdit:9909124] Orlic-Milacic, Marija, 2024-04-26 |
| text | Components of the proteasome 19S regulatory particle (19S RP) lid, PSMD3 (ortholog of yeast Rpn3), PSMD6 (ortholog of yeast Rpn7) and SEM1 (ortholog of yeast Sem1, also known as Rpn15) bind to form the complex known as the Lid particle 3 (LP3) (reviewed in Tomko and Hochstrasser 2013). The existence of the lid subcomplex composed of PSMD3 (Rpn3), PSMD6 (Rpn7), and SEM1 (Rpn15) was confirmed in human embryonic kidney cell line HEK293T (Bai et al. 2019). SEM1 interacts directly with PSMD3 and is required for binding of PSMD3 to PSMD6 (Bai et al. 2019). |
| (summation) | [Reaction:9908007] Formation of the complex of PSMD3, PSMD6, and SEM1 [Homo sapiens] |
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No pathways have been reviewed or authored by Components of the proteasome 19S regulatory particle (19S RP... (9908005)
