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Details on Person ATP activates the P2RX7 (P2X7, P2Z) trimer to passively tran...
| Class:Id | Summation:9907474 |
|---|---|
| _displayName | ATP activates the P2RX7 (P2X7, P2Z) trimer to passively tran... |
| _timestamp | 2024-04-25 22:28:06 |
| created | [InstanceEdit:9907471] May, Bruce, 2024-04-10 |
| literatureReference | [LiteratureReference:9907451] P2X7 receptors: channels, pores and more [LiteratureReference:9907602] The Elusive P2X7 Macropore [LiteratureReference:9905957] P2X7R-Panx1 Complex Impairs Bone Mechanosignaling under High Glucose Levels Associated with Type-1 Diabetes |
| modified | [InstanceEdit:9907611] May, Bruce, 2024-04-13 [InstanceEdit:9907621] May, Bruce, 2024-04-14 [InstanceEdit:9907897] May, Bruce, 2024-04-17 [InstanceEdit:9909064] May, Bruce, 2024-04-25 |
| text | ATP activates the P2RX7 (P2X7, P2Z) trimer to passively transport cations, notably calcium (Wiley et al. 1993, Humphreys et al. 1998, Wiley et al. 1998, Riedel et al. 2007, and inferred from the rat homologue, reviewed in Volonté et al. 2012, Di Virgilio et al. 2018). Calcium and sodium ions follow their concentration gradients from the extracellular region to the cytosol. In mouse osteocytes, P2rx7 is located at the plasma membrane in a complex with the Pannexin1 (Panx1) anion channel (Seref-Ferlengez et al. 2016). |
| (summation) | [Reaction:9905964] P2RX7 in ATP:P2RX7:PANX1 transports cations from the extracellular region to the cytosol [Homo sapiens] |
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No pathways have been reviewed or authored by ATP activates the P2RX7 (P2X7, P2Z) trimer to passively tran... (9907474)
