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Details on Person Pex11a gene expression is stimulated by Pparg:Rxra and Mll4,(Mll3) complex

Class:Id	BlackBoxEvent:9907261
_displayName	Pex11a gene expression is stimulated by Pparg:Rxra and Mll4,(Mll3) complex
_doRelease	TRUE
_timestamp	2025-11-04 04:30:21
authored	[InstanceEdit:9907271] Orlic-Milacic, Marija, 2024-04-05
compartment	[Compartment:7660] nucleoplasm [Compartment:17947] peroxisomal membrane
created	[InstanceEdit:9907260] Orlic-Milacic, Marija, 2024-04-05
edited	[InstanceEdit:9917569] Orlic-Milacic, Marija, 2024-08-07
input	[EntityWithAccessionedSequence:9866347] Pex11a gene [nucleoplasm] [Mus musculus]
internalReviewed	[InstanceEdit:9918118] May, Bruce, 2024-08-14 [InstanceEdit:9927587] May, Bruce, 2024-03-08 [InstanceEdit:9928383] Matthews, Lisa, 2024-11-15
isChimeric	FALSE
literatureReference	[LiteratureReference:9858073] H3.3K4M destabilizes enhancer H3K4 methyltransferases MLL3/MLL4 and impairs adipose tissue development [LiteratureReference:400203] Tissue-selective, bidirectional regulation of PEX11 alpha and perilipin genes through a common peroxisome proliferator response element [LiteratureReference:9859800] Peroxisome proliferator-activated receptor subtypes differentially cooperate with other transcription factors in selective transactivation of the perilipin/PEX11 alpha gene pair
modified	[InstanceEdit:9907517] Orlic-Milacic, Marija, 2024-04-11 [InstanceEdit:9907535] Orlic-Milacic, Marija, 2024-04-12 [InstanceEdit:9917569] Orlic-Milacic, Marija, 2024-08-07 [InstanceEdit:9917571] Orlic-Milacic, Marija, 2024-08-07 [InstanceEdit:9918005] Orlic-Milacic, Marija, 2024-08-14 [InstanceEdit:9918105] Orlic-Milacic, Marija, 2024-08-14 [InstanceEdit:9918119] Orlic-Milacic, Marija, 2024-08-14 [InstanceEdit:9919218] Orlic-Milacic, Marija, 2024-08-19 [InstanceEdit:9927588] Matthews, Lisa, 2024-11-08 [InstanceEdit:9928382] Matthews, Lisa, 2024-11-15 [InstanceEdit:9971043] Orlic-Milacic, Marija, 2025-11-04
name	Pex11a gene expression is stimulated by Pparg:Rxra and Mll4,(Mll3) complex
output	[EntityWithAccessionedSequence:9917973] Pex11a [peroxisomal membrane] [Mus musculus]
previousReviewStatus	[ReviewStatus:9821383] three stars
regulatedBy	[PositiveGeneExpressionRegulation:9918048] Positive gene expression regulation by 'Activated Pparg:Rxra:Pex11a gene:H3K4me1-Nucleosomes:Mll4,(Mll3)-ASCOM [nucleoplasm]'
releaseDate	2024-09-11
reviewed	[InstanceEdit:9970975] Aberin, Marvin Angelo E, 2025-10-31 [InstanceEdit:9970978] Wang, Shu-Ping, 2025-10-31
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48892] Mus musculus
stableIdentifier	[StableIdentifier:9907263] R-MMU-9907261.3
structureModified	[InstanceEdit:9918005] Orlic-Milacic, Marija, 2024-08-14 [InstanceEdit:9918105] Orlic-Milacic, Marija, 2024-08-14
summation	[Summation:9907262] Mouse Pex11a gene in clustered together with the Plin1 gene ...
(inferredFrom)	[BlackBoxEvent:9859005] PEX11A gene expression is stimulated by PPARG:RXRA:MLL4,(MLL3)-ASCOM complex [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9971908] Update Tracker - [BlackBoxEvent:9907261] Pex11a gene expression is stimulated by Pparg:Rxra and Mll4,(Mll3) complex - v95:[modifyText]
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