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Query author contributions in Reactome

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Details on Person Rothfels, Karen, 2024-04-04

Class:IdInstanceEdit:9907140
_displayNameRothfels, Karen, 2024-04-04
_timestamp2024-04-04 16:28:13
author[Person:1226097] Rothfels, Karen
dateTime2024-04-04 16:28:12
(created)[RegulationReference:9907133] Negative regulation by 'CREBBP [nucleoplasm]' Deacetylation by SIRT1 promotes the tumor-suppressive activity of HINT1 by enhancing its binding capacity for β-catenin or MITF in colon cancer and melanoma cells
[RegulationReference:9907134] Negative gene expression regulation by 'EDN1, EDN3:EDNRB [plasma membrane]' Endothelin B receptor blockade inhibits dynamics of cell interactions and communications in melanoma cell progression
[RegulationReference:9907135] Positive gene expression regulation by 'MITF_M dimer:TFAP2A:IRF4 gene [nucleoplasm]' A polymorphism in IRF4 affects human pigmentation through a tyrosinase-dependent MITF/TFAP2A pathway
[RegulationReference:9907136] Positive gene expression regulation by 'IRF4:TYR gene [nucleoplasm]' A polymorphism in IRF4 affects human pigmentation through a tyrosinase-dependent MITF/TFAP2A pathway
[RegulationReference:9907137] Negative gene expression regulation by 'SNAI2:CDH1 gene [nucleoplasm]' SYT-SSX1 and SYT-SSX2 interfere with repression of E-cadherin by snail and slug: a potential mechanism for aberrant mesenchymal to epithelial transition in human synovial sarcoma
[RegulationReference:9907138] Positive gene expression regulation by 'MITF-M dimer:BAF complex:TYRP1 gene [nucleoplasm]' The microphthalmia-associated transcription factor requires SWI/SNF enzymes to activate melanocyte-specific genes
[RegulationReference:9907139] Positive regulation by 'SIRT1 [nucleoplasm]' Deacetylation by SIRT1 promotes the tumor-suppressive activity of HINT1 by enhancing its binding capacity for β-catenin or MITF in colon cancer and melanoma cells
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No pathways have been reviewed or authored by Rothfels, Karen, 2024-04-04 (9907140)
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