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Details on Person CaV3.2 (Cacna1h:Cacna2d1:Cacnb1,2,3:Cacng7) transports calcium from the extracellular region to the cytosol

Class:Id	Reaction:9905968
_displayName	CaV3.2 (Cacna1h:Cacna2d1:Cacnb1,2,3:Cacng7) transports calcium from the extracellular region to the cytosol
_doRelease	TRUE
_timestamp	2024-11-05 13:26:16
authored	[InstanceEdit:9892589] May, Bruce, 2024-03-28
catalystActivity	[CatalystActivity:9905943] voltage-gated calcium channel activity of CaV3.2:heparan sulfate-Hspg2 [plasma membrane]
compartment	[Compartment:984] extracellular region [Compartment:876] plasma membrane [Compartment:70101] cytosol
created	[InstanceEdit:9905924] May, Bruce, 2024-03-29
edited	[InstanceEdit:9892589] May, Bruce, 2024-03-28
input	[SimpleEntity:74112] Ca2+ [extracellular region]
internalReviewed	[InstanceEdit:9909074] Matthews, Lisa, 2024-04-26
isChimeric	FALSE
literatureReference	[LiteratureReference:9905960] Association of the α(2)δ(1) subunit with Ca(v)3.2 enhances membrane expression and regulates mechanically induced ATP release in MLO-Y4 osteocytes [LiteratureReference:9924019] Gabapentin Disrupts Binding of Perlecan to the α₂δ₁ Voltage Sensitive Calcium Channel Subunit and Impairs Skeletal Mechanosensation
modified	[InstanceEdit:9906877] May, Bruce, 2024-04-02 [InstanceEdit:9924062] May, Bruce, 2024-10-06 [InstanceEdit:9925860] May, Bruce, 2024-10-27 [InstanceEdit:9927250] May, Bruce, 2024-11-05
name	CaV3.2 (Cacna1h:Cacna2d1:Cacnb1,2,3:Cacng7) transports calcium from the extracellular region to the cytosol
output	[SimpleEntity:74016] Ca2+ [cytosol]
releaseDate	2024-12-04
reviewed	[InstanceEdit:9925857] Farach-Carson, Mary C, 2024-10-27 [InstanceEdit:9925859] Wu, Danielle, 2024-10-27
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48892] Mus musculus
stableIdentifier	[StableIdentifier:9905991] R-MMU-9905968.1
summation	[Summation:9906866] Cacna2d1, the regulatory subunit of voltage-gated calcium ch...
(inferredFrom)	[Reaction:9905934] CaV3.2 (CACNA1H:CACNA2D1:CACNB1,2,3:CACNG7) transports calcium from the extracellular region to the cytosol [Homo sapiens]
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