Reactome: A Curated Pathway Database
THIS SITE IS USED FOR CURATION AND TESTING
IT IS NOT STABLE, IS LINKED TO AN INCOMPLETE DATA SET, AND IS NOT MONITORED FOR PERFORMANCE. WE STRONGLY RECOMMEND THE USE OF OUR PUBLIC SITE

Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Name Email address

Details on Person P2X7R-Panx1 Complex Impairs Bone Mechanosignaling under High Glucose Levels Associated with Type-1 Diabetes

Class:IdLiteratureReference:9905957
_displayNameP2X7R-Panx1 Complex Impairs Bone Mechanosignaling under High Glucose Levels Associated with Type-1 Diabetes
_timestamp2024-03-29 00:46:36
author[Person:9905920] Seref-Ferlengez, Zeynep
[Person:9905922] Maung, Stephanie
[Person:9905958] Schaffler, Mitchell B
[Person:9857633] Spray, David C
[Person:9857706] Suadicani, Sylvia O
[Person:9857658] Thi, Mia M
created[InstanceEdit:9905924] May, Bruce, 2024-03-29
journalPLoS One
pagese0155107
pubMedIdentifier27159053
titleP2X7R-Panx1 Complex Impairs Bone Mechanosignaling under High Glucose Levels Associated with Type-1 Diabetes
volume11
year2016
(literatureReference)[Summation:9907466] The P2RX7 (P2X7, P2Z) trimer binds ATP, which gates its cati...
[Summation:9907474] ATP activates the P2RX7 (P2X7, P2Z) trimer to passively tran...
[Reaction:9907464] ATP binds P2rx7 in P2rx7 trimer:Panx1 heptamer [Mus musculus]
[Complex:877242] ATP:P2X7 oligomer:PANX1 heptamer [plasma membrane] [Homo sapiens]
[Complex:9905973] P2RX7 trimer:PANX1 heptamer [plasma membrane] [Homo sapiens]
[Complex:9907468] P2rx7 trimer:Panx1 heptamer [plasma membrane] [Mus musculus]
[Complex:9907470] ATP:P2rx7 trimer:Panx1 heptamer [plasma membrane] [Mus musculus]
[Change default viewing format]
No pathways have been reviewed or authored by P2X7R-Panx1 Complex Impairs Bone Mechanosignaling under High Glucose Levels Associated with Type-1 Diabetes (9905957)