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Details on Person apo-UQCRFS1 binds LYRM7
Class:Id Reaction:9866253
_displayName apo-UQCRFS1 binds LYRM7
_doRelease TRUE
_timestamp 2024-05-21 07:57:14
authored [InstanceEdit:9866258] Stephan, Ralf, 2024-03-26
catalystActivity [CatalystActivity:9906879] protein folding chaperone activity of LYRM7 [mitochondrial matrix]
compartment [Compartment:5460] mitochondrial matrix
created [InstanceEdit:9866255] Stephan, Ralf, 2024-03-26
edited [InstanceEdit:9910822] Stephan, Ralf, 2024-05-21
input [EntityWithAccessionedSequence:9866252] LYRM7 [mitochondrial matrix] [Homo sapiens] [EntityWithAccessionedSequence:9906006] UQCRFS1(1-274) [mitochondrial matrix] [Homo sapiens]
internalReviewed [InstanceEdit:9907743] D'Eustachio, Peter, 2024-04-16
isChimeric FALSE
literatureReference [LiteratureReference:9866249] LYRM7/MZM1L is a UQCRFS1 chaperone involved in the last steps of mitochondrial Complex III assembly in human cells [LiteratureReference:9866265] Mitochondrial complex III Rieske Fe-S protein processing and assembly [LiteratureReference:9866245] LYRM7-associated mitochondrial complex III deficiency with non-cavitating leukoencephalopathy and stroke-like episodes [LiteratureReference:9854980] A Single Adaptable Cochaperone-Scaffold Complex Delivers Nascent Iron-Sulfur Clusters to Mammalian Respiratory Chain Complexes I-III
modified [InstanceEdit:9906004] Stephan, Ralf, 2024-03-29 [InstanceEdit:9906880] Stephan, Ralf, 2024-04-03 [InstanceEdit:9907742] Stephan, Ralf, 2024-04-16 [InstanceEdit:9908912] Stephan, Ralf, 2024-04-24 [InstanceEdit:9910655] Stephan, Ralf, 2024-05-16 [InstanceEdit:9910683] Stephan, Ralf, 2024-05-16 [InstanceEdit:9910689] Stephan, Ralf, 2024-05-16 [InstanceEdit:9910823] Stephan, Ralf, 2024-05-21
name apo-UQCRFS1 binds LYRM7
output [Complex:9866263] UQCRFS1(1-274):LYRM7 [mitochondrial matrix] [Homo sapiens]
precedingEvent
previousReviewStatus [ReviewStatus:9821383] three stars
releaseDate 2024-06-15
reviewed [InstanceEdit:9910688] Hill, David P, 2024-05-16
reviewStatus [ReviewStatus:9821382] five stars
species [Species:48887] Homo sapiens
stableIdentifier [StableIdentifier:9866269] R-HSA-9866253.1
structureModified [InstanceEdit:9906004] Stephan, Ralf, 2024-03-29 [InstanceEdit:9906880] Stephan, Ralf, 2024-04-03
summation [Summation:9866246] After its synthesis in the cytosol and via to the mitochondr...
(hasEvent) [Pathway:9865881] Complex III assembly [Homo sapiens]
(precedingEvent) [Reaction:9866272] 2Fe-2S is inserted in UQCRFS1 [Homo sapiens]
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No pathways have been reviewed or authored by apo-UQCRFS1 binds LYRM7 (9866253)