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Details on Person The CALCRL:RAMP2 receptor bound to ADM binds the Gs alpha su...
| Class:Id | Summation:9861334 |
|---|---|
| _displayName | The CALCRL:RAMP2 receptor bound to ADM binds the Gs alpha su... |
| _timestamp | 2024-04-03 00:31:35 |
| created | [InstanceEdit:9861304] May, Bruce, 2024-02-16 |
| literatureReference | [LiteratureReference:9861338] Molecular Mechanisms of Class B GPCR Activation: Insights from Adrenomedullin Receptors |
| modified | [InstanceEdit:9863689] May, Bruce, 2024-03-04 [InstanceEdit:9863929] May, Bruce, 2024-03-05 [InstanceEdit:9906878] May, Bruce, 2024-04-03 |
| text | The CALCRL:RAMP2 receptor bound to ADM binds the Gs alpha subunit of the heterotrimeric G protein complex G alpha s:G beta:G gamma (Weston et al. 2016, Woolley et al. 2017, Inoue et al. 2019, Liang et al. 2020, RoehrKasse et al. 2020). Activation of the CALCLR:RAMP2 receptor (AM1 receptor) results in synthesis of cAMP and activation of CREB and ERK (Garelja et al. 2020). |
| (summation) | [Reaction:9861300] ADM:CALCRL:RAMP2 binds G(s):GDP:Gbeta:Ggamma heterotrimer [Homo sapiens] |
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No pathways have been reviewed or authored by The CALCRL:RAMP2 receptor bound to ADM binds the Gs alpha su... (9861334)
