Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Details on Person ADM:CALCRL:RAMP2:G-alpha(s):GDP:G-beta:G-gamma exchanges GDP for GTP

Class:Id	Reaction:9861324
_displayName	ADM:CALCRL:RAMP2:G-alpha(s):GDP:G-beta:G-gamma exchanges GDP for GTP
_doRelease	TRUE
_timestamp	2024-07-16 10:03:05
authored	[InstanceEdit:9860942] May, Bruce, 2024-02-12
compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane
created	[InstanceEdit:9861304] May, Bruce, 2024-02-16
edited	[InstanceEdit:9860942] May, Bruce, 2024-02-12
input	[Complex:9861307] ADM:CALCLR:RAMP2:G-alpha(s):GDP:G-beta:G-gamma [plasma membrane] [Homo sapiens] [SimpleEntity:29438] GTP [cytosol]
isChimeric	FALSE
literatureReference	[LiteratureReference:432210] S111N mutation in the helical domain of human Gs(alpha) reduces its GDP/GTP exchange rate [LiteratureReference:9863685] Structural and Functional Implication of Natural Variants of Gαs [LiteratureReference:432202] Mutagenesis in the switch IV of the helical domain of the human Gsalpha reduces its GDP/GTP exchange rate [LiteratureReference:9863920] Receptor Activity-modifying Protein-directed G Protein Signaling Specificity for the Calcitonin Gene-related Peptide Family of Receptors [LiteratureReference:9863670] Receptor activity-modifying protein dependent and independent activation mechanisms in the coupling of calcitonin gene-related peptide and adrenomedullin receptors to Gs
modified	[InstanceEdit:9863689] May, Bruce, 2024-03-04 [InstanceEdit:9863929] May, Bruce, 2024-03-05 [InstanceEdit:9915797] May, Bruce, 2024-07-16
name	ADM:CALCRL:RAMP2:G-alpha(s):GDP:G-beta:G-gamma exchanges GDP for GTP
output	[SimpleEntity:29420] GDP [cytosol] [Complex:9861303] ADM:CALCRL:RAMP2:G-alpha(s):GTP:G-beta:G-gamma [plasma membrane] [Homo sapiens]
precedingEvent	[Reaction:9861300] ADM:CALCRL:RAMP2 binds G(s):GDP:Gbeta:Ggamma heterotrimer [Homo sapiens] [Reaction:9861332] ADM (Adrenomedullin) binds CALCRL:RAMP2 [Homo sapiens]
releaseDate	2024-09-11
reviewed	[InstanceEdit:9915793] Xiao, Rui, 2024-07-16
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9861348] R-HSA-9861324.1
summation	[Summation:9863641] The G-alpha(s) subunit in a complex with G-beta:G-gamma and ...
(hasEvent)	[Pathway:9856530] High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells [Homo sapiens]
(precedingEvent)	[Reaction:9861293] ADM:CALCRL:RAMP2:G-alpha(s):GTP:G-beta:G-gamma dissociates [Homo sapiens]
[Change default viewing format]

No pathways have been reviewed or authored by ADM:CALCRL:RAMP2:G-alpha(s):GDP:G-beta:G-gamma exchanges GDP for GTP (9861324)