Reactome: A Curated Pathway Database
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Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

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Details on Person TASL recruits IRF5

Class:IdReaction:9860290
_displayNameTASL recruits IRF5
_doReleaseTRUE
_timestamp2024-05-15 16:31:31
authored[InstanceEdit:9860434] Shamovsky, Veronica, 2024-02-06
compartment[Compartment:70101] cytosol
[Compartment:1660541] endolysosome membrane
created[InstanceEdit:9860252] Shamovsky, Veronica, 2024-02-01
edited[InstanceEdit:9910548] Shamovsky, Veronica, 2024-05-15
input[Complex:9860291] SLC15A4:p-S294-TASL [endolysosome membrane] [Homo sapiens]
[EntityWithAccessionedSequence:1015676] IRF5 [cytosol] [Homo sapiens]
internalReviewed[InstanceEdit:9863340] Matthews, Lisa, 2024-02-29
isChimericFALSE
literatureReference[LiteratureReference:9860259] TASL is the SLC15A4-associated adaptor for IRF5 activation by TLR7-9
modified[InstanceEdit:9860434] Shamovsky, Veronica, 2024-02-06
[InstanceEdit:9863342] Shamovsky, Veronica, 2024-02-29
[InstanceEdit:9909271] Shamovsky, Veronica, 2024-05-02
[InstanceEdit:9909428] Shamovsky, Veronica, 2024-05-13
[InstanceEdit:9910553] Shamovsky, Veronica, 2024-05-15
[InstanceEdit:9910569] Shamovsky, Veronica, 2024-05-15
nameTASL recruits IRF5
output[Complex:9860255] SLC15A4:p-S-TASL:IRF5 [endolysosome membrane] [Homo sapiens]
precedingEvent
releaseDate2024-06-15
reviewed[InstanceEdit:9909272] Löw, Christian, 2024-05-02
[InstanceEdit:9909426] Heinz, Leonhard X, 2024-05-13
[InstanceEdit:9910549] Toyama-Sorimachi, Noriko, 2024-11-15
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9860313] R-HSA-9860290.1
summation[Summation:9860410] Following activation of endosomal Toll like receptors (TLR7,...
(hasEvent)[Pathway:9860276] SLC15A4:TASL-dependent IRF5 activation [Homo sapiens]
(precedingEvent)[Reaction:9860292] Activated IKBKB phosphorylates IRF5 [Homo sapiens]
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No pathways have been reviewed or authored by TASL recruits IRF5 (9860290)