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Details on Person Retinoic acid enhances the expression of TGFBR3 (betaglycan)...

Class:IdSummation:9860117
_displayNameRetinoic acid enhances the expression of TGFBR3 (betaglycan)...
_timestamp2024-02-22 14:13:22
created[InstanceEdit:9860104] Tiwari, Krishna, 2024-01-31
literatureReference[LiteratureReference:9860148] Induction of transforming growth factor beta 1 and its receptors during all-trans-retinoic acid (RA) treatment of RA-responsive human neuroblastoma cell lines
[LiteratureReference:9840068] Betaglycan expression is transcriptionally up-regulated during skeletal muscle differentiation. Cloning of murine betaglycan gene promoter and its modulation by MyoD, retinoic acid, and transforming growth factor-beta
modified[InstanceEdit:9860192] Tiwari, Krishna, 2024-01-31
[InstanceEdit:9861994] Tiwari, Krishna, 2024-02-22
textRetinoic acid enhances the expression of TGFBR3 (betaglycan) by regulating its transcription. TGFBR3 promoter has binding sites for RA receptor and same has been confirmed through luciferase assay conducted on C2C12 cells, a differentiating myoblast cellline (Lopez-Casillas et al, 2003). TGFBR3 expression is also found to increase in a dose dependent way in human nueroblastoma cells in response to retinoic acid (Cohen et ai, 1995).
(summation)[Reaction:9860125] Binding of ATRA to TGFBR3 gene promoter [Homo sapiens]
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