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Details on Person NOCT dephosphorylates NADP+ in the mitochondrial matrix

Class:IdReaction:9859959
_displayNameNOCT dephosphorylates NADP+ in the mitochondrial matrix
_timestamp2026-03-23 17:42:51
authored[InstanceEdit:9859681] May, Bruce, 2024-01-24
catalystActivity[CatalystActivity:9859955] NADP phosphatase activity of NOCT [mitochondrial matrix]
compartment[Compartment:5460] mitochondrial matrix
created[InstanceEdit:9859836] May, Bruce, 2024-01-29
crossReference[DatabaseIdentifier:9983814] RHEA:28050
edited[InstanceEdit:9859681] May, Bruce, 2024-01-24
inferredFrom
input[SimpleEntity:113563] NADP+ [mitochondrial matrix]
[SimpleEntity:113521] H2O [mitochondrial matrix]
internalReviewed[InstanceEdit:9985656] Gillespie, Marc E, 2026-03-23
isChimericFALSE
literatureReference[LiteratureReference:9859905] Differential processing and localization of human Nocturnin controls metabolism of mRNA and nicotinamide adenine dinucleotide cofactors
[LiteratureReference:9859949] The metabolites NADP+ and NADPH are the targets of the circadian protein Nocturnin (Curled)
[LiteratureReference:9983718] Characterization of the enzymatic activity of the rhythmic human NADP(H) phosphatase, Nocturnin
modified[InstanceEdit:9982835] May, Bruce, 2026-02-19
[InstanceEdit:9983726] May, Bruce, 2026-02-26
[InstanceEdit:9983816] May, Bruce, 2026-02-27
[InstanceEdit:9985658] May, Bruce, 2026-03-23
nameNOCT dephosphorylates NADP+ in the mitochondrial matrix
output[SimpleEntity:113526] NAD+ [mitochondrial matrix]
[SimpleEntity:113548] Pi [mitochondrial matrix]
reviewStatus[ReviewStatus:9821383] three stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9859984] R-HSA-9859959.1
summation[Summation:9859916] Nocturnin (NOCT) dephosphorylates nicotinamide adenine dinuc...
(hasEvent)[Pathway:9958957] NAD+ and Sirtuins regulate the circadian clock [Homo sapiens]
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