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Details on Person MITF-M-dependent ATP6V1B2 gene expression

Class:Id	BlackBoxEvent:9858918
_displayName	MITF-M-dependent ATP6V1B2 gene expression
_doRelease	TRUE
_timestamp	2024-11-08 15:56:51
authored	[InstanceEdit:9856650] Rothfels, Karen, 2023-12-21
compartment	[Compartment:70101] cytosol [Compartment:7660] nucleoplasm
created	[InstanceEdit:9858937] Rothfels, Karen, 2024-01-14
edited	[InstanceEdit:9856650] Rothfels, Karen, 2023-12-21
input	[EntityWithAccessionedSequence:9858776] ATP6V1B2 gene [nucleoplasm] [Homo sapiens]
internalReviewed	[InstanceEdit:9859271] Orlic-Milacic, Marija, 2024-01-17
isChimeric	FALSE
literatureReference	[LiteratureReference:9857261] Mitf is a master regulator of the v-ATPase, forming a control module for cellular homeostasis with v-ATPase and TORC1 [LiteratureReference:9858868] Novel roles for the MiTF/TFE family of transcription factors in organelle biogenesis, nutrient sensing, and energy homeostasis [LiteratureReference:9858862] Rag GTPases mediate amino acid-dependent recruitment of TFEB and MITF to lysosomes [LiteratureReference:9824935] MITF drives endolysosomal biogenesis and potentiates Wnt signaling in melanoma cells [LiteratureReference:9857242] MITF has a central role in regulating starvation-induced autophagy in melanoma [LiteratureReference:9857267] The MITF family of transcription factors: Role in endolysosomal biogenesis, Wnt signaling, and oncogenesis [LiteratureReference:9730403] MITF-the first 25 years
modified	[InstanceEdit:9859473] Rothfels, Karen, 2024-01-19 [InstanceEdit:9863248] Rothfels, Karen, 2024-02-28 [InstanceEdit:9910861] Rothfels, Karen, 2024-05-21 [InstanceEdit:9927681] Rothfels, Karen, 2024-11-08
name	MITF-M-dependent ATP6V1B2 gene expression
output	[EntityWithAccessionedSequence:912598] ATP6V1B2 [cytosol] [Homo sapiens]
precedingEvent	[Reaction:9858883] MITF-M binds the promoters of v-ATPase target genes [Homo sapiens] [Reaction:9857375] MITF dimerizes [Homo sapiens]
previousReviewStatus	[ReviewStatus:9821383] three stars
regulatedBy	[PositiveGeneExpressionRegulation:9858914] Positive gene expression regulation by 'MITF-M dimer:ATP6V1B2 gene [nucleoplasm]'
regulationReference	[RegulationReference:9858936] Positive gene expression regulation by 'MITF-M dimer:ATP6V1B2 gene [nucleoplasm]' Mitf is a master regulator of the v-ATPase, forming a control module for cellular homeostasis with v-ATPase and TORC1
releaseDate	2024-03-27
reviewed	[InstanceEdit:9863245] Arnheiter, Heinz, 2024-02-26 [InstanceEdit:9910860] de la Serna, Ivana L, 2024-05-21 [InstanceEdit:9927254] Vu, Hong Nhung, 2024-11-05 [InstanceEdit:9927252] Steingr�msson, Eir�kur, 2024-11-05
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9858943] R-HSA-9858918.3
summation	[Summation:9859439] MITF has been implicated in the regulation of expression of ...
(hasEvent)	[Pathway:9857377] Regulation of MITF-M-dependent genes involved in lysosome biogenesis and autophagy [Homo sapiens]
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No pathways have been reviewed or authored by MITF-M-dependent ATP6V1B2 gene expression (9858918)